Search results
- 1.0584843 - ÚMG 2025 US eng J - Journal Article
Sunny, Sweetu Susan - Láchová, Jitka - Kašpárek, P. - Pálková, Marcela - Špoutil, František - Procházka, Jan - Sedláček, Radislav - Lišková, P. - Kozmik, Zbyněk
Ovol2 promoter mutations in mice and human illuminate species-specific phenotypic divergence.
Human Molecular Genetics. Roč. 33, č. 6 (2024), s. 491-500. ISSN 0964-6906. E-ISSN 1460-2083
R&D Projects: GA ČR GA21-27364S; GA MŠMT(CZ) LM2018126; GA MŠMT LM2023036; GA MŠMT EF18_046/0015861; GA MŠMT ED2.1.00/19.0395; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:68378050
Keywords : polymorphous corneal-dystrophy * epithelial-mesenchymal transition * noncoding mutations * drosophila-ovo * expression * zeb1 * gene * classification * identification * suppression * cornea * ppcd1 * Ovol2 * pathogenic variant * corneal endothelium
OECD category: Biochemistry and molecular biology
Impact factor: 3.5, year: 2022
Method of publishing: Limited access
https://academic.oup.com/hmg/article-abstract/33/6/491/7424510?redirectedFrom=fulltext&login=false
Permanent Link: https://hdl.handle.net/11104/0352866 - 2.0581626 - ÚMG 2024 RIV US eng J - Journal Article
Kubik-Zahorodna, Agnieszka - Procházka, Jan - Sedláček, Radislav
Behavioral Characterization of an Angelman Syndrome Mouse Model.
Jove-Journal of Visualized Experiments. Roč. 2023, č. 200 (2023), č. článku e65182. ISSN 1940-087X
R&D Projects: GA MŠMT(CZ) LM2018126; GA MŠMT EF16_013/0001789; GA MŠMT EF18_046/0015861; GA MŠMT ED2.1.00/19.0395; GA MŠMT LM2023036
Institutional support: RVO:68378050
Keywords : Angelman Syndrome * Animals * Behavior * Animal * Disease Models
OECD category: Biochemistry and molecular biology
Impact factor: 1.2, year: 2022
Method of publishing: Limited access
https://www.jove.com/t/65182/behavioral-characterization-of-an-angelman-syndrome-mouse-model
Permanent Link: https://hdl.handle.net/11104/0349879 - 3.0579804 - ÚMG 2024 RIV US eng J - Journal Article
Mejdrova, I. - Dušek, J. - Škach, K. - Štefela, A. - Škoda, J. - Chalupský, Karel - Dohnalová, Klára - Pávková, I. - Kronenberger, T. - Rashidian, A. - Smutná, L. - Duchoslav, V. - Smutný, T. - Pávek, P. - Nencka, R.
Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure.
Journal of Medicinal Chemistry. Roč. 66, č. 4 (2023), s. 2422-2456. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) LM2015040; GA ČR GA22-05167S; GA MŠMT ED2.1.00/19.0395
Institutional support: RVO:68378050
Keywords : pregnane-x-receptor * car * activation * pxr * ligand * derivatives * identification * artemisinin * metabolites * expression
OECD category: Cell biology
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01140
Permanent Link: https://hdl.handle.net/11104/0348603 - 4.0578356 - ÚMG 2024 RIV US eng J - Journal Article
Kemmler, C. L. - Smolíková, Jana - Moran, H. R. - Mannion, B. J. - Knapp, D. - Lim, F. - Czarkwiani, A. - Aguayo, V. H. - Rapp, V. - Fitch, O. E. - Botschi, S. - Selleri, L. - Farley, E. - Braasch, I. - Yun, M. - Visel, A. - Osterwalder, M. - Mosimann, C. - Kozmik, Zbyněk - Burger, A.
Conserved enhancers control notochord expression of vertebrate Brachyury.
Nature Communications. Roč. 14, č. 1 (2023), s. 6594. E-ISSN 2041-1723
R&D Projects: GA MŠMT(CZ) LM2018126; GA MŠMT ED2.1.00/19.0395; GA MŠMT(CZ) ED1.1.00/02.0109; GA ČR GA23-07056S
Institutional support: RVO:68378050
Keywords : transcription factors * Brachyury/T/TBXT * notochord expression
OECD category: Biochemistry and molecular biology
Impact factor: 16.6, year: 2022
Method of publishing: Open access
https://www.nature.com/articles/s41467-023-42151-3
Permanent Link: https://hdl.handle.net/11104/0347411 - 5.0574410 - ÚMG 2024 RIV DE eng J - Journal Article
Oestereicher, M. A. - Wotton, J. M. - Ayabe, S. - Bou About, G. - Cheng, T. K. - Choi, J. - Clary, D. - Dew, E. M. - Elfertak, L. - Guimond, A. - Haseli Mashhadi, H. - Heaney, J. D. - Kelsey, L. - Keskivali-Bond, P. - Lopez Gomez, F. - Marschall, S. - McFarland, M. - Meziane, H. - Munoz Fuentes, V. - Nam, K. - Nichtová, Zuzana - Pimm, D. - Bower, L. - Procházka, Jan - Rozman, Jan - Santos, L. - Stewart, M. - Tanaka, N. - Ward, Ch. S. - Willett, A. M. E. - Sedláček, Radislav … Total 51 authors
Comprehensive ECG reference intervals in C57BL/6N substrains provide a generalizable guide for cardiac electrophysiology studies in mice.
Mammalian Genome. Roč. 34, č. 2 (2023), s. 180-199. ISSN 0938-8990. E-ISSN 1432-1777
R&D Projects: GA MŠMT ED2.1.00/19.0395; GA MŠMT(CZ) LM2015040; GA MŠMT(CZ) LM2018126; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT EF16_013/0001789; GA MŠMT EF18_046/0015861
Institutional support: RVO:68378050
Keywords : Electrocardiography * Electrophysiologic Techniques * Inbred C57BL * C57BL mouse * heart function test
OECD category: Biochemistry and molecular biology
Impact factor: 2.5, year: 2022
Method of publishing: Open access
https://link.springer.com/article/10.1007/s00335-023-09995-y
Permanent Link: https://hdl.handle.net/11104/0344738 - 6.0573452 - ÚMG 2024 RIV DE eng J - Journal Article
Lindovský, Jiří - Nichtová, Zuzana - Dragano, N. R. V. - Pajuelo Reguera, David - Procházka, Jan - Fuchs, H. - Marschall, S. - Gailus-Durner, V. - Sedláček, Radislav - Hrabě de Angelis, M. - Rozman, Jan - Spielmann, N.
A review of standardized high-throughput cardiovascular phenotyping with a link to metabolism in mice.
Mammalian Genome. Roč. 34, č. 2 (2023), s. 107-122. ISSN 0938-8990. E-ISSN 1432-1777
R&D Projects: GA MŠMT(CZ) LM2018126; GA MŠMT LM2023036; GA MŠMT EF18_046/0015861; GA MŠMT EF16_013/0001789; GA MŠMT ED2.1.00/19.0395
Institutional support: RVO:68378050
Keywords : cardiovascular phenotyping * mice * metabolism * cardiovascular diseases
OECD category: Biochemistry and molecular biology
Impact factor: 2.5, year: 2022
Method of publishing: Open access
https://link.springer.com/article/10.1007/s00335-023-09997-w
Permanent Link: https://hdl.handle.net/11104/0343906 - 7.0573381 - ÚOCHB 2024 RIV GB eng J - Journal Article
Karnošová, Alena - Strnadová, Veronika - Železná, Blanka - Kuneš, Jaroslav - Kašpárek, Petr - Maletínská, Lenka
NPFFR2-deficient mice fed a high-fat diet develop strong intolerance to glucose.
Clinical science. Roč. 137, č. 10 (2023), s. 847-862. ISSN 0143-5221. E-ISSN 1470-8736
R&D Projects: GA ČR(CZ) GA21-03691S; GA MŠMT(CZ) LX22NPO5104; GA MŠMT ED2.1.00/19.0395; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT(CZ) LM2018126
Institutional support: RVO:61388963 ; RVO:68378050
Keywords : glucose intolerance * high-fat diet * insulin resistance * knockout mice * neuropeptide FF
OECD category: Physiology (including cytology); Biochemistry and molecular biology (UMG-J)
Impact factor: 6, year: 2022
Method of publishing: Open access
https://doi.org/10.1042/CS20220880
Permanent Link: https://hdl.handle.net/11104/0343845File Download Size Commentary Version Access 10.1042CS20220880.pdf 1 7.8 MB Publisher’s postprint open-access - 8.0571419 - ÚMG 2024 RIV US eng J - Journal Article
Špoutil, František - Aranaz-Novaliches, Gorreti - Procházková, Michaela - Wald, T. - Novosadová, Vendula - Kašpárek, Petr - Osička, Radim - Reseland, J. E. - Lyngstadaas, S. P. - Tiainen, H. - Boušová, Kristýna - Vondrášek, Jiří - Sedláček, Radislav - Procházka, Jan
Early evolution of enamel matrix proteins is reflected by pleiotropy of physiological functions.
Scientific Reports. Roč. 13, č. 1 (2023), č. článku 1471. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA ČR GJ19-19025Y; GA MŠMT(CZ) EF16_013/0001775; GA MŠMT EF16_013/0001789; GA MŠMT EF18_046/0015861; GA MŠMT ED2.1.00/19.0395; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) LM2018126; GA MŠMT(CZ) LM2018133; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LM2023053
Research Infrastructure: CCP II - 90126; CCP III - 90236
Institutional support: RVO:68378050 ; RVO:61388971 ; RVO:61388963
Keywords : Dental Enamel Proteins * Animals * Amelogenin * Mice
OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (MBU-M); Biochemistry and molecular biology (UOCHB-X)
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://www.nature.com/articles/s41598-023-28388-4
Permanent Link: https://hdl.handle.net/11104/0342646 - 9.0570587 - ÚMG 2024 RIV CH eng J - Journal Article
Syding, Linn Amanda - Kubik-Zahorodna, Agnieszka - Reguera, David Pajuelo - Nickl, Petr - Hrušková, Bohdana - Králíková, Michaela - Kopkanová, Jana - Novosadová, Vendula - Kašpárek, Petr - Procházka, Jan - Rozman, Jan - Tureček, Rostislav - Sedláček, Radislav
Ablation of Gabra5 Influences Corticosterone Levels and Anxiety-like Behavior in Mice.
Genes. Roč. 14, č. 2 (2023), č. článku 285. E-ISSN 2073-4425
R&D Projects: GA MŠMT(CZ) LM2018126; GA MŠMT EF16_013/0001789; GA MŠMT EF18_046/0015861; GA MŠMT ED2.1.00/19.0395; GA ČR(CZ) GA19-09283S
EU Projects: European Commission(XE) 765269 - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
Grant - others:AV ČR(CZ) StrategieAV21/29
Program: StrategieAV
Institutional support: RVO:68378041 ; RVO:68378050
Keywords : corticosterone * GABA receptor * anxiety * behavior * mouse model
OECD category: Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions (pharmacogenomics, gene-based therapeutics); Neurosciences (including psychophysiology (UEM-P)
Impact factor: 3.5, year: 2022
Method of publishing: Open access
https://www.mdpi.com/2073-4425/14/2/285
Permanent Link: https://hdl.handle.net/11104/0341891 - 10.0569557 - ÚMG 2024 RIV GB eng J - Journal Article
Tsyklauri, Oksana - Chadimová, Tereza - Niederlová, Veronika - Kovářová, Jiřina - Michálik, Juraj - Malátová, Iva - Janušová, Šárka - Ivashchenko, Olha - Rossez, H. - Drobek, Aleš - Večeřová, Hana - Galati, V. - Kovář, Marek - Štěpánek, Ondřej
Regulatory T cells suppress the formation of potent KLRK1 and IL- 7R expressing effector CD8 T cells by limiting IL-2.
eLife. Roč. 12, Jan 27 (2023), č. článku e79342. ISSN 2050-084X. E-ISSN 2050-084X
R&D Projects: GA MŠMT(CZ) LX22NPO5103; GA MŠMT LX22NPO5102; GA ČR GJ19-03435Y; GA ČR(CZ) GA22-20548S; GA ČR GA22-18046S; GA MŠMT(CZ) LM2015040; GA MŠMT(CZ) LM2018126; GA MŠMT ED2.1.00/19.0395; GA MŠMT(CZ) ED1.1.00/02.0109
EU Projects: European Commission(XE) 802878 - FunDiT
Institutional support: RVO:68378050 ; RVO:61388971
Keywords : IL-2 * T cells * autoimmunity * cytotoxic * immune suppression * immunology * inflammation * mouse * regulatory T cells
OECD category: Immunology; Immunology (MBU-M)
Impact factor: 7.7, year: 2022
Method of publishing: Open access
https://elifesciences.org/articles/79342
Permanent Link: https://hdl.handle.net/11104/0340929File Download Size Commentary Version Access elife-Tsyklauri O.-2023.pdf 0 3.4 MB Publisher’s postprint open-access