Search results
- 1.0511902 - FGÚ 2020 RIV NL eng J - Journal Article
Kaniaková, Martina - Nepovímová, E. - Kletečková, L. - Skřenková, K. - Holubová, K. - Chrienová, Z. - Hepnarová, V. - Kučera, T. - Kobrlová, T. - Valeš, K. - Korábečný, J. - Soukup, O. - Horák, Martin
Combination of Memantine and 6-Chlorotacrine as Novel Multi-Target Compound against Alzheimer's Disease.
Current Alzheimer Research. Roč. 16, č. 9 (2019), s. 821-833. ISSN 1567-2050. E-ISSN 1875-5828
R&D Projects: GA ČR(CZ) GA16-08554S
Institutional support: RVO:67985823
Keywords : 6-Chlorotacrine * Alzheimer´s disease * NMDA receptor * acetylcholinesterase * ion channel * memantine * patch-clamp technique
OECD category: Neurosciences (including psychophysiology
Impact factor: 3.047, year: 2019
Method of publishing: Limited access
http://www.eurekaselect.com/170309/article
Permanent Link: http://hdl.handle.net/11104/0302140 - 2.0495300 - FGÚ 2019 RIV NL eng J - Journal Article
Kaniaková, Martina - Kletečková, Lenka - Lichnerová, Katarina - Holubová, Kristína - Skřenková, K. - Kořínek, Miloslav - Krůšek, Jan - Smejkalová, Tereza - Korábečný, J. - Valeš, Karel - Soukup, O. - Horák, Martin
7-Methoxyderivative of tacrine is a 'foot-in-the-door' open-channel blocker of GluN1/GluN2 and GluN1/GluN3 NMDA receptors with neuroprotective activity in vivo.
Neuropharmacology. Roč. 140, Sep 15 (2018), s. 217-232. ISSN 0028-3908. E-ISSN 1873-7064
R&D Projects: GA ČR(CZ) GA16-08554S
Institutional support: RVO:67985823
Keywords : behavioural experiment * electrophysiology * glutamate receptor * human pathogenic mutation * ion channel * pharmacology
OECD category: Neurosciences (including psychophysiology
Impact factor: 4.367, year: 2018
Permanent Link: http://hdl.handle.net/11104/0288296 - 3.0474134 - FGÚ 2018 RIV US eng J - Journal Article
Horák, Martin - Holubová, K. - Nepovímová, E. - Krůšek, Jan - Kaniaková, Martina - Korábečný, J. - Vyklický ml., Ladislav - Kuča, K. - Stuchlík, Aleš - Říčný, J. - Valeš, K. - Soukup, O.
The pharmacology of tacrine at N-methyl-D-aspartate receptors.
Progress in Neuro-Psychopharmacology & Biological Psychiatry. Roč. 75, Apr 3 (2017), s. 54-62. ISSN 0278-5846. E-ISSN 1878-4216
R&D Projects: GA ČR(CZ) GA16-08554S
Institutional support: RVO:67985823
Keywords : tacrine * NMDA receptors * long term potentiation * cognition * M1 activation * multi-target directed ligands
OECD category: Neurosciences (including psychophysiology
Impact factor: 4.185, year: 2017
Permanent Link: http://hdl.handle.net/11104/0271246 - 4.0474014 - FGÚ 2018 RIV NL eng J - Journal Article
Gažová, Z. - Soukup, O. - Šepsová, V. - Šipošová, K. - Drtinová, L. - Jošt, P. - Spilovská, K. - Korábečný, J. - Nepovímová, E. - Fedunová, D. - Horák, Martin - Kaniaková, Martina - Wang, Z. J. - Hamouda, A. K. - Kuča, K.
Multi-target-directed therapeutic potential of 7-methoxytacrine-adamantylamine heterodimers in the Alzheimer's disease treatment.
Biochimica Et Biophysica Acta-Molecular Basis of Disease. Roč. 1863, č. 2 (2017), s. 607-619. ISSN 0925-4439. E-ISSN 1879-260X
R&D Projects: GA ČR(CZ) GA16-08554S
Institutional support: RVO:67985823
Keywords : amyloid * aggregation * muscarinic/nicotinic acetylcholine receptor antagonist * N-Methyl-d-aspartate receptor antagonist * Alzheimer's disease * A beta peptide * beta-secretase inhibitor
OECD category: Neurosciences (including psychophysiology
Impact factor: 5.108, year: 2017
Permanent Link: http://hdl.handle.net/11104/0271109