Search results

  1. 1.
    0544973 - ÚMG 2022 RIV US eng J - Journal Article
    Komulainen, E. - Badman, J. - Rey, S. - Rulten, S. - Ju, L. - Fennell, K. - Kalasová, Ilona - Ilievová, Kristýna - McKinnon, P.J. - Hanzlíková, Hana - Staras, K. - Caldecott, Keith
    Parp1 hyperactivity couples DNA breaks to aberrant neuronal calcium signalling and lethal seizures.
    Embo Reports. Roč. 22, č. 5 (2021), č. článku e51851. ISSN 1469-221X. E-ISSN 1469-3178
    Institutional support: RVO:68378050
    Keywords : DNA strand break * neurodegeneration * poly(ADP‐ * ribose) polymerase * seizures * xrcc1
    OECD category: Biochemistry and molecular biology
    Impact factor: 9.421, year: 2021
    Method of publishing: Open access
    https://www.embopress.org/doi/full/10.15252/embr.202051851
    Permanent Link: http://hdl.handle.net/11104/0321763
     
     
  2. 2.
    0544972 - ÚMG 2022 RIV US eng J - Journal Article
    Demin, A.A. - Hirota, K. - Tsuda, M. - Adamowicz, M. - Hailstone, R. - Brazina, J. - Gittens, W. - Kalasová, Ilona - Shao, Z. - Zha, S. - Sasanuma, H. - Hanzlíková, Hana - Takeda, S. - Caldecott, Keith
    XRCC1 prevents toxic PARP1 trapping during DNA base excision repair.
    Molecular Cell. Roč. 81, č. 14 (2021), s. 3018-3030. ISSN 1097-2765. E-ISSN 1097-4164
    Institutional support: RVO:68378050
    Keywords : strand-break repair * polymerase-beta * poly(adp-ribose) polymerase * polynucleotide kinase * ligase iii * molecular-cloning * adp-ribosylation * protein xrcc1 * brct domain * damage
    OECD category: Biochemistry and molecular biology
    Impact factor: 19.328, year: 2021
    Method of publishing: Open access
    https://www.cell.com/molecular-cell/fulltext/S1097-2765(21)00366-X?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS109727652100366X%3Fshowall%3Dtrue
    Permanent Link: http://hdl.handle.net/11104/0321762
     
     
  3. 3.
    0540318 - ÚMG 2021 RIV GB eng J - Journal Article
    Kalasová, Ilona - Hailstone, R. - Bublitz, J. - Bogantes, J. - Hofmann, W. - Leal, A. - Hanzlíková, Hana - Caldecott, Keith
    Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair.
    Nucleic Acids Research. Roč. 48, č. 12 (2020), s. 6672-6684. ISSN 0305-1048. E-ISSN 1362-4962
    R&D Projects: GA MŠMT(CZ) LM2015062; GA MŠMT(CZ) EF16_013/0001775; GA MŠMT LO1419
    Institutional support: RVO:68378050
    Keywords : PNKP * DNA single-strand break repair * neurologic disease PNKP
    OECD category: Cell biology
    Impact factor: 16.971, year: 2020
    Method of publishing: Open access
    https://academic.oup.com/nar/article/48/12/6672/5854143
    Permanent Link: http://hdl.handle.net/11104/0317958
     
     
  4. 4.
    0531852 - ÚMG 2021 RIV CH eng J - Journal Article
    Fáberová, Veronika - Kalasová, Ilona - Krausová, Alžběta - Hozák, Pavel
    Super-Resolution Localisation of Nuclear PI(4)P and Identification of Its Interacting Proteome.
    Cells. Roč. 9, č. 5 (2020), č. článku 1191. E-ISSN 2073-4409
    R&D Projects: GA ČR GA19-05608S; GA ČR(CZ) GA18-19714S; GA MŠMT(CZ) EF16_013/0001775; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT LTC19048; GA MŠMT(CZ) LM2018129; GA MŠMT LO1419
    Institutional support: RVO:68378050
    Keywords : nucleus * phosphoinositides * pi(4)p
    OECD category: Cell biology
    Impact factor: 6.600, year: 2020
    Method of publishing: Open access
    https://www.mdpi.com/2073-4409/9/5/1191
    Permanent Link: http://hdl.handle.net/11104/0315790
     
     
  5. 5.
    0531327 - ÚMG 2021 RIV GB eng J - Journal Article
    Hanzlíková, Hana - Prokhorova, E. - Krejčíková, Kateřina - Cihlářová, Zuzana - Kalasová, Ilona - Kubovčiak, Jan - Šáchová, Jana - Hailstone, R. - Brazina, J. - Ghosh, S. - Cirak, S. - Gleeson, J. G. - Ahel, I. - Caldecott, Keith
    Pathogenic ARH3 mutations result in ADP-ribose chromatin scars during DNA strand break repair.
    Nature Communications. Roč. 11, č. 1 (2020), č. článku 3391. E-ISSN 2041-1723
    R&D Projects: GA MŠMT(CZ) LM2015062; GA MŠMT(CZ) EF16_013/0001775; GA MŠMT LO1419; GA TA ČR TE02000058
    Institutional support: RVO:68378050
    Keywords : poly(adp-ribose) glycohydrolase * xrcc1 * binding * identification * ribosylation * degradation * specificity * serine * ataxia * roles
    OECD category: Cell biology
    Impact factor: 14.919, year: 2020
    Method of publishing: Open access
    https://www.nature.com/articles/s41467-020-17069-9
    Permanent Link: http://hdl.handle.net/11104/0310004
     
     
  6. 6.
    0508188 - ÚMG 2020 RIV US eng J - Journal Article
    Kalasová, Ilona - Hanzlíková, Hana - Gupta, N. - Li, Y. - Altmueller, J. - Reynolds, J. - Stewart, G.S. - Wollnik, B. - Yigit, G. - Caldecott, Keith
    Novel PNKP mutations causing defective DNA strand break repair and PARP1 hyperactivity in MCSZ.
    Neurology-Genetics. Roč. 5, č. 2 (2019), č. článku e320. ISSN 2376-7839. E-ISSN 2376-7839
    Institutional support: RVO:68378050
    Keywords : polynucleotide kinase * ataxia * seizures
    OECD category: Cell biology
    Impact factor: 3.509, year: 2019
    Method of publishing: Open access
    https://ng.neurology.org/content/5/2/e320
    Permanent Link: http://hdl.handle.net/11104/0305946
    FileDownloadSizeCommentaryVersionAccess
    Neurology_Genetics_I_Kalasova_2019.pdf5551.7 KBAuthor’s postprintrequire
     
     
  7. 7.
    0495899 - ÚMG 2019 RIV US eng J - Journal Article
    Hanzlíková, Hana - Kalasová, Ilona - Demin, A.A. - Pennicott, L.E. - Cihlářová, Zuzana - Caldecott, Keith
    The Importance of Poly(ADP-Ribose) Polymerase as a Sensor of Unligated Okazaki Fragments during DNA Replication.
    Molecular Cell. Roč. 71, č. 2 (2018), s. 319-331. ISSN 1097-2765. E-ISSN 1097-4164
    R&D Projects: GA MŠMT(CZ) LM2015062; GA MŠMT LO1419
    Institutional support: RVO:68378050
    Keywords : base-excision-repair * double-strand breaks * hydroxyurea-induced accumulation * immunodeficient patient 46br * poly-adp-ribose * mouse l-cells * ligase-iii * damaged dna * sv40 dna * in-vitro
    OECD category: Biochemistry and molecular biology
    Impact factor: 14.548, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0288783
    FileDownloadSizeCommentaryVersionAccess
    Molecular_Cell_H_Hanzlikova_2018.pdf34.8 MBAuthor’s postprintrequire
     
     
  8. 8.
    0494648 - ÚMG 2019 RIV GB eng J - Journal Article
    Sobol, Margaryta - Krausová, Alžběta - Yildirim, Sukriye - Kalasová, Ilona - Fáberová, Veronika - Vrkoslav, Vladimír - Philimonenko, Vlada - Marášek, Pavel - Pastorek, Lukáš - Čapek, Martin - Lubovská, Zuzana - Uličná, Lívia - Tsuji, T. - Lísa, M. - Cvačka, Josef - Fujimoto, T. - Hozák, Pavel
    Nuclear phosphatidylinositol 4,5-bisphosphate islets contribute to efficient RNA polymerase II-dependent transcription.
    Journal of Cell Science. Roč. 131, č. 8 (2018), č. článku jcs211094. ISSN 0021-9533. E-ISSN 1477-9137
    R&D Projects: GA ČR GAP305/11/2232; GA ČR(CZ) GA16-03346S; GA ČR GA15-08738S; GA TA ČR(CZ) TE01020118; GA MŠMT(CZ) EF16_013/0001775; GA MŠMT(CZ) ED1.1.00/02.0109
    Institutional support: RVO:68378050 ; RVO:61388963
    Keywords : Nucleus * PtdIns(4,5)P-2 * DNA transcription * Chromatin * RNA polymerase II * Phosphoinositides
    OECD category: Cell biology; Analytical chemistry (UOCHB-X)
    Impact factor: 4.517, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0287754
    FileDownloadSizeCommentaryVersionAccess
    Journal_of_Cell_Science_M_Sobol_2018.pdf38.9 MBPublisher’s postprintrequire
     
     
  9. 9.
    0487322 - ÚMG 2018 RIV NL eng J - Journal Article
    Uličná, Lívia - Kalendová, Alžběta - Kalasová, Ilona - Vacík, Tomáš - Hozák, Pavel
    PIP2 epigenetically represses rRNA genes transcription interacting with PHF8.
    Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids. Roč. 1863, č. 3 (2018), s. 266-275. ISSN 1388-1981. E-ISSN 1879-2618
    R&D Projects: GA ČR GA15-08738S; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT(CZ) LM2015062
    Institutional support: RVO:68378050
    Keywords : PIP2 * PHF8 * rDNA transcription * H3K9me2 * Nucleus
    OECD category: Biochemistry and molecular biology
    Impact factor: 4.402, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0281970
    FileDownloadSizeCommentaryVersionAccess
    BBA_Molecular_and_Cell_Biology_of_Lipids_L_Ulicna_2019.pdf2118.3 KBAuthor’s postprintrequire
     
     
  10. 10.
    0472618 - ÚMG 2017 RIV DE eng J - Journal Article
    Kalasová, Ilona - Fáberová, Veronika - Kalendová, Alžběta - Uličná, Lívia - Yildirim, Sukriye - Venit, Tomáš - Hozák, Pavel
    Tools for visualization of phosphoinositides in the cell nucleus.
    Histochemistry and Cell Biology. Roč. 145, č. 4 (2016), s. 485-496. ISSN 0948-6143. E-ISSN 1432-119X
    R&D Projects: GA ČR GA16-03403S; GA ČR GAP305/11/2232; GA MŠMT(CZ) ED1.1.00/02.0109; GA CR GA16-03403S
    Grant - others:Human Frontier Science Program(FR) RGP0017/2013
    Institutional support: RVO:68378050
    Keywords : Nucleus * Phosphoinositides * PI(4,5)P2 * PI(4)P
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 2.553, year: 2016
    Permanent Link: http://hdl.handle.net/11104/0269875
     
     

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