Search results
- 1.0587139 - ÚOCHB 2025 RIV US eng J - Journal Article
Chayka, Artem - Česnek, Michal - Kužmová, Erika - Kozák, Jaroslav - Tloušťová, Eva - Dvořáková, Alexandra - Strmeň, Timotej - Brož, Břetislav - Osifová, Zuzana - Dračínský, Martin - Mertlíková-Kaiserová, Helena - Janeba, Zlatko
Structure-Based Drug Design of ADRA2A Antagonists Derived from Yohimbine.
Journal of Medicinal Chemistry. (2024). ISSN 0022-2623. E-ISSN 1520-4804
Institutional support: RVO:61388963
Keywords : receptors * serotonin * alpha(2)-adrenoceptors
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acs.jmedchem.4c00323
Permanent Link: https://hdl.handle.net/11104/0354415
Research data: PDB Worldwide - 2.0574366 - ÚOCHB 2024 RIV US eng J - Journal Article
Břehová, Petra - Řezníčková, E. - Škach, Kryštof - Jorda, R. - Dejmek, Milan - Vojáčková, V. - Šála, Michal - Kovalová, M. - Dračínský, Martin - Dolníková, A. - Strmeň, Timotej - Kinnertová, M. - Chalupský, Karel - Dvořáková, Alexandra - Gucký, T. - Mertlíková-Kaiserová, Helena - Klener, P. - Nencka, Radim - Kryštof, V.
Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2-b]pyridazine Derivatives Identified by Scaffold Hopping.
Journal of Medicinal Chemistry. Roč. 66, č. 16 (2023), s. 11133-11157. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MZd(CZ) NU20-05-00472; GA MŠMT LX22NPO5102
Institutional support: RVO:61388963
Keywords : gene expression * highly potent
OECD category: Oncology
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acs.jmedchem.3c00575
Permanent Link: https://hdl.handle.net/11104/0344703File Download Size Commentary Version Access 10.1021acs.jmedchem.3c00575.pdf 1 7.8 MB Publisher’s postprint open-access - 3.0569878 - ÚOCHB 2024 RIV US eng J - Journal Article
Kloudová, Barbora - Strmeň, Timotej - Vrkoslav, Vladimír - Chára, Zdeněk - Pačes, Ondřej - Cvačka, Josef
Gas Dynamic Virtual Nozzle Sprayer for an Introduction of Liquid Samples in Atmospheric Pressure Ionization Mass Spectrometry.
Analytical Chemistry. Roč. 95, č. 8 (2023), s. 4196-4203. ISSN 0003-2700. E-ISSN 1520-6882
R&D Projects: GA ČR(CZ) GA20-09126S
Institutional support: RVO:61388963 ; RVO:67985874
Keywords : droplets * generation * interface
OECD category: Analytical chemistry; Fluids and plasma physics (including surface physics) (UH-J)
Impact factor: 7.4, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acs.analchem.2c05349
Permanent Link: https://hdl.handle.net/11104/0341217 - 4.0563164 - ÚOCHB 2023 RIV NL eng J - Journal Article
Radilová, Kateřina - Zima, Václav - Král, Michal - Machara, Aleš - Majer, Pavel - Hodek, Jan - Weber, Jan - Brynda, Jiří - Strmeň, Timotej - Konvalinka, Jan - Kožíšek, Milan
Thermodynamic and structural characterization of an optimized peptide-based inhibitor of the influenza polymerase PA-PB1 subunit interaction.
Antiviral Research. Roč. 208, December (2022), č. článku 105449. ISSN 0166-3542. E-ISSN 1872-9096
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : antiviral peptides * influenza A polymerase * protein-protein interaction * AlphaScreen * isothermal titration calorimetry
OECD category: Biochemistry and molecular biology
Impact factor: 7.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.antiviral.2022.105449
Permanent Link: https://hdl.handle.net/11104/0335206File Download Size Commentary Version Access 10.1016j.antiviral.2022.105449.pdf 5 6.4 MB Publisher’s postprint open-access - 5.0547506 - ÚOCHB 2022 RIV US eng J - Journal Article
Kalčic, Filip - Zgarbová, Michala - Hodek, Jan - Chalupský, Karel - Dračínský, Martin - Dvořáková, Alexandra - Strmeň, Timotej - Šebestík, Jaroslav - Baszczyňski, Ondřej - Weber, Jan - Mertlíková-Kaiserová, Helena - Janeba, Zlatko
Discovery of Modified Amidate (ProTide) Prodrugs of Tenofovir with Enhanced Antiviral Properties.
Journal of Medicinal Chemistry. Roč. 64, č. 22 (2021), s. 16425-16449. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT LTAUSA18086
Institutional support: RVO:61388963
Keywords : chemistry * drug development * drug effect
OECD category: Organic chemistry
Impact factor: 8.039, year: 2021
Method of publishing: Limited access
https://doi.org/10.1021/acs.jmedchem.1c01444
Permanent Link: http://hdl.handle.net/11104/0323727 - 6.0524555 - ÚOCHB 2021 RIV DE eng J - Journal Article
Vrkoslav, Vladimír - Rumlová, Barbora - Strmeň, Timotej - Cvačka, Josef
Temperature‐programmed capillary high‐performance liquid chromatography with atmospheric pressure chemical ionization mass spectrometry for analysis of fatty acid methyl esters.
Journal of Separation Science. Roč. 43, č. 13 (2020), s. 2579-2588. ISSN 1615-9306. E-ISSN 1615-9314
R&D Projects: GA ČR(CZ) GA16-01639S; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : double bonds * high-performance liquid chromatography * lipidomics * lipids * temperature programming
OECD category: Analytical chemistry
Impact factor: 3.645, year: 2020
Method of publishing: Limited access
https://onlinelibrary.wiley.com/doi/full/10.1002/jssc.201901235
Permanent Link: http://hdl.handle.net/11104/0308895 - 7.0523601 - ÚOCHB 2021 RIV GB eng J - Journal Article
Strmeň, Timotej - Vrkoslav, Vladimír - Bosáková, Z. - Cvačka, Josef
Atmospheric pressure chemical ionization mass spectrometry at low flow rates: Importance of ion source housing.
Rapid Communications in Mass Spectrometry. Roč. 34, č. 10 (2020), č. článku e8722. ISSN 0951-4198. E-ISSN 1097-0231
R&D Projects: GA ČR(CZ) GA16-01639S
Institutional support: RVO:61388963
Keywords : chemical ionization * gas-phase reactions * ion source design
OECD category: Analytical chemistry
Impact factor: 2.419, year: 2020
Method of publishing: Limited access
https://onlinelibrary.wiley.com/doi/full/10.1002/rcm.8722
Permanent Link: http://hdl.handle.net/11104/0307927 - 8.0490859 - ÚOCHB 2019 RIV AT eng J - Journal Article
Strmeň, Timotej - Vrkoslav, Vladimír - Pačes, Ondřej - Cvačka, Josef
Evaluation of an ion source with a tubular nebulizer for microflow atmospheric pressure chemical ionization.
Monatshefte fur Chemie. Roč. 149, č. 6 (2018), s. 987-994. ISSN 0026-9247. E-ISSN 1434-4475
R&D Projects: GA ČR(CZ) GA16-01639S
Institutional support: RVO:61388963
Keywords : charge transfer * hydrogen transfer * mass spectroscopy * micro-APCI * tubular nebulizer
OECD category: Analytical chemistry
Impact factor: 1.501, year: 2018
Permanent Link: http://hdl.handle.net/11104/0284992 - 9.0489841 - ÚOCHB 2019 RIV GB eng J - Journal Article
Vrkoslav, Vladimír - Rumlová, B. - Strmeň, Timotej - Nekvasilová, P. - Šulc, M. - Cvačka, Josef
Applicability of low-flow atmospheric pressure chemical ionization and photoionization mass spectrometry with a microfabricated nebulizer for neutral lipids.
Rapid Communications in Mass Spectrometry. Roč. 32, č. 8 (2018), s. 639-648. ISSN 0951-4198. E-ISSN 1097-0231
R&D Projects: GA ČR(CZ) GA16-01639S
Institutional support: RVO:61388963
Keywords : capillary liquid chromatography * vernix caseosa * fatty acid
OECD category: Analytical chemistry
Impact factor: 2.045, year: 2018
Permanent Link: http://hdl.handle.net/11104/0284174