Search results
- 1.0535103 - BTÚ 2021 RIV GB eng J - Journal Article
Hubáčková, Soňa - Davidová, Eliška - Boukalová, Štěpána - Kovářová, Jaromíra - Bajziková, Martina - Coelho, Ana R. - Terp, M. G. - Ditzel, H. J. - Rohlena, Jakub - Neužil, Jiří
Replication and ribosomal stress induced by targeting pyrimidine synthesis and cellular checkpoints suppress p53-deficient tumors.
Cell Death & Disease. Roč. 11, č. 2 (2020), č. článku 110. ISSN 2041-4889. E-ISSN 2041-4889
R&D Projects: GA ČR(CZ) GA17-07635S; GA ČR(CZ) GA18-02550S; GA ČR(CZ) GC17-01192J; GA ČR GA17-20904S; GA ČR(CZ) GA20-18513S; GA ČR GA19-20553S; GA MZd(CZ) NV17-30138A
Institutional support: RVO:86652036
Keywords : de-novo synthesis * dihydroorotate dehydrogenase * dna-replication * protein l11 * inhibition
OECD category: Cell biology
Impact factor: 8.469, year: 2020
Method of publishing: Open access
https://www.nature.com/articles/s41419-020-2224-7.pdf
Permanent Link: http://hdl.handle.net/11104/0313253 - 2.0520732 - BTÚ 2020 RIV DE eng J - Journal Article
Hubáčková, Soňa - Novais, Silvia Magalhaes - Davidová, Eliška - Neužil, Jiří - Rohlena, Jakub
Mitochondria-driven elimination of cancer and senescent cells.
Biological Chemistry. Roč. 400, č. 2 (2019), s. 141-148. ISSN 1431-6730. E-ISSN 1437-4315
R&D Projects: GA ČR GA17-20904S; GA ČR GA16-22823S; GA ČR(CZ) GA18-02550S; GA ČR(CZ) GC17-01192J; GA ČR GA16-12719S; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:86652036
Keywords : cellular senescence * oxidative stress * contributes * suppression * respiration
OECD category: Biochemistry and molecular biology
Impact factor: 3.270, year: 2019
Method of publishing: Open access
https://www.nature.com/articles/s41418-018-0118-3
Permanent Link: http://hdl.handle.net/11104/0305579 - 3.0520704 - BTÚ 2020 RIV US eng J - Journal Article
Hubáčková, Soňa - Davidová, Eliška - Rohlenová, Kateřina - Štursa, Jan - Werner, Lukáš - Anděra, Ladislav - Dong, L. - Terp, M. G. - Hodný, Zdeněk - Ditzel, H. J. - Rohlena, Jakub - Neužil, Jiří
Selective elimination of senescent cells by mitochondrial targeting is regulated by ANT2.
Cell Death and Differentiation. Roč. 26, č. 2 (2019), s. 276-290. ISSN 1350-9047. E-ISSN 1476-5403
R&D Projects: GA ČR(CZ) GA18-02550S; GA ČR(CZ) GA17-07635S; GA ČR GA15-02203S; GA ČR GA16-22823S; GA ČR GA17-20904S; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT(CZ) LM2015062
Institutional support: RVO:86652036 ; RVO:68378050
Keywords : oncogene-induced senescence * cellular senescence * oxidative stress * dna-damage
OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (UMG-J)
Impact factor: 10.717, year: 2019
Method of publishing: Open access
https://www.nature.com/articles/s41418-018-0118-3
Permanent Link: http://hdl.handle.net/11104/0305395 - 4.0504151 - BTÚ 2020 RIV US eng J - Journal Article
Bajziková, Martina - Kovářová, Jaromíra - Coelho, Ana R. - Boukalová, Štěpána - Oh, S. - Rohlenová, Kateřina - Švec, David - Hubáčková, Soňa - Endaya, B. - Judasová, Kateřina - Bezawork-Geleta, A. - Klučková, Katarína - Chatre, L. - Zobalová, Renata - Nováková, Anna - Váňová, Kateřina - Ezrová, Zuzana - Maghzal, G. J. - Novais, Silvia Magalhaes - Olsinova, M. - Krobová, Linda - An, Y. J. - Davidová, Eliška - Nahácka, Zuzana - Sobol, Margaryta - Cunha-Oliveira, T. - Sandoval-Acuna, Cristian - Strnad, Hynek - Zhang, T. - Huynh, T. - Serafim, T. L. - Hozák, Pavel - Sardao, V. A. - Koopman, W. J. H. - Ricchetti, M. - Oliveira, P. J. - Kolář, František - Kubista, Mikael - Truksa, Jaroslav - Dvořáková-Hortová, Kateřina - Pacak, K. - Gürlich, R. - Stocker, R. - Zhou, Y. - Berridge, M.V. - Park, S. - Dong, L. - Rohlena, Jakub - Neužil, Jiří
Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells.
Cell Metabolism. Roč. 29, č. 2 (2019), s. 399-416. ISSN 1550-4131. E-ISSN 1932-7420
R&D Projects: GA ČR GA15-02203S; GA ČR GA16-12719S; GA ČR GA17-20904S; GA ČR GA16-22823S; GA ČR(CZ) GA16-12816S; GA ČR(CZ) GA18-11275S; GA ČR(CZ) GA18-02550S; GA MZd(CZ) NV16-31604A; GA MZd(CZ) NV17-30138A; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) LM2015062; GA ČR(CZ) GJ18-24753Y; GA MŠMT(CZ) EF16_013/0001775
Institutional support: RVO:86652036 ; RVO:67985823 ; RVO:68378050
Keywords : ELECTRON-TRANSPORT CHAIN * PANCREATIC-CANCER * MITOCHONDRIA
OECD category: Cell biology; Physiology (including cytology) (FGU-C); Cell biology (UMG-J)
Impact factor: 21.567, year: 2019
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S1550413118306466?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0295861 - 5.0492386 - BTÚ 2019 RIV GB eng J - Journal Article
Bezawork-Geleta, A. - Wen, H. - Dong, L. F. - Yan, B. - Vider, J. - Boukalová, Štěpána - Krobová, Linda - Váňová, Kateřina - Zobalová, Renata - Sobol, Margaryta - Hozák, Pavel - Novais, Silvia Magalhaes - Caisova, V. - Abaffy, Pavel - Naraine, Ravindra - Pang, Y. - Zaw, T. - Zhang, P. - Šindelka, Radek - Kubista, Mikael - Zuryn, S. - Molloy, M. P. - Berridge, M.V. - Pacak, K. - Rohlena, Jakub - Park, S. - Neužil, Jiří
Alternative assembly of respiratory complex II connects energy stress to metabolic checkpoints.
Nature Communications. Roč. 9, JUN 7 2018 (2018), č. článku 2221. ISSN 2041-1723. E-ISSN 2041-1723
R&D Projects: GA ČR GA15-02203S; GA MZd NV17-30138A; GA ČR GA17-20904S; GA MŠMT(CZ) LM2015062; GA MŠMT(CZ) ED1.1.00/02.0109; GA ČR GA16-22823S
Institutional support: RVO:86652036 ; RVO:68378050
Keywords : ELECTRON-TRANSPORT CHAIN * PYRUVATE-KINASE M2 * MITOCHONDRIAL-DNA MUTATIONS
OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (UMG-J)
Impact factor: 11.878, year: 2018
Permanent Link: http://hdl.handle.net/11104/0286410 - 6.0481503 - BTÚ 2018 RIV US eng J - Journal Article
Blecha, Jan - Novais, Silvia Magalhaes - Rohlenová, Kateřina - Novotná, Eliška - Lettlová, Sandra - Schmitt, S. - Zischka, H. - Neužil, Jiří - Rohlena, Jakub
Antioxidant defense in quiescent cells determines selectivity of electron transport chain inhibition-induced cell death.
Free Radical Biology and Medicine. Roč. 112, NOV 2017 (2017), s. 253-266. ISSN 0891-5849. E-ISSN 1873-4596
R&D Projects: GA ČR GA16-22823S; GA ČR GA17-20904S; GA ČR GA16-12719S; GA MZd(CZ) NV16-31604A; GA MŠMT(CZ) LM2015062; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:86652036
Keywords : Electron transport chain * Supercomplexes * Antioxidant defense * SOD2
OECD category: Biochemistry and molecular biology
Impact factor: 6.020, year: 2017
Permanent Link: http://hdl.handle.net/11104/0277051 - 7.0474448 - BTÚ 2018 RIV GB eng J - Journal Article
Bezawork-Geleta, A. - Rohlena, Jakub - Dong, L. - Pacak, K. - Neužil, Jiří
Mitochondrial Complex II: At the Crossroads.
Trends in Biochemical Sciences. Roč. 42, č. 4 (2017), s. 312-325. ISSN 0968-0004. E-ISSN 1362-4326
R&D Projects: GA ČR GA15-02203S; GA ČR(CZ) GA16-12719S; GA ČR GA17-20904S; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:86652036
Keywords : GASTROINTESTINAL STROMAL TUMORS * SUCCINATE-DEHYDROGENASE ACTIVITY * ALPHA-TOCOPHERYL SUCCINATE
OECD category: Cell biology
Impact factor: 15.678, year: 2017
Permanent Link: http://hdl.handle.net/11104/0271499 - 8.0474268 - BTÚ 2018 RIV US eng J - Journal Article
Dong, L. F. - Kovářová, Jaromíra - Bajziková, Martina - Bezawork-Geleta, A. - Švec, David - Endaya, B. - Sachaphibulkij, K. - Coelho, Ana R. - Šebková, Nataša - Ruzickova, A. - Tan, A.S. - Klučková, Katarína - Judasová, Kateřina - Zamecnikova, K. - Rychtarčíková, Zuzana - Gopalan, V. - Anděra, Ladislav - Sobol, Margaryta - Yan, B. - Pattnaik, B. - Bhatraju, N. - Truksa, Jaroslav - Stopka, P. - Hozák, Pavel - Lam, A. K. - Sedláček, Radislav - Oliveira, P.J. - Kubista, Mikael - Agrawal, A. - Dvořáková-Hortová, Kateřina - Rohlena, Jakub - Berridge, M.V. - Neužil, Jiří
Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondria! DNA-deficient cancer cells.
eLife. Roč. 6, 15 Febr 2017 (2017), č. článku e22187. ISSN 2050-084X. E-ISSN 2050-084X
R&D Projects: GA ČR(CZ) GA16-12816S; GA MŠMT(CZ) LM2011032; GA ČR(CZ) GA16-22823S; GA ČR GA17-20904S; GA MŠMT LO1419; GA ČR(CZ) GA16-12719S; GA ČR GA15-02203S; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:86652036 ; RVO:68378050
Keywords : SUPPORTING ASPARTATE BIOSYNTHESIS * ELECTRON-TRANSPORT CHAIN * OXIDATIVE-PHOSPHORYLATION
OECD category: Biochemistry and molecular biology; Health-related biotechnology (UMG-J)
Impact factor: 7.616, year: 2017
Permanent Link: http://hdl.handle.net/11104/0271401