Search results
- 1.0546460 - FGÚ 2022 RIV CH eng J - Journal Article
Randáková, Alena - Nelic, Dominik - Hochmalová, Martina - Zimčík, Pavel - Mulenga, Mutale Jane - Boulos, J. - Jakubík, Jan
Fusion with Promiscuous G alpha(16) Subunit Reveals Signaling Bias at Muscarinic Receptors.
International Journal of Molecular Sciences. Roč. 22, č. 18 (2021), č. článku 10089. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GJ19-06106Y
Institutional support: RVO:67985823
Keywords : muscarinic receptors * signaling bias * fusion proteins * non-canonical signaling
OECD category: Pharmacology and pharmacy
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1422-0067/22/18/10089
Permanent Link: http://hdl.handle.net/11104/0322964 - 2.0524902 - FGÚ 2021 RIV US eng J - Journal Article
Randáková, Alena - Nelic, Dominik - Doležal, Vladimír - El-Fakahany, E. E. - Boulos, J. - Jakubík, Jan
Agonist-Specific Conformations of the M-2 Muscarinic Acetylcholine Receptor Assessed by Molecular Dynamics.
Journal of Chemical Information and Modeling. Roč. 60, č. 4 (2020), s. 2325-2338. ISSN 1549-9596. E-ISSN 1549-960X
R&D Projects: GA ČR(CZ) GA17-16182S; GA ČR(CZ) GJ19-06106Y
Research Infrastructure: CESNET II - 90042
Institutional support: RVO:67985823
Keywords : muscarinic receptors * agonist-specific conformations * signalling bias * accelerated molecular dynamics
OECD category: Pharmacology and pharmacy
Impact factor: 4.956, year: 2020
Method of publishing: Limited access
https://doi.org/10.1021/acs.jcim.0c00041
Permanent Link: http://hdl.handle.net/11104/0309133 - 3.0524282 - FGÚ 2021 RIV GB eng J - Journal Article
Randáková, Alena - Nelic, Dominik - Ungerová, Dana - Nwokoye, P. - Su, Q. - Doležal, Vladimír - El-Fakahany, E. E. - Boulos, J. - Jakubík, Jan
Novel M-2-selective, G(i)-biased agonists of muscarinic acetylcholine receptors.
British Journal of Pharmacology. Roč. 177, č. 9 (2020), s. 2073-2089. ISSN 0007-1188. E-ISSN 1476-5381
R&D Projects: GA ČR(CZ) GA17-16182S
Research Infrastructure: CESNET II - 90042
Institutional support: RVO:67985823
Keywords : muscarinic acetylcholine receptors * functionally selective agonists * signalling bias
OECD category: Physiology (including cytology)
Impact factor: 8.740, year: 2020
Method of publishing: Limited access
https://doi.org/10.1111/bph.14970
Permanent Link: http://hdl.handle.net/11104/0308655 - 4.0490235 - FGÚ 2019 RIV GB eng J - Journal Article
Randáková, Alena - Rudajev, Vladimír - Doležal, Vladimír - Boulos, J. - Jakubík, Jan
Novel long‐acting antagonists of muscarinic ACh receptors.
British Journal of Pharmacology. Roč. 175, č. 10 (2018), s. 1731-1743. ISSN 0007-1188. E-ISSN 1476-5381
R&D Projects: GA ČR(CZ) GA17-16182S
Institutional support: RVO:67985823
Keywords : muscarinic acetylcholine receptors * long-acting antagonists * tetrahydropyridinium slats
OECD category: Physiology (including cytology)
Impact factor: 6.583, year: 2018
Permanent Link: http://hdl.handle.net/11104/0284504 - 5.0420861 - FGÚ 2014 RIV US eng J - Journal Article
Boulos, J. - Jakubík, Jan - Randáková, Alena - Avila, C.
Synthesis of N-Substituted Piperidine Salts as Potential Muscarinic Ligands for Alzheimer's Applications.
Journal of Heterocyclic Chemistry. Roč. 50, č. 6 (2013), s. 1363-1367. ISSN 0022-152X. E-ISSN 1943-5193
R&D Projects: GA ČR(CZ) GA305/09/0681
Institutional support: RVO:67985823
Keywords : N-piperidine substituted salts * muscarinic receptor antagonists * selectivity
Subject RIV: ED - Physiology
Impact factor: 0.873, year: 2013
Permanent Link: http://hdl.handle.net/11104/0227397