Search results
- 1.0546864 - FGÚ 2022 RIV US eng J - Journal Article
Dolejší, Eva - Chetverikov, Nikolai - Szánti-Pintér, Eszter - Nelic, Dominik - Randáková, Alena - Doležal, Vladimír - El-Fakahany, E. E. - Kudová, Eva - Jakubík, Jan
Neuroactive steroids, WIN-compounds and cholesterol share a common binding site on muscarinic acetylcholine receptors.
Biochemical Pharmacology. Roč. 192, Oct (2021), č. článku 114699. ISSN 0006-2952. E-ISSN 1873-2968
R&D Projects: GA ČR(CZ) GA19-05318S
Grant - others:AV ČR(CZ) StrategieAV21/10
Program: StrategieAV
Institutional support: RVO:67985823 ; RVO:61388963
Keywords : neuroactive steroids * cholesterol * muscarinic receptors * allosteric modulation
OECD category: Physiology (including cytology); Physiology (including cytology) (UOCHB-X)
Impact factor: 6.100, year: 2021
Method of publishing: Open access
https://doi.org/10.1016/j.bcp.2021.114699
Permanent Link: http://hdl.handle.net/11104/0323241 - 2.0546861 - FGÚ 2022 RIV NL eng J - Journal Article
Dolejší, Eva - Szánti-Pintér, Eszter - Chetverikov, Nikolai - Nelic, Dominik - Randáková, Alena - Doležal, Vladimír - Kudová, Eva - Jakubík, Jan
Neurosteroids and steroid hormones are allosteric modulators of muscarinic receptor.
Neuropharmacology. Roč. 199, Nov 1 (2021), č. článku 108798. ISSN 0028-3908. E-ISSN 1873-7064
R&D Projects: GA ČR(CZ) GA19-05318S
Grant - others:AV ČR(CZ) StrategieAV21/10
Program: StrategieAV
Institutional support: RVO:67985823 ; RVO:61388963
Keywords : neurosteroid * steroid hormone * allosteric modulation * muscarinic receptor
OECD category: Physiology (including cytology); Physiology (including cytology) (UOCHB-X)
Impact factor: 5.273, year: 2021
Method of publishing: Open access
https://doi.org/10.1016/j.neuropharm.2021.108798
Permanent Link: http://hdl.handle.net/11104/0323238 - 3.0489273 - FGÚ 2019 RIV NL eng J - Journal Article
Randáková, Alena - Dolejší, Eva - Rudajev, Vladimír - Zimčík, Pavel - Doležal, Vladimír - El-Fakahany, E. E. - Jakubík, Jan
Role of membrane cholesterol in differential sensitivity of muscarinic receptor subtypes to persistently bound xanomeline.
Neuropharmacology. Roč. 133, May 1 (2018), s. 129-144. ISSN 0028-3908. E-ISSN 1873-7064
R&D Projects: GA ČR(CZ) GA14-05696S; GA ČR(CZ) GA17-16182S
Institutional support: RVO:67985823
Keywords : muscarinic acetylcholine receptors * membrane cholesterol * xanomeline * receptor activation * molecular dynamics
OECD category: Physiology (including cytology)
Impact factor: 4.367, year: 2018
Permanent Link: http://hdl.handle.net/11104/0283716 - 4.0466603 - FGÚ 2017 RIV GB eng J - Journal Article
Lyukmanova, E. N. - Shulepko, M. A. - Shenkarev, Z. O. - Bychkov, M. L. - Paramonov, A. S. - Chugunov, A. O. - Kulbatskii, D. S. - Arvaniti, M. - Dolejší, Eva - Schaer, T. - Arseniev, A. S. - Efremov, R. G. - Thomsen, M. S. - Doležal, Vladimír - Bertrand, D. - Dolgikh, D. A. - Kirpichnikov, M. P.
Secreted Isoform of Human Lynx1 (SLURP-2): Spatial Structure and Pharmacology of Interactions with Different Types of Acetylcholine Receptors.
Scientific Reports. Roč. 6, Aug 3 (2016), s. 30698. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA ČR(CZ) GA14-05696S
Institutional support: RVO:67985823
Keywords : ion channel * signalling * molecular modelling * protein–protein interaction networks * solution-state NMR
Subject RIV: ED - Physiology
Impact factor: 4.259, year: 2016
Permanent Link: http://hdl.handle.net/11104/0264877 - 5.0456635 - FGÚ 2016 RIV US eng J - Journal Article
Dolejší, Eva - Liraz, O. - Rudajev, Vladimír - Zimčík, Pavel - Doležal, Vladimír - Michaelson, D. M.
Apolipoprotein E4 reduces evoked hippocampal acetylcholine release in adult mice.
Journal of Neurochemistry. Roč. 136, č. 3 (2016), s. 503-509. ISSN 0022-3042. E-ISSN 1471-4159
R&D Projects: GA MŠMT(CZ) LH13269
Institutional support: RVO:67985823
Keywords : acetylcholine release * Alzheimer's disease (AD) * apolipoprotein E4 (apoE4) * hippocampus
Subject RIV: FH - Neurology
Impact factor: 4.083, year: 2016
Permanent Link: http://hdl.handle.net/11104/0257140 - 6.0454411 - FGÚ 2016 RIV NL eng J - Journal Article
Janíčková, Helena - Rudajev, Vladimír - Dolejší, Eva - Koivisto, H. - Jakubík, Jan - Tanila, H. - El-Fakahany, E. E. - Doležal, Vladimír
Lipid-Based Diets Improve Muscarinic Neurotransmission in the Hippocampus of Transgenic APPswe/PS1dE9 Mice.
Current Alzheimer Research. Roč. 12, č. 10 (2015), s. 923-931. ISSN 1567-2050. E-ISSN 1875-5828
R&D Projects: GA MŠMT(CZ) 7E10060; GA MŠMT(CZ) EE2.3.30.0025
Institutional support: RVO:67985823
Keywords : G-protein activation * hippocampus * muscarinic neurotransmission * nutrition * omega-3 fatty acids * stigmasterol
Subject RIV: FH - Neurology
Impact factor: 3.145, year: 2015
Permanent Link: http://hdl.handle.net/11104/0255091 - 7.0449347 - FGÚ 2016 RIV US eng J - Journal Article
Lyukmanova, E. N. - Shenkarev, Z. O. - Shulepko, M. A. - Paramonov, A. S. - Chugunov, A. O. - Janíčková, Helena - Dolejší, Eva - Doležal, Vladimír - Utkin, Y.N. - Tsetlin, V.I. - Arseniev, A. S. - Efremov, R. G. - Dolgikh, D. A. - Kirpichnikov, M. P.
Structural Insight into Specificity of Interactions between Nonconventional Three-finger Weak Toxin from Naja kaouthia (WTX) and Muscarinic Acetylcholine Receptors.
Journal of Biological Chemistry. Roč. 290, č. 39 (2015), s. 23616-23630. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR(CZ) GA14-05696S
Institutional support: RVO:67985823
Keywords : computer modeling * G protein-coupled receptor (GPCR) * site-directed mutagenesis
Subject RIV: ED - Physiology
Impact factor: 4.258, year: 2015
Permanent Link: http://hdl.handle.net/11104/0250926 - 8.0448654 - FGÚ 2016 RIV GB eng J - Journal Article
Randáková, Alena - Dolejší, Eva - Rudajev, Vladimír - Zimčík, Pavel - Doležal, Vladimír - El-Fakahany, E. E. - Jakubík, Jan
Classical and atypical agonists activate M1 muscarinic acetylcholine receptors through common mechanisms.
Pharmacological Research. Roč. 97, Jul 2015 (2015), s. 27-39. ISSN 1043-6618. E-ISSN 1096-1186
R&D Projects: GA ČR(CZ) GA305/09/0681; GA ČR(CZ) GBP304/12/G069; GA MŠMT(CZ) EE2.3.30.0025
Institutional support: RVO:67985823
Keywords : muscarinic acetylcholine receptors * atypical agonists * xanomeline * activation mechanism
Subject RIV: ED - Physiology
Impact factor: 4.816, year: 2015
Permanent Link: http://hdl.handle.net/11104/0250288 - 9.0428162 - FGÚ 2015 RIV CZ eng J - Journal Article
Jakubík, Jan - Šantrůčková, Eva - Randáková, Alena - Janíčková, Helena - Zimčík, Pavel - Rudajev, Vladimír - Michal, Pavel - El-Fakahany, E. E. - Doležal, Vladimír
Outline of therapeutic interventions with muscarinic receptor-mediated transmission.
Physiological Research. Roč. 63, Suppl.1 (2014), S177-S189. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA ČR(CZ) GA305/09/0681; GA ČR(CZ) GAP304/12/0259; GA MŠMT(CZ) 7E10060
Institutional support: RVO:67985823
Keywords : cholinergic transmission * muscarinic receptors * therapy * Alzheimer's disease, * schizophrenia
Subject RIV: ED - Physiology
Impact factor: 1.293, year: 2014
Permanent Link: http://hdl.handle.net/11104/0233580 - 10.0427640 - FGÚ 2015 RIV US eng J - Journal Article
Šantrůčková, Eva - Doležal, Vladimír - El-Fakahany, E. E. - Jakubík, Jan
Long-Term Activation upon Brief Exposure to Xanomleline Is Unique to M1 and M4 Subtypes of Muscarinic Acetylcholine Receptors.
PLoS ONE. Roč. 9, č. 2 (2014), e88910. ISSN 1932-6203. E-ISSN 1932-6203
R&D Projects: GA ČR(CZ) GA305/09/0681; GA ČR(CZ) GAP304/12/0259
Institutional research plan: CEZ:AV0Z50110509
Institutional support: RVO:67985823
Keywords : muscarinic receptors * functional selectivity * xanomeline
Subject RIV: ED - Physiology
Impact factor: 3.234, year: 2014
Permanent Link: http://hdl.handle.net/11104/0233140