Search results
- 1.0532766 - ÚOCHB 2021 RIV DE eng J - Journal Article
Veselovská, Lucia - Kudlová, N. - Gurská, S. - Lišková, B. - Medvedíková, M. - Hodek, Ondřej - Tloušťová, Eva - Milisavljevič, Nemanja - Tichý, Michal - Perlíková, Pavla - Mertlíková-Kaiserová, Helena - Trylčová, Jana - Pohl, Radek - Klepetářová, Blanka - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis and Cytotoxic and Antiviral Activity Profiling of All-Four Isomeric Series of Pyrido-Fused 7-Deazapurine Ribonucleosides.
Chemistry - A European Journal. Roč. 26, č. 57 (2020), s. 13002-13015. ISSN 0947-6539. E-ISSN 1521-3765
R&D Projects: GA ČR(CZ) GA19-08124S; GA MZd(CZ) NV15-31984A; GA MŠMT(CZ) LM2015064
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : antitumor agents * antiviral agents * drug discovery * phosphorylation * ribonucleosides
OECD category: Organic chemistry
Impact factor: 5.236, year: 2020
Method of publishing: Limited access
https://doi.org/10.1002/chem.202001124
Permanent Link: http://hdl.handle.net/11104/0311179 - 2.0532387 - ÚOCHB 2021 RIV US eng J - Journal Article
Fleuti, Marianne - Bártová, Kateřina - Poštová Slavětínská, Lenka - Tloušťová, Eva - Tichý, Michal - Gurská, S. - Pavliš, P. - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis and Biological Profiling of Pyrazolo-Fused 7-Deazapurine Nucleosides.
Journal of Organic Chemistry. Roč. 85, č. 16 (2020), s. 10539-10551. ISSN 0022-3263. E-ISSN 1520-6904
R&D Projects: GA ČR(CZ) GA19-08124S; GA MZd(CZ) NV15-31984A; GA MŠMT(CZ) LM2015064
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : tyrosine kinase * inhibitors * adenosine
OECD category: Organic chemistry
Impact factor: 4.354, year: 2020
Method of publishing: Limited access
https://doi.org/10.1021/acs.joc.0c00928
Permanent Link: http://hdl.handle.net/11104/0310889 - 3.0531532 - ÚOCHB 2021 RIV US eng J - Journal Article
Yang, Chao - Pohl, Radek - Tichý, Michal - Gurská, S. - Pavliš, P. - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis, Photophysical Properties, and Biological Profiling of Benzothieno-Fused 7-Deazapurine Ribonucleosides.
Journal of Organic Chemistry. Roč. 85, č. 12 (2020), s. 8085-8101. ISSN 0022-3263. E-ISSN 1520-6904
R&D Projects: GA ČR(CZ) GA19-08124S; GA MZd(CZ) NV15-31984A; GA MŠMT(CZ) LM2015064
Institutional support: RVO:61388963
Keywords : nucleoside * inhibitors * antitumor
OECD category: Organic chemistry
Impact factor: 4.354, year: 2020
Method of publishing: Limited access
https://doi.org/10.1021/acs.joc.0c00927
Permanent Link: http://hdl.handle.net/11104/0310168 - 4.0509096 - ÚOCHB 2020 RIV DE eng J - Journal Article
Malnuit, Vincent - Smolen, Sabina - Tichý, Michal - Poštová Slavětínská, Lenka - Hocek, Michal
Synthesis of Cyclic and Acyclic Nucleoside Phosphonates and Sulfonamides Derived from 6‐(Thiophen‐2‐yl)‐7‐fluoro‐7‐deazapurine.
European Journal of Organic Chemistry. Roč. 2019, 31/32 (2019), s. 5409-5423. ISSN 1434-193X. E-ISSN 1099-0690
R&D Projects: GA ČR(CZ) GA19-08124S; GA MZd(CZ) NV15-31984A
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : 7‐deazapurine * nucleoside phosphonates * structure‐activity relationships * synthetic methods * sulfonamides
OECD category: Organic chemistry
Impact factor: 2.889, year: 2019
Method of publishing: Limited access
https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/ejoc.201900509
Permanent Link: http://hdl.handle.net/11104/0299888 - 5.0480257 - ÚOCHB 2018 RIV DE eng J - Journal Article
Sabat, Nazarii - Smolen, Sabina - Nauš, Petr - Perlíková, Pavla - Cebová, M. - Poštová Slavětínská, Lenka - Hocek, Michal
Synthesis of 2,6-Substituted 7-(Het)aryl-7-deazapurine Nucleobases (2,4-Disubstituted 5-(Het)aryl-pyrrolo[2,3-d]pyrimidines).
Synthesis. Roč. 49, č. 20 (2017), s. 4623-4650. ISSN 0039-7881. E-ISSN 1437-210X
R&D Projects: GA ČR(CZ) GA16-00178S; GA MZd(CZ) NV15-31984A
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : deazapurines * pyrrolo[2,3-d]pyrimidines * nucleobases * Suzuki-Miyaura cross-coupling * deprotection * demethylation
OECD category: Organic chemistry
Impact factor: 2.722, year: 2017
Permanent Link: http://hdl.handle.net/11104/0276103 - 6.0474988 - ÚOCHB 2018 RIV US eng J - Journal Article
Agrawal, K. - Das, V. - Otmar, Miroslav - Krečmerová, Marcela - Džubák, P. - Hajdúch, M.
Cell-based DNA demethylation detection system for screening of epigenetic drugs in 2D, 3D, and xenograft models.
Cytometry. Part A. 91A, č. 2 (2017), s. 133-143. ISSN 1552-4922. E-ISSN 1552-4930
R&D Projects: GA MZd(CZ) NV15-31984A; GA MŠMT(CZ) LO1304; GA MŠMT(CZ) LM2015064; GA TA ČR(CZ) TE01020028
Institutional support: RVO:61388963
Keywords : DNA methylation * DNA methylation inhibitors * demethylation detection system * epigenetic drugs * high content screening
OECD category: Organic chemistry
Impact factor: 3.260, year: 2017
Permanent Link: http://hdl.handle.net/11104/0271874