Search results
- 1.0586357 - ÚOCHB 2025 RIV NL eng J - Journal Article
Zamani, Mohammad Reza - Hadzima, Martin - Blažková, Kristýna - Šubr, Vladimír - Ormsby, Tereza - Celis-Gutierrez, J. - Malissen, B. - Kostka, Libor - Etrych, Tomáš - Šácha, Pavel - Konvalinka, Jan
Polymer-based antibody mimetics (iBodies) target human PD-L1 and function as a potent immune checkpoint blocker.
Journal of Biological Chemistry. Roč. 300, č. 6 (2024), č. článku 107325. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA MŠMT LX22NPO5102; GA ČR(CZ) GA23-05642S
Institutional support: RVO:61388963 ; RVO:61389013
Keywords : antibody mimetic * HPMA copolymer * mmune checkpoint * immunosuppression * immunotherapy * inhibitor * PD-1 * PD-L1 * T-cell * tumor immunology
Subject RIV: CD - Macromolecular Chemistry (UMCH-V)
OECD category: Polymer science (UMCH-V)
Impact factor: 4.8, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.jbc.2024.107325
Permanent Link: https://hdl.handle.net/11104/0353904File Download Size Commentary Version Access 10.1016j.jbc.2024.107325.pdf 0 1.6 MB Publisher’s postprint open-access - 2.0547609 - ÚOCHB 2022 RIV US eng J - Journal Article
Blažková, Kristýna - Beranová, Jana - Hradilek, Martin - Kostka, Libor - Šubr, Vladimír - Etrych, Tomáš - Šácha, Pavel - Konvalinka, Jan
The Development of a High-Affinity Conformation-Sensitive Antibody Mimetic Using a Biocompatible Copolymer Carrier (iBody).
Journal of Biological Chemistry. Roč. 297, č. 5 (2021), č. článku 101342. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR(CZ) GA21-04166S; GA ČR(CZ) GA19-05649S; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963 ; RVO:61389013
Keywords : antibody mimetics * bicyclic phage display * molecular recognition * HPMA copolymer * PSMA * phage display * cyclic peptide * protein targeting * nanotechnology * chemical biology
OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V)
Impact factor: 5.485, year: 2021
Method of publishing: Open access
https://doi.org/10.1016/j.jbc.2021.101342
Permanent Link: http://hdl.handle.net/11104/0323818 - 3.0499970 - ÚOCHB 2019 RIV US eng J - Journal Article
Šimon, Petr - Knedlík, Tomáš - Blažková, Kristýna - Dvořáková, Petra - Březinová, Anna - Kostka, Libor - Šubr, Vladimír - Konvalinka, Jan - Šácha, Pavel
Identification of Protein Targets of Bioactive Small Molecules Using Randomly Photomodified Probes.
ACS Chemical Biology. Roč. 13, č. 12 (2018), s. 3333-3342. ISSN 1554-8929. E-ISSN 1554-8937
R&D Projects: GA ČR(CZ) GA16-02938S; GA MŠMT LO1302; GA MZd(CZ) NV15-31379A
Institutional support: RVO:61388963 ; RVO:61389013
Keywords : glutamate carboxypeptidase II * inhibitor * design
OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V)
Impact factor: 4.374, year: 2018
Permanent Link: http://hdl.handle.net/11104/0292149