Search results

  1. 1.
    0511337 - ÚMG 2020 RIV US eng J - Journal Article
    Courtney, A. H. - Shvets, A. A. - Lu, W. - Griffante, G. - Mollenauer, M. - Horková, Veronika - Lo, W.L. - Yu, S. - Štěpánek, Ondřej - Chakraborty, A. K. - Weiss, A.
    CD45 functions as a signaling gatekeeper in T cells.
    Science Signaling. Roč. 12, č. 604 (2019), č. článku aaw8151. ISSN 1945-0877. E-ISSN 1937-9145
    R&D Projects: GA ČR GJ16-09208Y
    Institutional support: RVO:68378050
    Keywords : tyrosine protein-kinase * src-family kinases * antigen receptor * structural basis * b-cells * lck * activation * tcr * phosphatase * initiation
    OECD category: Immunology
    Impact factor: 6.467, year: 2019
    Method of publishing: Limited access
    https://stke.sciencemag.org/content/12/604/eaaw8151
    Permanent Link: http://hdl.handle.net/11104/0306728
     
     
  2. 2.
    0502272 - ÚMG 2019 RIV NL eng J - Journal Article
    Přibíková, Michaela - Moudrá, Alena - Štěpánek, Ondřej
    Opinion: Virtual memory CD8 T cells and lymphopenia-induced memory CD8 T cells represent a single subset: Homeostatic memory T cells.
    Immunology Letters. Roč. 203, November (2018), s. 57-61. ISSN 0165-2478. E-ISSN 1879-0542
    R&D Projects: GA ČR GJ16-09208Y
    Institutional support: RVO:68378050
    Keywords : tcr * T cell * Drcl/Ccdc164 * Lymphopenia * Virtual memory * Homeostatic memory
    OECD category: Immunology
    Impact factor: 2.552, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0294219
     
     
  3. 3.
    0495610 - ÚMG 2019 RIV GB eng J - Journal Article
    Drobek, Aleš - Moudrá, Alena - Mueller, D. - Huranová, Martina - Horková, Veronika - Přibíková, Michaela - Ivánek, R. - Zehn, D. - Oberle, S. - McCoy, K.D. - Dráber, Peter - Štěpánek, Ondřej
    Strong homeostatic TCR signals induce formation of self-tolerant virtual memory CD8 T cells.
    EMBO Journal. Roč. 37, č. 14 (2018), č. článku e98518. ISSN 0261-4189. E-ISSN 1460-2075
    R&D Projects: GA ČR GJ16-09208Y; GA MŠMT(CZ) LM2015040; GA MŠMT ED2.1.00/19.0395; GA MŠMT(CZ) ED1.1.00/02.0109
    Institutional support: RVO:68378050
    Keywords : gene expression profiling of T-cell subsets * retrogenic T cell * self-reactivity * T-cell receptor repertoire * virtual memory T cells
    OECD category: Immunology
    Impact factor: 11.227, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0288552
    FileDownloadSizeCommentaryVersionAccess
    EMBO_Journal_A_Drobek_2018.pdf13.2 MBAuthor´s preprintrequire
     
     
  4. 4.
    0495490 - ÚMG 2019 RIV US eng J - Journal Article
    Lo, W.L. - Shah, N.H. - Ahsan, N. - Horková, Veronika - Štěpánek, Ondřej - Salomon, A. R. - Kuriyan, J. - Weiss, A.
    Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT.
    Nature Immunology. Roč. 19, č. 7 (2018), s. 733-741. ISSN 1529-2908. E-ISSN 1529-2916
    R&D Projects: GA ČR GJ16-09208Y
    Institutional support: RVO:68378050
    Keywords : t-cell-receptor * phosphotyrosine-binding domain * lymphoproliferative disease * thymocyte development * structural basis * sh2 domain * in-vivo * activation * zap-70 * association
    OECD category: Immunology
    Impact factor: 23.530, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0288463
     
     
  5. 5.
    0477930 - ÚMG 2018 RIV NL eng J - Journal Article
    Bosch, A.J.T. - Bolinger, B. - Keck, S. - Štěpánek, Ondřej - Ozga, A.J. - Galati-Fournier, V. - Stein, J.V. - Palmer, E.
    A minimum number of autoimmune T cells to induce autoimmunity?
    Cellular Immunology. Roč. 316, jaro (2017), s. 21-31. ISSN 0008-8749. E-ISSN 1090-2163
    R&D Projects: GA ČR GJ16-09208Y
    Institutional support: RVO:68378050
    Keywords : T cell * Tolerance * Autoimmunity
    OECD category: Immunology
    Impact factor: 2.995, year: 2017
    Permanent Link: http://hdl.handle.net/11104/0274142
     
     
  6. 6.
    0473101 - ÚMG 2017 RIV US eng J - Journal Article
    Palmer, E. - Drobek, Aleš - Štěpánek, Ondřej
    Opposing effects of actin signaling and LFA-1 on establishing the affinity threshold for inducing effector T-cell responses in mice.
    European Journal of Immunology. Roč. 46, č. 8 (2016), s. 1887-1901. ISSN 0014-2980. E-ISSN 1521-4141
    R&D Projects: GA ČR GJ16-09208Y
    Institutional support: RVO:68378050
    Keywords : Actin cytoskeleton * Antigen affinity treshold * LFA-1 * Rap1 * Rho-family GTPases * T-cell receptor signaling
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 4.227, year: 2016
    Permanent Link: http://hdl.handle.net/11104/0270266
    FileDownloadSizeCommentaryVersionAccess
    European_Journal_of_immunology_E_Palmer_2016.pdf22.9 MBAuthor’s postprintrequire
     
     
  7. 7.
    0473098 - ÚMG 2017 RIV US eng J - Journal Article
    Huranová, Martina - Štěpánek, Ondřej
    Role of actin cytoskeleton at multiple levels of T cell activation.
    AIMS Molecular Science. Roč. 3, č. 4 (2016), s. 585-596. ISSN 2372-0301
    R&D Projects: GA ČR GJ16-09208Y
    Institutional support: RVO:68378050
    Keywords : T cell * actin * cytoskeleton * TCR * signal transduction * antigen recognition * antigen affinity threshold * immunological synapse
    Subject RIV: EB - Genetics ; Molecular Biology
    Permanent Link: http://hdl.handle.net/11104/0270261
     
     
  8. 8.
    0473093 - ÚMG 2017 RIV US eng J - Journal Article
    Hrdinka, M. - Sudan, K. - Just, S. - Drobek, Aleš - Štěpánek, Ondřej - Schlueter, D. - Reinhold, D. - Jordan, B.A. - Gintschel, P. - Schraven, B. - Kreutz, M.R.
    Normal Development and Function of T Cells in Proline Rich 7 (Prr7) Deficient Mice.
    PLoS ONE. Roč. 11, č. 9 (2016), č. článku e0162863. ISSN 1932-6203. E-ISSN 1932-6203
    R&D Projects: GA ČR GJ16-09208Y
    Institutional support: RVO:68378050
    Keywords : transmembrane adapter proteins * experimental autoimmune encephalomyelitis * multiple-sclerosis * listeria-monocytogenes * lymphocyte development * negative regulation * activation * receptor * neurodegeneration * apoptosis
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 2.806, year: 2016
    Permanent Link: http://hdl.handle.net/11104/0270257
     
     


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