Search results
- 1.0568179 - ÚOCHB 2023 GB eng A - Abstract
Brynda, Jiří - Kugler, Michael - Nekvinda, Jan - Holub, Josef - El Anwar, Suzan - Das, V. - Šícha, Václav - Pospíšilová, Klára - Fábry, Milan - Král, Vlastimil - Pachl, Petr - Hajdúch, M. - Grüner, Bohumír - Řezáčová, Pavlína
Structure-assisted design of inhibitors of CA IX enzyme based on polyhedral boron compounds.
Acta Crystallographica Section A-Foundation and Advances. Oxford Blackwell. Roč. 77 (2021), C864-C864. ISSN 2053-2733. E-ISSN 2053-2733
Institutional support: RVO:61388963 ; RVO:61388980 ; RVO:68378050
Keywords : carborane * cobal bis(dicarbollide) * carbonic anhydrase * enzyme inhibition * SAR study
https://journals.iucr.org/a/issues/2021/a2/00/a60441/a60441.pdf
Permanent Link: https://hdl.handle.net/11104/0339514 - 2.0520890 - ÚOCHB 2020 GB eng A - Abstract
Řezáčová, Pavlína - Kugler, Michael - Brynda, Jiří - Grüner, Bohumír - Hajdúch, M. - Nekvinda, Jan - Pospíšilová, Klára - Das, V. - Holub, Josef
Structure-assisted design of Carborane inhibitors of human Carbonic anhydrase IX.
Acta Crystallographica Section A-Foundation and Advances. Oxford Blackwell. Roč. 74, Suppl (2018), „e197“. ISSN 2053-2733. E-ISSN 2053-2733.
[European Crystallography Meeting /31./. 22.08.2018-27.08.2018, Oviedo]
R&D Projects: GA ČR(CZ) GA15-05677S; GA TA ČR(CZ) TE01020028; GA MŠMT(CZ) LO1304; GA MŠMT(CZ) LM2015064
Institutional support: RVO:61388963 ; RVO:68378050 ; RVO:61388980
Keywords : anti-tumor agents * carborane inhibitors * Carbonic anhydrase IX
OECD category: Biochemistry and molecular biology; Inorganic and nuclear chemistry (UACH-T)
Permanent Link: http://hdl.handle.net/11104/0305557 - 3.0468476 - ÚOCHB 2017 US eng A - Abstract
Agrawal, K. - Das, V. - Otmar, Miroslav - Krečmerová, Marcela - Džubák, P. - Hajdúch, M.
Cell-based DNA demethylation detection system for screening of epigenetic drugs in 2D, 3D and xenograft models.
Molecular Cancer Therapeutics. American Association for Cancer Research. Roč. 14, Suppl 2 (2015), B72. ISSN 1535-7163. E-ISSN 1538-8514.
[AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics. 05.11.2015-09.11.2015, Boston]
R&D Projects: GA MPO(CZ) FR-TI4/625; GA MŠMT(CZ) LO1304
Institutional support: RVO:61388963
Keywords : demethylation * epigenetic drugs * fluorescence detection system
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0266318 - 4.0459480 - ÚOCHB 2017 US eng A - Abstract
Štěpánková, J. - Řezáčová, Pavlína - Brynda, Jiří - Harvanová, M. - Mašek, V. - Nová, A. - Siller, M. - Das, V. - Doležal, D. - Grüner, Bohumír - Šícha, Václav - Konečný, P. - Znojek, P. - Džubák, P. - Hajdúch, M.
Novel carborane based inhibitors of carbonic anhydrase IX.
Cancer Research. American Association for Cancer Research. Roč. 75, 15 Suppl (2015), s. 4492. ISSN 0008-5472. E-ISSN 1538-7445.
[Annual Meeting of the American Association for Cancer Research (AACR) /106./. 18.04.2015-22.04.2015, Philadelphia]
Institutional support: RVO:61388963 ; RVO:61388980
Keywords : carbonic anhydrase * carborane based inhibitors
Subject RIV: CE - Biochemistry
Permanent Link: http://hdl.handle.net/11104/0259668