Search results
- 1.0532352 - FGÚ 2021 RIV US eng J - Journal Article
Plecitá-Hlavatá, Lydie - Engstová, Hana - Holendová, Blanka - Tauber, Jan - Špaček, Tomáš - Petrásková, Lucie - Křen, Vladimír - Špačková, Jitka - Gotvaldová, Klára - Ježek, Jan - Dlasková, Andrea - Smolková, Katarína - Ježek, Petr
Mitochondrial Superoxide Production Decreases on Glucose-Stimulated Insulin Secretion in Pancreatic beta Cells Due to Decreasing Mitochondrial Matrix NADH/NAD(+) Ratio.
Antioxidants & Redox Signaling. Roč. 33, č. 12 (2020), s. 789-815. ISSN 1523-0864. E-ISSN 1557-7716
R&D Projects: GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S; GA ČR(CZ) GA20-00408S
Institutional support: RVO:67985823 ; RVO:61388971
Keywords : mitochondrial superoxide generation * pancreatic beta cells * glucose-stimulated insulin secretion * Complex I * NADH/NAD(+) ratio * fluorescence lifetime imaging
OECD category: Endocrinology and metabolism (including diabetes, hormones); Analytical chemistry (MBU-M)
Impact factor: 8.401, year: 2020
Method of publishing: Open access
https://www.liebertpub.com/doi/10.1089/ars.2019.7800
Permanent Link: http://hdl.handle.net/11104/0310854 - 2.0531109 - FGÚ 2021 RIV US eng J - Journal Article
Plecitá-Hlavatá, Lydie - Jabůrek, Martin - Holendová, Blanka - Tauber, Jan - Pavluch, Vojtěch - Berková, Z. - Cahová, M. - Schröder, K. - Brandes, R. P. - Siemen, D. - Ježek, Petr
Glucose-Stimulated Insulin Secretion Fundamentally Requires H(2)O(2)Signaling by NADPH Oxidase 4.
Diabetes. Roč. 69, č. 7 (2020), s. 1341-1354. ISSN 0012-1797. E-ISSN 1939-327X
R&D Projects: GA ČR(CZ) GA20-00408S; GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S
Institutional support: RVO:67985823
Keywords : glucose-stimulated insulin secretion * NADPH oxidase NOX4 * ATP-sensitive potassium channel * cytosolic H2O2 redox signaling * beta-cell-specific NOX4 knockout mice * 2-oxo-isocaproate
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 9.461, year: 2020
Method of publishing: Open access
https://doi.org/10.2337/db19-1130
Permanent Link: http://hdl.handle.net/11104/0309847 - 3.0510404 - FGÚ 2020 RIV US eng J - Journal Article
Ježek, Petr - Jabůrek, Martin - Plecitá-Hlavatá, Lydie
Contribution of Oxidative Stress and Impaired Biogenesis of Pancreatic beta-Cells to Type 2 Diabetes.
Antioxidants & Redox Signaling. Roč. 31, č. 10 (2019), s. 722-751. ISSN 1523-0864. E-ISSN 1557-7716
R&D Projects: GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S
Institutional support: RVO:67985823
Keywords : pancreatic beta-cells * type 2 diabetes * oxidative stress * impaired redox signaling * beta-cell identity self-checking * dedifferentiation
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 7.040, year: 2019
Method of publishing: Open access
https://doi.org/10.1089/ars.2018.7656
Permanent Link: http://hdl.handle.net/11104/0300914 - 4.0506716 - FGÚ 2020 RIV US eng J - Journal Article
Plecitá-Hlavatá, Lydie - Engstová, Hana - Ježek, Jan - Holendová, Blanka - Tauber, Jan - Petrásková, Lucie - Křen, Vladimír - Ježek, Petr
Potential of Mitochondria-Targeted Antioxidants to Prevent Oxidative Stress in Pancreatic beta-cells.
Oxidative Medicine and Cellular Longevity. Roč. 2019, č. 2019 (2019), č. článku 1826303. ISSN 1942-0900. E-ISSN 1942-0994
R&D Projects: GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S; GA ČR(CZ) GA18-00121S
Institutional support: RVO:67985823 ; RVO:61388971
Keywords : pancreatic beta cells * pancreatic islets * mitochondria- targeted antioxidants * oxidative stress * SkQ * S3QEL * S1QEL
OECD category: Cell biology; Physiology (including cytology) (MBU-M)
Impact factor: 5.076, year: 2019
Method of publishing: Open access
https://doi.org/10.1155/2019/1826303
Permanent Link: http://hdl.handle.net/11104/0297909 - 5.0493406 - FGÚ 2019 RIV CH eng J - Journal Article
Ježek, Petr - Jabůrek, Martin - Holendová, Blanka - Plecitá-Hlavatá, Lydie
Fatty Acid-Stimulated Insulin Secretion vs. Lipotoxicity.
Molecules. Roč. 23, č. 6 (2018), č. článku 1483. E-ISSN 1420-3049
R&D Projects: GA ČR(CZ) GA16-06700S
Institutional support: RVO:67985823
Keywords : fatty acids * fatty acid-stimulated insulin secretion * GPR40 * pancreatic beta-cells * oxidative stress * lipotoxicity * type 2 diabetes * low-grade inflammation
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 3.060, year: 2018
Permanent Link: http://hdl.handle.net/11104/0286770 - 6.0493403 - FGÚ 2019 RIV NL eng J - Journal Article
Dlasková, Andrea - Engstová, Hana - Špaček, Tomáš - Kahancová, Anežka - Pavluch, Vojtěch - Smolková, Katarína - Špačková, Jitka - Bartoš, Martin - Plecitá-Hlavatá, Lydie - Ježek, Petr
3D super-resolution microscopy reflects mitochondrial cristae alternations and mtDNA nucleoid size and distribution.
Biochimica Et Biophysica Acta-Bioenergetics. Roč. 1859, č. 9 (2018), s. 829-844. ISSN 0005-2728. E-ISSN 1879-2650
R&D Projects: GA ČR(CZ) GA17-08565S; GA ČR(CZ) GJ15-02022Y; GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA16-04788S
Institutional support: RVO:67985823
Keywords : 3D super-resolution microscopy * Ripley's K-function * distances frequency distribution histogram * mitochondrial cristae ATP-synthase alpha subunit * mitochondrial nucleoids
OECD category: Physiology (including cytology)
Impact factor: 4.441, year: 2018
Permanent Link: http://hdl.handle.net/11104/0286764 - 7.0463353 - FGÚ 2017 RIV GB eng J - Journal Article
Plecitá-Hlavatá, Lydie - Ježek, Petr
Integration of superoxide formation and cristae morphology for mitochondrial redox signaling.
International Journal of Biochemistry and Cell Biology. Roč. 80, Nov (2016), s. 31-50. ISSN 1357-2725. E-ISSN 1878-5875
R&D Projects: GA ČR(CZ) GA16-04788S; GA ČR(CZ) GA16-06700S
Institutional support: RVO:67985823
Keywords : redox signaling * mitochondrial cristae morphology * ATP-synthase dimers * OPA1 * MICOS
Subject RIV: EA - Cell Biology
Impact factor: 3.505, year: 2016
Permanent Link: http://hdl.handle.net/11104/0262557