Search results
- 1.0556294 - ÚMG 2022 RIV CH eng J - Journal Article
Reiberger, R. - Radilova, K. - Král, M. - Zima, V. - Majer, P. - Brynda, Jiří - Dračínský, M. - Konvalinka, J. - Kožíšek, M. - Machara, A.
Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors.
International Journal of Molecular Sciences. Roč. 22, č. 14 (2021), č. článku 7735. E-ISSN 1422-0067
Institutional support: RVO:68378050
Keywords : bio-isosterism * cross-coupling * endonuclease inhibitor * flavonoids * influenza * Mannich reaction * RNA polymerase
OECD category: Biochemistry and molecular biology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1422-0067/22/14/7735
Permanent Link: http://hdl.handle.net/11104/0330581 - 2.0554896 - BTÚ 2022 RIV US eng J - Journal Article
Vavrina, Z. - Gutten, O. - Smola, M. - Zavrel, M. - Tehrani, Zahra Aliakbar - Charvat, V. - Kožíšek, M. - Bouřa, E. - Birkus, G. - Rulíšek, L.
Protein-Ligand Interactions in the STING Binding Site Probed by Rationally Designed Single-Point Mutations: Experiment and Theory.
Biochemistry. Roč. 60, č. 8 (2021), s. 607-620. ISSN 0006-2960
Institutional support: RVO:86652036
Keywords : cyclic di-gmp * interferon genes * dna sensor * dinucleotide
OECD category: Biochemistry and molecular biology
Impact factor: 3.321, year: 2021
Method of publishing: Limited access
https://pubs.acs.org/doi/10.1021/acs.biochem.0c00949
Permanent Link: http://hdl.handle.net/11104/0329535 - 3.0544819 - ÚMG 2022 RIV NL eng J - Journal Article
Hejdanek, J. - Radilova, K. - Pachl, P. - Hodek, J. - Machara, A. - Weber, J. - Řezáčová, Pavlína - Konvalinka, J. - Kožíšek, M.
structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor.
Antiviral Research. Roč. 185, January (2021), č. článku 104971. ISSN 0166-3542. E-ISSN 1872-9096
Institutional support: RVO:68378050
Keywords : Antiviral peptides * Influenza a polymerase * Protein-protein interaction * AlphaScreen
OECD category: Pharmacology and pharmacy
Impact factor: 10.103, year: 2021
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0166354220303855?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0321625 - 4.0539161 - ÚMG 2021 RIV FR eng J - Journal Article
Zima, V. - Radilova, K. - Kožíšek, M. - Albinana, C. B. - Karlukova, E. - Brynda, Jiří - Fanfrlik, J. - Flieger, M. - Hodek, J. - Weber, J. - Majer, P. - Konvalinka, J. - Machara, A.
Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors.
European Journal of Medicinal Chemistry. Roč. 208, December (2020), č. článku 112754. ISSN 0223-5234. E-ISSN 1768-3254
Institutional support: RVO:68378050
Keywords : Influenza * Neuraminidase * Polyphenols * PA(N) endonuclease Inhibitors * RNA polymerase
OECD category: Biochemistry and molecular biology
Impact factor: 6.514, year: 2020
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0223523420307261?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0316866 - 5.0522874 - ÚMG 2020 RIV GB eng J - Journal Article
Zima, V. - Albinana, C. B. - Rojíková, K. - Pokorná, J. - Pachl, P. - Řezáčová, Pavlína - Hudlický, J. - Navrátil, V. - Majer, P. - Konvalinka, J. - Kožíšek, M. - Machara, A.
Investigation of flexibility of neuraminidase 150-loop using tamiflu derivatives in influenza A viruses H1N1 and H5N1.
Bioorganic & Medicinal Chemistry. Roč. 27, č. 13 (2019), s. 2935-2947. ISSN 0968-0896. E-ISSN 1464-3391
Institutional support: RVO:68378050
Keywords : Influenza neuraminidase * Oseltamivir * Click chemistry * Crystal structure
OECD category: Cell biology
Impact factor: 3.073, year: 2019
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0968089619305358?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0307288 - 6.0503521 - ÚMG 2019 RIV GB eng J - Journal Article
Kožíšek, M. - Navrátil, V. - Rojíková, K. - Pokorná, J. - Albinana, C. B. - Pachl, P. - Zemanová, J. - Machara, A. - Šácha, P. - Hudlický, J. - Císařová, I. - Řezáčová, Pavlína - Konvalinka, J.
DNA-linked inhibitor antibody assay (DIANA) as a new method for screening influenza neuraminidase inhibitors.
Biochemical Journal. Roč. 475, č. 23 (2018), s. 3847-3860. ISSN 0264-6021. E-ISSN 1470-8728
Institutional support: RVO:68378050
Keywords : DNA-linked inhibitor antibody assay (DIANA) * influenza neuraminidase * inhibition constant
OECD category: Biochemistry and molecular biology
Impact factor: 4.331, year: 2018
Permanent Link: http://hdl.handle.net/11104/0295338 - 7.0495122 - ÚMG 2019 RIV CH eng J - Journal Article
Pokorná, J. - Pachl, P. - Karkulková, E. - Hejdanek, J. - Řezáčová, Pavlína - Machara, A. - Hudlický, J. - Konvalinka, J. - Kožíšek, M.
Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza Virus.
Viruses. Roč. 10, č. 7 (2018), č. článku 339. E-ISSN 1999-4915
Institutional support: RVO:68378050
Keywords : influenza neuraminidase * resistance * oseltamivir * isothermal titration calorimetry * crystal structure
OECD category: Biochemistry and molecular biology
Impact factor: 3.811, year: 2018
Permanent Link: http://hdl.handle.net/11104/0288133 - 8.0473216 - ÚMG 2017 RIV FR eng J - Journal Article
Albinana, C. B. - Machara, A. - Řezáčová, Pavlína - Pachl, P. - Konvalinka, J. - Kožíšek, M.
Kinetic, thermodynamic and structural analysis of tamiphosphor binding to neuraminidase of H1N1 (2009) pandemic influenza.
European Journal of Medicinal Chemistry. Roč. 121, OCT 4 (2016), s. 100-109. ISSN 0223-5234. E-ISSN 1768-3254
Institutional support: RVO:68378050
Keywords : Influenza neuraminidase * Oseltamivir * Tamiphosphor * Isothermal titration calorimetry * Crystal structure * Lattice-translocation defect
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 4.519, year: 2016
Permanent Link: http://hdl.handle.net/11104/0270375