Search results
- 1.0586989 - ÚOCHB 2025 RIV US eng J - Journal Article
Krejčová, Kateřina - Krafčíková, Petra - Klíma, Martin - Chalupská, Dominika - Chalupský, Karel - Žilecká, Eva - Bouřa, Evžen
Structural and functional insights in flavivirus NS5 proteins gained by the structure of Ntaya virus polymerase and methyltransferase.
Structure. (2024). ISSN 0969-2126. E-ISSN 1878-4186
R&D Projects: GA ČR(CZ) GA21-25280S; GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Impact factor: 5.7, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.str.2024.04.020
Permanent Link: https://hdl.handle.net/11104/0354315File Download Size Commentary Version Access 10.1016j.str.2024.04.020.pdf 0 6.8 MB Publisher’s postprint open-access - 2.0583190 - ÚOCHB 2025 RIV US eng J - Journal Article
Klíma, Martin - Dejmek, Milan - Duchoslav, Vojtěch - Eisenreichová, Andrea - Šála, Michal - Chalupský, Karel - Chalupská, Dominika - Novotná, Barbora - Birkuš, Gabriel - Nencka, Radim - Bouřa, Evžen
Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: Structural basis of their function.
Structure. Roč. 32, č. 4 (2024), s. 433-439. ISSN 0969-2126. E-ISSN 1878-4186
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : cyclic GMP-AMP * binding * design
Impact factor: 5.7, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.str.2024.01.008
Permanent Link: https://hdl.handle.net/11104/0351191File Download Size Commentary Version Access 10.1016j.str.2024.01.008.pdf 0 3.1 MB Publisher’s postprint open-access - 3.0579447 - ÚOCHB 2025 RIV GB eng J - Journal Article
Misehe, Mbilo - Šála, Michal - Matoušová, Marika - Hercík, Kamil - Kocek, Hugo - Chalupská, Dominika - Chaloupecká, Ema - Hájek, Miroslav - Bouřa, Evžen - Mertlíková-Kaiserová, Helena - Nencka, Radim
Design, synthesis and evaluation of novel thieno[2,3d]pyrimidine derivatives as potent and specific RIPK2 inhibitors.
Bioorganic & Medicinal Chemistry. Roč. 97, January (2024), č. článku 129567. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA MZd(CZ) NU20-05-00472; GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : kinase inhibitor * thieno [2,3d] pyrimidine derivative * receptor-interacting protein kinase 2 * RIPK2 * NOD
Impact factor: 3.5, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.bmcl.2023.129567
Permanent Link: https://hdl.handle.net/11104/0348249File Download Size Commentary Version Access 10.1016j.bmcl.2023.129567.pdf 0 1.6 MB Publisher’s postprint open-access - 4.0574898 - ÚOCHB 2024 RIV NL eng J - Journal Article
Misehe, Mbilo - Matoušová, Marika - Dvořáková, Alexandra - Hercík, Kamil - Škach, Kryštof - Chalupská, Dominika - Dejmek, Milan - Šála, Michal - Hájek, Miroslav - Bouřa, Evžen - Mertlíková-Kaiserová, Helena - Nencka, Radim
Exploring positions 6 and 7 of a quinazoline-based scaffold leads to changes in selectivity and potency towards RIPK2/3 kinases.
European Journal of Medicinal Chemistry. Roč. 260, November (2023), č. článku 115717. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA MŠMT(CZ) LX22NPO5103; GA MZd(CZ) NU20-05-00472
Institutional support: RVO:61388963
Keywords : kinase inhibitor * quinazoline derivatives * RIPK2 * NOD * inflammation * RIPK3
OECD category: Medicinal chemistry
Impact factor: 6.7, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.ejmech.2023.115717
Permanent Link: https://hdl.handle.net/11104/0344824File Download Size Commentary Version Access 10.1016j.ejmech.2023.115717.pdf 0 4.4 MB Publisher’s postprint open-access - 5.0574244 - ÚOCHB 2024 RIV US eng J - Journal Article
Štefek, Milan - Chalupská, Dominika - Chalupský, Karel - Zgarbová, Michala - Dvořáková, Alexandra - Krafčíková, Petra - Li, A. S. M. - Šála, Michal - Dejmek, Milan - Otava, Tomáš - Chaloupecká, Ema - Kozák, Jaroslav - Kozic, Ján - Vedadi, M. - Weber, Jan - Mertlíková-Kaiserová, Helena - Nencka, Radim
Rational Design of Highly Potent SARS-CoV-2 nsp14 Methyltransferase Inhibitors.
ACS Omega. Roč. 8, č. 30 (2023), s. 27410-27418. ISSN 2470-1343. E-ISSN 2470-1343
R&D Projects: GA MZd(CZ) NU20-05-00472; GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : SARS-CoV-2 * genetics * inhibitors
OECD category: Virology
Impact factor: 4.1, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acsomega.3c02815
Permanent Link: https://hdl.handle.net/11104/0344580File Download Size Commentary Version Access acsomega.3c02815 (2).pdf 0 5.1 MB Publisher’s postprint open-access - 6.0574116 - ÚEM 2024 RIV US eng J - Journal Article
Kortus, Štěpán - Řeháková, Kristýna - Klíma, Martin - Kolcheva, Marharyta - Ladislav, Marek - Langore, Emily - Baráčková, Petra - Netolický, Jakub - Misiachna, Anna - Hemelíková, Katarína - Humpolíčková, Jana - Chalupská, Dominika - Šilhán, Jan - Kaniaková, Martina - Hrčka Krausová, Barbora - Bouřa, Evžen - Zápotocký, Martin - Horák, Martin
Subunit-Dependent Surface Mobility and Localization of NMDA Receptors in Hippocampal Neurons Measured Using Nanobody Probes.
Journal of Neuroscience. Roč. 43, č. 26 (2023), s. 4755-4774. ISSN 0270-6474. E-ISSN 1529-2401
R&D Projects: GA ČR(CZ) GA20-12420S; GA MŠMT(CZ) LX22NPO5107
Research Infrastructure: Czech-BioImaging III - 90250; Czech-BioImaging II - 90129
Institutional support: RVO:68378041 ; RVO:61388963 ; RVO:67985823
Keywords : GluN subunit * excitatory synapse * glutamate receptor * lateral diffusion * live microscopy * mammalian neuron
OECD category: Neurosciences (including psychophysiology; Biochemistry and molecular biology (UOCHB-X); Biochemistry and molecular biology (FGU-C)
Impact factor: 5.3, year: 2022
Method of publishing: Open access
https://www.jneurosci.org/content/43/26/4755
Permanent Link: https://hdl.handle.net/11104/0344475File Download Size Commentary Version Access Kortus 2023.pdf 4 4.6 MB Publisher’s postprint open-access - 7.0574061 - ÚOCHB 2024 RIV NL eng J - Journal Article
Škvára, Petr - Chalupská, Dominika - Klíma, Martin - Kozic, Ján - Šilhán, Jan - Bouřa, Evžen
Structural basis for RNA-cap recognition and methylation by the mpox methyltransferase VP39.
Antiviral Research. Roč. 216, August (2023), č. článku 105663. ISSN 0166-3542. E-ISSN 1872-9096
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : messenger-RNA * virus methyltransferase
OECD category: Virology
Impact factor: 7.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.antiviral.2023.105663
Permanent Link: https://hdl.handle.net/11104/0344428File Download Size Commentary Version Access 10.1016j.antiviral.2023.105663.pdf 1 3 MB Publisher’s postprint open-access
Research data: PDB - 8.0571446 - ÚOCHB 2024 RIV US eng J - Journal Article
Šilhán, Jan - Klíma, Martin - Otava, Tomáš - Škvára, Petr - Chalupská, Dominika - Chalupský, Karel - Kozic, Ján - Nencka, Radim - Bouřa, Evžen
Discovery and structural characterization of monkeypox virus methyltransferase VP39 inhibitors reveal similarities to SARS-CoV-2 nsp14 methyltransferase.
Nature Communications. Roč. 14, April (2023), č. článku 2259. E-ISSN 2041-1723
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : messenger RNA * recognition * binding
OECD category: Virology
Impact factor: 16.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1038/s41467-023-38019-1
Permanent Link: https://hdl.handle.net/11104/0342665File Download Size Commentary Version Access 10.1038s41467-023-38019-1.pdf 0 1.9 MB Publisher’s postprint open-access - 9.0566214 - FGÚ 2024 RIV GB eng J - Journal Article
Kolcheva, Marharyta - Ladislav, M. - Netolický, J. - Kortus, Š. - Řeháková, K. - Hrčka Krausová, B. - Hemelíková, K. - Misiachna, A. - Kádková, A. - Klíma, Martin - Chalupská, Dominika - Horák, M.
The pathogenic N650K variant in the GluN1 subunit regulates the trafficking, conductance, and pharmacological properties of NMDA receptors.
Neuropharmacology. Roč. 222, 1 January (2023), č. článku 109297. ISSN 0028-3908. E-ISSN 1873-7064
R&D Projects: GA ČR(CZ) GA20-12420S; GA MŠMT(CZ) LX22NPO5107
Institutional support: RVO:67985823 ; RVO:61388963
Keywords : glutamate receptor * hippocampal neuron * neurodegeneration * ion channel * ketamine * memantine
OECD category: Neurosciences (including psychophysiology
Impact factor: 4.7, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.neuropharm.2022.109297
Permanent Link: https://hdl.handle.net/11104/0341691 - 10.0565752 - ÚOCHB 2024 RIV DE eng J - Journal Article
Magand, J. - Roy, V. - Meudal, H. - Rose, S. - Quesniaux, V. - Chalupská, Dominika - Agrofoglio, L. A.
Synthesis of Novel 3’,3’-cyclic Dinucleotide Analogues Targeting STING Protein.
Asian Journal of Organic Chemistry. Roč. 12, č. 1 (2023), č. článku e202200597. ISSN 2193-5807. E-ISSN 2193-5815
Institutional support: RVO:61388963
Keywords : CuAAC * 3’,3’-cyclic dinucleotides * macrocyclization * ring-closing metathesis * STING protein * 1,2,3-triazole
OECD category: Organic chemistry
Impact factor: 2.7, year: 2022
Method of publishing: Open access
https://doi.org/10.1002/ajoc.202200597
Permanent Link: https://hdl.handle.net/11104/0337260