Search results
- 1.0522693 - ÚOCHB 2021 RIV US eng J - Journal Article
Houštecká, Radka - Hadzima, Martin - Fanfrlík, Jindřich - Brynda, Jiří - Pallová, Lenka - Hánová, Iva - Mertlíková-Kaiserová, Helena - Lepšík, Martin - Horn, Martin - Smrčina, M. - Majer, Pavel - Mareš, Michael
Biomimetic Macrocyclic Inhibitors of Human Cathepsin D: Structure–Activity Relationship and Binding Mode Analysis.
Journal of Medicinal Chemistry. Roč. 63, č. 4 (2020), s. 1576-1596. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA ČR GA15-18929S; GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : inhibitor * macrocycle * protease
OECD category: Biochemistry and molecular biology
Impact factor: 7.446, year: 2020
Method of publishing: Limited access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.9b01351
Permanent Link: http://hdl.handle.net/11104/0307144 - 2.0489934 - ÚOCHB 2019 RIV US eng J - Journal Article
Hánová, Iva - Brynda, Jiří - Houštecká, Radka - Alam, N. - Sojka, Daniel - Kopáček, Petr - Marešová, Lucie - Vondrášek, Jiří - Horn, Martin - Schueler-Furman, O. - Mareš, Michael
Novel Structural Mechanism of Allosteric Regulation of Aspartic Peptidases via an Evolutionarily Conserved Exosite.
Cell Chemical Biology. Roč. 25, č. 3 (2018), s. 318-329. ISSN 2451-9448. E-ISSN 2451-9448
R&D Projects: GA ČR GA15-18929S; GA ČR GA13-11043S; GA MŠMT LO1302; GA ČR GA14-33693S
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : cathepsin D * activation intermediate * crystal structure
OECD category: Biochemistry and molecular biology
Impact factor: 6.762, year: 2018
https://www.sciencedirect.com/science/article/pii/S2451945618300011?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0284232 - 3.0467339 - ÚOCHB 2017 RIV GB eng J - Journal Article
Srp, Jaroslav - Nussbaumerová, Martina - Horn, Martin - Mareš, Michael
Digestive proteolysis in the Colorado potato beetle, Leptinotarsa decemlineata: Activity-based profiling and imaging of a multipeptidase network.
Insect Biochemistry and Molecular Biology. Roč. 78, Nov (2016), s. 1-11. ISSN 0965-1748. E-ISSN 1879-0240
R&D Projects: GA MŠMT LO1302; GA ČR GA15-18929S
Institutional support: RVO:61388963
Keywords : Colorado potato beetle * peptidase * cathepsin * activity-based probe * digestive system * multienzyme network
Subject RIV: CE - Biochemistry
Impact factor: 3.756, year: 2016
Permanent Link: http://hdl.handle.net/11104/0265455 - 4.0455772 - ÚOCHB 2016 RIV US eng J - Journal Article
Guo, J. - Erskine, P. T. - Coker, A. R. - Wood, S. P. - Cooper, J. B. - Mareš, Michael - Baudyš, Miroslav
Structure of a Kunitz-type potato cathepsin D inhibitor.
Journal of Structural Biology. Roč. 192, č. 3 (2015), s. 554-560. ISSN 1047-8477. E-ISSN 1095-8657
R&D Projects: GA ČR GA15-18929S; GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : potato cathepsin D inhibitor * Kunitz-type protease inhibitor * protein X-ray structure * reactive-site loop * docking
Subject RIV: CE - Biochemistry
Impact factor: 2.570, year: 2015
Permanent Link: http://hdl.handle.net/11104/0256395