Search results
- 1.0485092 - ÚOCHB 2018 CN eng A - Abstract
Hocková, Dana - Keough, D. T. - Špaček, Petr - Terán, D. - Zíková, Alena - Eng, W. S. - Janeba, Zlatko - Naesens, L. - Chavchich, M. - West, N. P. - Edstein, M. - Guddat, L. W.
Acyclic nucleoside phosphonates (ANPs): Inhibition and structural investigations of 6-oxopurine phosphoribosyltranferases as drug targets.
IDDST 2017. BIT's 15th Annual Congress of International Drug Discovery Science and Technology. Xi'an: BIT, 2017. s. 146.
[IDDST 2017. BIT’s Annual Congress of International Drug Discovery Science and Technology /15./. 09.11.2017-11.11.2017, Xi'an]
R&D Projects: GA ČR(CZ) GA16-06049S; GA MŠMT LL1205
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : enzyme inhibitors * HGPRT * purine salvage pathvay * antiparasitic * prodrugs
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0280304 - 2.0465091 - ÚOCHB 2017 AU eng A - Abstract
Eng, W. S. - Hocková, Dana - Špaček, Petr - Janeba, Zlatko - Rejman, Dominik - West, N. P. - Woods, K. - Naesens, L. - Keough, D. T. - Guddat, L. W.
6-Oxopurine phosphoribosyltransferase as a target for the treatment of human tuberculosis.
International Congress for Tropical Medicine and Malaria 2016. Brisbane: Australian Society for Parasitology, 2016. s. 863.
[ICTMM 2016. International Congress for Tropical Medicine and Malaria /19./. 18.09.2016-22.09.2016, Brisbane]
Institutional support: RVO:61388963
Keywords : HGPRT * enzyme inhibitors * acyclic nucleoside phosphonates
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0263808 - 3.0454303 - ÚOCHB 2016 CZ eng A - Abstract
Hocková, Dana - Eng, W. S. - Špaček, Petr - Janeba, Zlatko - West, N. P. - Woods, K. - Naesens, L. M. J. - Keough, D. T. - Guddat, L. W.
Acyclic nucleoside phosphonates as inhibitors of Mycobacterium tuberculosis hypoxanthine-guanine phosphoribosyltransferase: Crystal structures and antituberculosis activity.
Liblice 2015. 50th Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2015. s. 74.
[Liblice 2015. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /50./. 06.11.2015-08.11.2015, Olomouc]
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * phosphoribosyltransferase * prodrugs
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0256239 - 4.0445799 - ÚOCHB 2016 US eng A - Abstract
Hocková, Dana - Eng, W. S. - Špaček, Petr - Janeba, Zlatko - West, N. P. - Woods, K. - Naesens, L. M. J. - Keough, D. T. - Guddat, L. W.
Acyclic nucleoside phosphonates as inhibitors of mycobacterium tuberculosis hypoxanthine-guanine phosphoribosyltransferase: Crystal structures and antituberculosis activity.
Nucleosides, Nucleotides & Oligonucleotides. Gordon Research Conference 2015. Newport: Gordon Research Conference, 2015.
[Nucleosides, Nucleotides & Oligonucleotides. Gordon Research Conference 2015. 28.06.2015-03.07.2015, Newport]
Institutional support: RVO:61388963
Keywords : nucleotide analogues * enzyme inhibitors * tuberculosis
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0247852