Search results

  1. 1.
    0575506 - BC 2024 RIV CH eng J - Journal Article
    Mariewskaya, K.A. - Gvozdev, D.A. - Chistov, A.A. - Straková, Petra - Huvarová, I. - Svoboda, Pavel - Kotouček, J. - Ivanov, N.M. - Krasilnikov, M.S. - Zhitlov, M.Y. - Pak, A.M. - Mikhnovets, I.E. - Nikitin, T.D. - Korshun, V.A. - Alferova, V.A. - Mašek, J. - Růžek, Daniel - Eyer, Luděk - Ustinov, A.V.
    Membrane-targeting perylenylethynylphenols inactivate medically important coronaviruses via the singlet oxygen photogeneration mechanism.
    Molecules. Roč. 28, č. 17 (2023), č. článku 6278. E-ISSN 1420-3049
    R&D Projects: GA MŠMT(CZ) LX22NPO5103
    Institutional support: RVO:60077344
    Keywords : perylene * photosensitizers * antivirals * singlet oxygen * SARS-CoV-2
    OECD category: Virology
    Impact factor: 4.6, year: 2022
    Method of publishing: Open access
    https://www.mdpi.com/1420-3049/28/17/6278
    Permanent Link: https://hdl.handle.net/11104/0345266
    FileDownloadSizeCommentaryVersionAccess
    Mariewskaya_2023_Molecules.pdf41.6 MBPublisher’s postprintopen-access
     
     
  2. 2.
    0574493 - BC 2024 RIV NL eng J - Journal Article
    Straková, Petra - Bednář, Petr - Kotouček, J. - Holoubek, Jiří - Fořtová, A. - Svoboda, Pavel - Štefánik, M. - Huvarová, I. - Šimečková, P. - Mašek, J. - Gvozdev, D.A. - Mikhnovets, I.E. - Chistov, A.A. - Nikitin, T.D. - Krasilnikov, M.S. - Ustinov, A. - Alferova, V.A. - Korshun, V.A. - Růžek, Daniel - Eyer, Luděk
    Antiviral activity of singlet oxygen-photogenerating perylene compounds against SARS-CoV-2: Interaction with the viral envelope and photodynamic virion inactivation.
    Virus Research. Roč. 334, SEPT (2023), č. článku 199158. ISSN 0168-1702. E-ISSN 1872-7492
    R&D Projects: GA MŠMT(CZ) LX22NPO5103
    Institutional support: RVO:60077344
    Keywords : SARS-CoV-2 * Perylene-related compound * Antiviral activity * Membrane * Liposome * Photodynamic inactivation
    OECD category: Virology
    Impact factor: 5, year: 2022
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S016817022300120X?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0345239
    FileDownloadSizeCommentaryVersionAccess
    Strakova_2023_VirRes.pdf111.7 MBPublisher’s postprintopen-access
     
     
  3. 3.
    0562611 - BC 2023 RIV GB eng J - Journal Article
    Duraisamy, G.S. - Jo, E. - Huvarová, I. - Park, K. H. - Heger, Z. - Adam, V. - Růžek, Daniel - Windisch, M.P. - Miller, A. D.
    Selected ginsenosides interfere efficiently with hepatitis B virus mRNA expression levels and suppress viral surface antigen secretion.
    Heliyon. Roč. 8, č. 9 (2022), č. článku e10465. ISSN 2405-8440. E-ISSN 2405-8440
    Institutional support: RVO:60077344
    Keywords : Ginsenoside * Hepatitis B virus * Lamivudine * Nucleoside/nucleotide analogues * Hepatitis B surface protein * Hepatitis B surface antigen * Chronic hepatitis B virus * Drug combinations
    OECD category: Microbiology
    Impact factor: 4, year: 2022
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S2405844022017534?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0338676
     
     
  4. 4.
    0557410 - BC 2023 RIV GB eng J - Journal Article
    Holoubek, Jiří - Bednářová, Klára - Haviernik, Jan - Huvarová, I. - Dvořáková, Zuzana - Černý, J. - Outlá, Martina - Salát, Jiří - Konkoľová, Eva - Bouřa, Evžen - Růžek, Daniel - Vorlíčková, Michaela - Eyer, Luděk - Renčiuk, Daniel
    Guanine quadruplexes in the RNA genome of the tick-borne encephalitis virus: their role as a new antiviral target and in virus biology.
    Nucleic Acids Research. Roč. 50, č. 8 (2022), s. 4574-4600. ISSN 0305-1048. E-ISSN 1362-4962
    R&D Projects: GA ČR(CZ) GA20-20229S; GA MŠMT EF15_003/0000477
    Institutional support: RVO:60077344 ; RVO:68081707 ; RVO:61388963
    Keywords : intercalator displacement assay * forming sequences * small-molecule * binding * dna * fluorescence * zika * identification * pyridostatin * inactivation
    OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (BFU-R); Biochemistry and molecular biology (UOCHB-X)
    Impact factor: 14.9, year: 2022
    Method of publishing: Open access
    https://academic.oup.com/nar/article/50/8/4574/6568495?login=true
    Permanent Link: https://hdl.handle.net/11104/0339132
     
     
  5. 5.
    0555514 - BC 2023 RIV CH eng J - Journal Article
    Štefánik, M. - Bhosale, D. - Haviernik, Jan - Straková, Petra - Fojtiková, M. - Dufková, L. - Huvarová, I. - Salát, J. - Bartáček, J. - Svoboda, J. - Sedlák, M. - Růžek, Daniel - Miller, A. - Eyer, Luděk
    Diphyllin Shows a Broad-Spectrum Antiviral Activity against Multiple Medically Important Enveloped RNA and DNA Viruses.
    Viruses. Roč. 14, č. 2 (2022), č. článku 354. E-ISSN 1999-4915
    R&D Projects: GA MŠMT(CZ) LTAUSA18016
    Institutional support: RVO:60077344
    Keywords : v-atpase inhibitor * lignans * glycosides * cells * arylnaphthalene * enveloped virus * diphyllin * cleistanthin B * vacuolar ATPase inhibitor * antiviral activity * cytotoxicity
    OECD category: Microbiology
    Impact factor: 4.7, year: 2022
    Method of publishing: Open access
    https://www.mdpi.com/1999-4915/14/2/354
    Permanent Link: https://hdl.handle.net/11104/0340396
     
     
  6. 6.
    0541187 - BC 2022 RIV US eng J - Journal Article
    Eyer, Luděk - Svoboda, P. - Balvan, J. - Vicar, T. - Raudenská, M. - Štefánik, M. - Haviernik, J. - Huvarová, I. - Straková, P. - Rudolf, Ivo - Hubálek, Zdeněk - Seley-Radtke, K. - De Clercq, E. - Růžek, Daniel
    Broad-spectrum antiviral activity of 3′-deoxy-3′-fluoroadenosine against emerging flaviviruses.
    Antimicrobial Agents and Chemotherapy. Roč. 65, č. 2 (2021), č. článku e01522-20. ISSN 0066-4804. E-ISSN 1098-6596
    R&D Projects: GA MŠMT(CZ) LTAUSA18016
    Institutional support: RVO:60077344 ; RVO:68081766
    Keywords : west nile virus * selective-inhibition * error catastrophe * in-vitro * borne * sofosbuvir * analogs * targets * future * agents * nucleoside analogue * 3'-deoxy-3'-fluoroadenosine * flavivirus * tick-borne encephalitis virus * antiviral activity * cytotoxicity * mouse model
    OECD category: Microbiology; Microbiology (UBO-W)
    Impact factor: 5.938, year: 2021
    Method of publishing: Open access
    https://aac.asm.org/content/65/2/e01522-20
    Permanent Link: http://hdl.handle.net/11104/0318790
     
     
  7. 7.
    0537313 - BC 2021 RIV CH eng J - Journal Article
    Duraisamy, G.S. - Bhosale, D. - Lipenská, I. - Huvarová, I. - Růžek, Daniel - Windisch, M.P. - Miller, A.D.
    Advanced Therapeutics, Vaccinations, and Precision Medicine in the Treatment and Management of Chronic Hepatitis B Viral Infections, Where Are We and Where Are We Going?
    Viruses. Roč. 12, č. 9 (2020), č. článku 998. E-ISSN 1999-4915
    Institutional support: RVO:60077344
    Keywords : genome-wide association * tenofovir disoproxil fumarate * zinc-finger nucleases * virus-replication * in-vivo * t-cells * rnai therapeutics * fanconi-syndrome * dp variants * genotype-e * lipid-based nanoparticles * biophysics * nanomedicine * nanotechnology * plasmid DNA * RNA interference * small interfering RNA * active pharmaceutical ingredient * precision medicine * personalized medicine * precision therapeutics approach * hepatitis B virus
    OECD category: Microbiology
    Impact factor: 5.048, year: 2020
    Method of publishing: Open access
    https://www.mdpi.com/1999-4915/12/9/998
    Permanent Link: http://hdl.handle.net/11104/0315039
     
     
  8. 8.
    0466491 - ÚOCHB 2017 RIV US eng J - Journal Article
    Eyer, L. - Nencka, Radim - Huvarová, I. - Palus, Martin - Alves, M. J. - Gould, E. A. - De Clercq, E. - Růžek, Daniel
    Nucleoside Inhibitors of Zika Virus.
    Journal of Infectious Diseases. Roč. 214, č. 5 (2016), s. 707-711. ISSN 0022-1899. E-ISSN 1537-6613
    Institutional support: RVO:61388963 ; RVO:60077344
    Keywords : Zika virus * flavivirus * nucleoside analogue * antiviral * therapy
    Subject RIV: CC - Organic Chemistry; EE - Microbiology, Virology (BC-A)
    Impact factor: 6.273, year: 2016
    Permanent Link: http://hdl.handle.net/11104/0264772
     
     


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