Search results
- 1.0577921 - ÚOCHB 2024 RIV GB eng J - Journal Article
Kraina, Pavel - Česnek, Michal - Tloušťová, Eva - Mertlíková-Kaiserová, Helena - Fulton, C. J. - Davidson, E. K. - Smith, B. P. - Watts, V. J. - Janeba, Zlatko
Discovery of a potent and selective human AC2 inhibitor based on 7-deazapurine analogues of adefovir.
Bioorganic & Medicinal Chemistry. Roč. 95, November (2023), č. článku 117508. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA MŠMT LTAUSA18086
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * adefovir * 7-deazapurine * prodrugs * adenylate cyclase
OECD category: Organic chemistry
Impact factor: 3.5, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.bmc.2023.117508
Permanent Link: https://hdl.handle.net/11104/0346999 - 2.0551643 - ÚOCHB 2023 RIV DE eng J - Journal Article
Česnek, Michal - Šafránek, Michal - Dračínský, Martin - Tloušťová, Eva - Mertlíková-Kaiserová, Helena - Hayes, M. P. - Watts, V. J. - Janeba, Zlatko
Halogen-Dance-Based Synthesis of Phosphonomethoxyethyl (PME) Substituted 2-Aminothiazoles as Potent Inhibitors of Bacterial Adenylate Cyclases.
ChemMedChem. Roč. 17, č. 1 (2022), č. článku e202100568. ISSN 1860-7179. E-ISSN 1860-7187
R&D Projects: GA MŠMT LTAUSA18086
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * adenylate cyclase * Bordetella pertussis * inhibitors * prodrugs
OECD category: Organic chemistry
Impact factor: 3.4, year: 2022
Method of publishing: Limited access
https://doi.org/10.1002/cmdc.202100568
Permanent Link: http://hdl.handle.net/11104/0326883 - 3.0543267 - ÚOCHB 2022 RIV FR eng J - Journal Article
Břehová, Petra - Chaloupecká, Ema - Česnek, Michal - Skácel, Jan - Dračínský, Martin - Tloušťová, Eva - Mertlíková-Kaiserová, Helena - Soto-Velasquez, M. P. - Watts, V. J. - Janeba, Zlatko
Acyclic nucleoside phosphonates with 2-aminothiazole base as inhibitors of bacterial and mammalian adenylate cyclases.
European Journal of Medicinal Chemistry. Roč. 222, Oct 15 (2021), č. článku 113581. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA MŠMT LTAUSA18086
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * adefovir * adenylate cyclase * Bacillus anthracis * Bordetella pertussis * inhibitors * prodrugs
OECD category: Organic chemistry
Impact factor: 7.088, year: 2021
Method of publishing: Limited access
https://doi.org/10.1016/j.ejmech.2021.113581
Permanent Link: http://hdl.handle.net/11104/0320504 - 4.0493604 - ÚOCHB 2019 RIV DE eng J - Journal Article
Česnek, Michal - Skácel, Jan - Jansa, Petr - Dračínský, Martin - Šmídková, Markéta - Mertlíková-Kaiserová, Helena - Soto-Velasquez, M. - Watts, V. J. - Janeba, Zlatko
Nucleobase Modified Adefovir (PMEA) Analogues as Potent and Selective Inhibitors of Adenylate Cyclases from Bordetella pertussis and Bacillus anthracis.
ChemMedChem. Roč. 13, č. 17 (2018), s. 1779-1796. ISSN 1860-7179. E-ISSN 1860-7187
R&D Projects: GA MV VG20102015046; GA ČR(CZ) GBP208/12/G016; GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : adefovir * adenylate cyclase * Bacillus anthracis * Bordetella pertussis * inhibitors
OECD category: Organic chemistry
Impact factor: 3.016, year: 2018
Permanent Link: http://hdl.handle.net/11104/0286939 - 5.0489553 - ÚOCHB 2019 RIV DE eng J - Journal Article
Frydrych, Jan - Skácel, Jan - Šmídková, Markéta - Mertlíková-Kaiserová, Helena - Dračínský, Martin - Gnanasekaran, Ramachandran - Lepšík, Martin - Soto-Velasquez, M. - Watts, V. J. - Janeba, Zlatko
Synthesis of alpha-Branched Acyclic Nucleoside Phosphonates as Potential Inhibitors of Bacterial Adenylate Cyclases.
ChemMedChem. Roč. 13, č. 2 (2018), s. 199-206. ISSN 1860-7179. E-ISSN 1860-7187
R&D Projects: GA MV VG20102015046; GA ČR(CZ) GBP208/12/G016; GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * adenylate cyclase toxin * bisamidates * Bordetella pertussis * prodrugs
OECD category: Organic chemistry
Impact factor: 3.016, year: 2018
Permanent Link: http://hdl.handle.net/11104/0283953 - 6.0467409 - ÚOCHB 2017 RIV DE eng J - Journal Article
Břehová, Petra - Šmídková, Markéta - Skácel, Jan - Dračínský, Martin - Mertlíková-Kaiserová, Helena - Velasquez, M. P. S. - Watts, V. J. - Janeba, Zlatko
Design and Synthesis of Fluorescent Acyclic Nucleoside Phosphonates as Potent Inhibitors of Bacterial Adenylate Cyclases.
ChemMedChem. Roč. 11, č. 22 (2016), s. 2534-2546. ISSN 1860-7179. E-ISSN 1860-7187
R&D Projects: GA MV VG20102015046; GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : adenylate cyclase toxin * acyclic nucleoside phosphonates * anthranilic acid
Subject RIV: CC - Organic Chemistry
Impact factor: 3.225, year: 2016
Permanent Link: http://hdl.handle.net/11104/0265511 - 7.0446744 - ÚOCHB 2016 RIV DE eng J - Journal Article
Česnek, Michal - Jansa, Petr - Šmídková, Markéta - Mertlíková-Kaiserová, Helena - Dračínský, Martin - Brust, T. F. - Pávek, P. - Trejtnar, F. - Watts, V. J. - Janeba, Zlatko
Bisamidate Prodrugs of 2-Substituted 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA, adefovir) as Selective Inhibitors of Adenylate Cyclase Toxin from Bordetella pertussis.
ChemMedChem. Roč. 10, č. 8 (2015), s. 1351-1364. ISSN 1860-7179. E-ISSN 1860-7187
R&D Projects: GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : adenylate cyclase toxin * bisamidates * Bordetella pertussis * nucleosides * phosphonates
Subject RIV: CC - Organic Chemistry
Impact factor: 2.980, year: 2015
Permanent Link: http://hdl.handle.net/11104/0248752