Search results
- 1.0542938 - ÚOCHB 2022 RIV GB eng J - Journal Article
Tretyachenko, V. - Voráček, V. - Souček, Radko - Fujishima, K. - Hlouchová, Klára
CoLiDe: Combinatorial Library Design tool for probing protein sequence space.
Bioinformatics. Roč. 37, č. 4 (2021), s. 482-489. ISSN 1367-4803. E-ISSN 1460-2059
Institutional support: RVO:61388963
Keywords : algorithms * amino acid sequence * gene library
OECD category: Biochemistry and molecular biology
Impact factor: 6.931, year: 2021
Method of publishing: Open access
https://doi.org/10.1093/bioinformatics/btaa804
Permanent Link: http://hdl.handle.net/11104/0320262 - 2.0535965 - ÚOCHB 2021 RIV GB eng J - Journal Article
Hamissa, Mohamed Farouk - Niederhafner, Petr - Šafařík, Martin - Telus, M. - Kolářová, Lenka - Koutná, Leah - Šestáková, H. - Souček, Radko - Šebestík, Jaroslav
Total synthesis of inubosin B.
Tetrahedron Letters. Roč. 61, č. 52 (2020), č. článku 152641. ISSN 0040-4039. E-ISSN 1873-3581
R&D Projects: GA ČR(CZ) GA17-00121S; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : neuroregeneration * neurodegeneration * acridine * alkaloid * total synthesis
OECD category: Biophysics
Impact factor: 2.415, year: 2020
Method of publishing: Limited access
https://doi.org/10.1016/j.tetlet.2020.152641
Permanent Link: http://hdl.handle.net/11104/0313970 - 3.0501437 - ÚOCHB 2020 RIV US eng J - Journal Article
Matoušová, Marika - Souček, Radko - Tloušťová, Eva - Slavíková, Barbora - Chodounská, Hana - Mertlíková-Kaiserová, Helena - Kudová, Eva
Pregn-5-en-3beta-ol and androst-5-en-3beta-ol dicarboxylic acid esters as potential therapeutics for NMDA hypofunction: In vitro safety assessment and plasma stability.
Steroids. Roč. 147, Jul (2019), s. 4-9. ISSN 0039-128X. E-ISSN 1878-5867
R&D Projects: GA ČR(CZ) GA17-02300S; GA MZd(CZ) NV15-29370A; GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : neurosteroid * NMDA receptor hypofunction * hepatotoxicity * mitotoxicity * Caco-2 permeability * plasma stability
OECD category: Neurosciences (including psychophysiology
Impact factor: 1.948, year: 2019
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/abs/pii/S0039128X18301752?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0296235 - 4.0498559 - ÚOCHB 2019 RIV CH eng J - Journal Article
Adla, Santosh Kumar - Slavíková, Barbora - Chodounská, Hana - Vyklický, Vojtěch - Ladislav, Marek - Hubálková, Pavla - Krausová, Barbora - Smejkalová, Tereza - Nekardová, Michaela - Šmídková, Markéta - Monincová, Lenka - Souček, Radko - Vyklický ml., Ladislav - Kudová, Eva
Strong Inhibitory Effect, Low Cytotoxicity and High Plasma Stability of Steroidal Inhibitors of N-Methyl-D-Aspartate Receptors With C-3 Amide Structural Motif.
Frontiers in Pharmacology. Roč. 9, Nov 12 (2018), č. článku 1299. ISSN 1663-9812. E-ISSN 1663-9812
R&D Projects: GA TA ČR(CZ) TE01020028; GA ČR(CZ) GBP208/12/G016; GA ČR(CZ) GA17-02300S; GA ČR(CZ) GJ16-03913Y; GA MZd(CZ) NV15-29370A; GA MŠMT LO1302; GA MŠMT(CZ) ED1.1.00/02.0109
Grant - others:AV ČR(CZ) MSM200111601
Program: Program na podporu mezinárodní spolupráce začínajících výzkumných pracovníků
Institutional support: RVO:61388963 ; RVO:67985823
Keywords : neurosteroid * amide * NMDA receptor * plasma stability * structure-activity relationship
OECD category: Biochemistry and molecular biology
Impact factor: 3.845, year: 2018
https://www.frontiersin.org/articles/10.3389/fphar.2018.01299/full
Permanent Link: http://hdl.handle.net/11104/0291127 - 5.0482917 - ÚOCHB 2018 RIV GB eng J - Journal Article
Tretyachenko, Vyacheslav - Vymětal, Jiří - Bednárová, Lucie - Kopecký, V. Jr. - Hofbauerová, K. - Jindrová, Helena - Hubálek, Martin - Souček, Radko - Konvalinka, Jan - Vondrášek, Jiří - Hlouchová, Klára
Random protein sequences can form defined secondary structures and are well-tolerated in vivo.
Scientific Reports. Roč. 7, Nov 13 (2017), č. článku 15449. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA ČR(CZ) GBP208/12/G016
Institutional support: RVO:61388963
Keywords : amino acid sequence * de novo proteins * structure prediction
OECD category: Biochemistry and molecular biology
Impact factor: 4.122, year: 2017
https://www.nature.com/articles/s41598-017-15635-8
Permanent Link: http://hdl.handle.net/11104/0278308File Download Size Commentary Version Access 0482917.pdf 3 3.8 MB Publisher’s postprint open-access - 6.0444448 - ÚOCHB 2016 RIV US eng J - Journal Article
Tykvart, Jan - Bařinka, Cyril - Svoboda, Michal - Navrátil, Václav - Souček, Radko - Hubálek, Martin - Hradilek, Martin - Šácha, Pavel - Lubkowski, J. - Konvalinka, Jan
Structural and Biochemical Characterization of a Novel Aminopeptidase from Human Intestine.
Journal of Biological Chemistry. Roč. 290, č. 18 (2015), s. 11321-11336. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR GAP304/12/0847; GA MŠMT LO1302; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:61388963 ; RVO:86652036
Keywords : glutamate carboxypeptidase II * reaction mechanism * expression
Subject RIV: CE - Biochemistry
Impact factor: 4.258, year: 2015
Permanent Link: http://hdl.handle.net/11104/0247123