Search results
- 1.0498520 - ÚOCHB 2019 RIV US eng J - Journal Article
Tokarenko, Anna - Lišková, B. - Smolen, Sabina - Táborská, N. - Tichý, Michal - Gurská, S. - Perlíková, Pavla - Frydrych, I. - Tloušťová, Eva - Znojek, P. - Mertlíková-Kaiserová, Helena - Poštová Slavětínská, Lenka - Pohl, Radek - Klepetářová, Blanka - Khalid, N. U. A. - Wenren, Y. - Laposa, R. R. - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides.
Journal of Medicinal Chemistry. Roč. 61, č. 20 (2018), s. 9347-9359. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR(CZ) GA16-00178S; GA TA ČR(CZ) TE01020028; GA MŠMT(CZ) LO1304; GA MŠMT(CZ) LM2015064
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : hepatitis C virus * adenosine kinase inhibitors * mitochondrial RNA polymerase
OECD category: Organic chemistry
Impact factor: 6.054, year: 2018
https://pubs.acs.org/doi/full/10.1021/acs.jmedchem.8b01258
Permanent Link: http://hdl.handle.net/11104/0291128File Download Size Commentary Version Access 0498520.pdf 9 1.9 MB Publisher’s postprint open-access - 2.0494693 - ÚMG 2019 RIV GB eng J - Journal Article
Jurasek, M. - Černohorská, Markéta - Řehulka, J. - Spiwok, V. - Sulimenko, Tetyana - Dráberová, Eduarda - Darmostuk, M. - Gurska, S. - Frydrych, I. - Burianova, R. - Ruml, T. - Hajduch, M. - Bartůněk, Petr - Dráber, Pavel - Dzubak, P. - Drašar, P. B. - Sedlák, David
Estradiol dimer inhibits tubulin polymerization and microtubule dynamics.
Journal of Steroid Biochemistry and Molecular Biology. Roč. 183, Říjen (2018), s. 68-79. ISSN 0960-0760
R&D Projects: GA MŠMT LO1220; GA MŠMT(CZ) LO1304; GA MŠMT LM2015063; GA ČR GA15-22194S; GA ČR GA16-25159S
Institutional support: RVO:68378050
Keywords : Steroid dimer * Steroid receptor * Luciferase reporter assay * Microtubules * Microtubule dynamics * Tubulin assembly * Molecular dynamics simulation * Antimitotic activity
OECD category: Cell biology
Impact factor: 3.785, year: 2018
Permanent Link: http://hdl.handle.net/11104/0287788 - 3.0473082 - ÚMG 2017 RIV US eng J - Journal Article
Jurášek, M. - Džubák, P. - Rimpelová, S. - Sedlák, David - Konečný, P. - Frydrych, I. - Gurska, S. - Hajdúch, M. - Bogdanová, K. - Kolář, M. - Muller, Tomáš - Kmoníčková, Eva - Ruml, T. - Harmatha, Juraj - Drašar, P. B.
Trilobolide-steroid hybrids: Synthesis, cytotoxic and antimycobacterial activity.
Steroids. Roč. 117, JAN (2017), s. 97-104. ISSN 0039-128X. E-ISSN 1878-5867
R&D Projects: GA MŠMT(CZ) LO1304; GA MŠMT LO1220; GA MŠMT LM2015063
Grant - others:GA ČR(CZ) GA14-04329S
Institutional support: RVO:68378050 ; RVO:68378041 ; RVO:61388963
Keywords : Trilobolide * Steroids * Click chemistry * Cytotoxicity * sar * Steroid receptor
OECD category: Biochemistry and molecular biology; Organic chemistry (UOCHB-X)
Impact factor: 2.523, year: 2017
Permanent Link: http://hdl.handle.net/11104/0270248 - 4.0473046 - ÚMG 2017 RIV GB eng J - Journal Article
Mistrik, M. - Veselá, E. - Fürst, T. - Hanzlíková, Hana - Frydrych, I. - Gursky, J. - Majera, D. - Bártek, Jiří
Cells and Stripes: A novel quantitative photo-manipulation technique.
Scientific Reports. Roč. 6, JAN 18 (2016), č. článku 19567. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA ČR GA13-17555S; GA MŠMT(CZ) LO1304; GA MŠMT(CZ) ED2.3.30.0004; GA MŠMT(CZ) ED2.3.30.0041
Institutional support: RVO:68378050
Keywords : double-strand breaks * dna-damage-response * fanconi anemia/brca pathway * repair * mdc1 * chromosomes * inhibition * machinery * retention * proteins
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 4.259, year: 2016
Permanent Link: http://hdl.handle.net/11104/0270214 - 5.0455809 - ÚMG 2016 RIV US eng J - Journal Article
Kaplánek, R. - Jakubek, M. - Rak, J. - Kejik, Z. - Havlík, M. - Dolenský, B. - Frydrych, I. - Hajduch, M. - Kolář, M. - Bogdanová, K. - Králová, Jarmila - Dzubak, P. - Král, V.
Caffeine-hydrazones as anticancer agents with pronounced selectivity toward T-lymphoblastic leukaemia cells.
Bioorganic Chemistry. Roč. 60, Jun (2015), s. 19-29. ISSN 0045-2068. E-ISSN 1090-2120
Grant - others:GA MŠk(CZ) EE2.3.30.0060; GA MŠk CZ.1.07/2.3.00/30.0041; GA MŠk(CZ) LO1304
Program: EE; LD
Institutional support: RVO:68378050
Keywords : Anticancer agents * Cancer treatment * Caffeine-hydrazones * Leukaemia * Selectivity
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.252, year: 2015
Permanent Link: http://hdl.handle.net/11104/0256433