Search results
- 1.0584811 - BTÚ 2025 RIV GB eng J - Journal Article
Malarikova, D. - Jorda, R. - Kupcová, K. - Senavova, J. - Dolníková, A. - Pokorná, E. - Kazantsev, D. - Nozickova, K. - Sovilj, Dana - Bellanger, C. - Chiron, D. - Anděra, Ladislav - Kryštof, V. - Strnad, Miroslav - Helman, K. - Klánová, M. - Trněný, M. - Havranek, O. - Klener, P.
Cyclin dependent kinase 4/6 inhibitor palbociclib synergizes with BCL2 inhibitor venetoclax in experimental models of mantle cell lymphoma without iRB1/i deletion.
Experimental Hematology & Oncology. Roč. 13, č. 1 (2024), č. článku 34. E-ISSN 2162-3619
Institutional support: RVO:86652036 ; RVO:61389030
Keywords : cdk4/6 * Cyclin-dependent kinase (CDK) inhibitors * Palbociclib * bcl2 * Venetoclax * rb1 * Mantle cell lymphoma (MCL)
OECD category: Oncology
Impact factor: 9.4, year: 2023
Method of publishing: Open access
https://ehoonline.biomedcentral.com/articles/10.1186/s40164-024-00499-2
Permanent Link: https://hdl.handle.net/11104/0353392 - 2.0579078 - ÚMG 2024 RIV US eng J - Journal Article
Průková, D. - Anděra, Ladislav - Nahácka, Zuzana - Karolová, J. - Svaton, M. - Klánová, M. - Havránek, O. - Soukup, J. - Svobodová, K. - Zemanová, Z. - Tušková, D. - Pokorná, E. - Helman, K. - Forsterova, K. - Pacheco-Blanco, M. - Vočková, P. - Berková, A. - Froňková, E. - Trněný, M. - Klener, P.
Cotargeting of BCL2 with Venetoclax and MCL1 with S63845 Is Synthetically Lethal In Vivo in Relapsed Mantle Cell Lymphoma.
Clinical Cancer Research. Roč. 25, č. 14 (2019), s. 4455-4465. ISSN 1078-0432. E-ISSN 1557-3265
Institutional support: RVO:68378050
Keywords : acute myeloid-leukemia * open-label * cancer * landscape * combination * cytarabine * resistance * apoptosis * overcome * abt-199
OECD category: Biochemistry and molecular biology
Impact factor: 10.107, year: 2019
Method of publishing: Limited access
https://aacrjournals.org/clincancerres/article/25/14/4455/81919/Cotargeting-of-BCL2-with-Venetoclax-and-MCL1-with
Permanent Link: https://hdl.handle.net/11104/0347951 - 3.0557905 - ÚMG 2023 RIV US eng J - Journal Article
Klánová, M. - Kazantsev, D. - Pokorná, E. - Zikmund, T. - Karolová, J. - Behounek, M. - Renesova, N. - Sovilj, D. - Kelemen, C. - Helman, K. - Jaksa, R. - Havránek, O. - Anděra, Ladislav - Trněný, M. - Klener, P.
Anti-apoptotic MCL1 Protein Represents Critical Survival Molecule for Most Burkitt Lymphomas and BCL2-negative Diffuse Large B-cell Lymphomas.
Molecular Cancer Therapeutics. Roč. 21, č. 1 (2022), s. 89-99. ISSN 1535-7163. E-ISSN 1538-8514
Institutional support: RVO:68378050
Keywords : gene-expression * elderly-patients * bcl-2 family * venetoclax * chemotherapy * inhibition * mutations * subgroups * abt-199 * dlbcl
OECD category: Oncology
Impact factor: 5.7, year: 2022
Method of publishing: Open access
https://aacrjournals.org/mct/article/21/1/89/675161/Anti-apoptotic-MCL1-Protein-Represents-Critical
Permanent Link: http://hdl.handle.net/11104/0331789 - 4.0554659 - BTÚ 2023 RIV US eng J - Journal Article
Klánová, M. - Kazantsev, D. - Pokorná, E. - Zikmund, T. - Karolová, J. - Behounek, M. - Renesova, N. - Sovilj, Dana - Kelemen, Cristina D. - Helman, K. - Jaksa, R. - Havranek, O. - Anděra, Ladislav - Trněný, M. - Klener, P.
Anti-apoptotic MCL1 Protein Represents Critical Survival Molecule for Most Burkitt Lymphomas and BCL2-negative Diffuse Large B-cell Lymphomas.
Molecular Cancer Therapeutics. Roč. 21, č. 1 (2022), s. 89-99. ISSN 1535-7163. E-ISSN 1538-8514
R&D Projects: GA ČR(CZ) GA19-08772S; GA MZd(CZ) NU21-03-00386
Institutional support: RVO:86652036
Keywords : gene-expression * elderly-patients * bcl-2 family * venetoclax * chemotherapy
OECD category: Oncology
Impact factor: 5.7, year: 2022
Method of publishing: Open access
https://aacrjournals.org/mct/article/21/1/89/675161/Anti-apoptotic-MCL1-Protein-Represents-Critical
Permanent Link: http://hdl.handle.net/11104/0331895 - 5.0398210 - ÚMG 2014 RIV GB eng J - Journal Article
Molinsky, J. - Klánová, M. - Koc, Michal - Beranová, Lenka - Anděra, Ladislav - Ludvíková, Z. - Bohmova, M. - Gasova, Z. - Strnad, Miroslav - Ivánek, R. - Trněný, M. - Nečas, E. - Živný, J. - Klener, P.
Roscovitine sensitizes leukemia and lymphoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis.
Leukemia & Lymphoma. Roč. 54, č. 2 (2013), s. 372-380. ISSN 1042-8194. E-ISSN 1029-2403
R&D Projects: GA MZd NS10287
Institutional research plan: CEZ:AV0Z50380511
Institutional support: RVO:68378050
Keywords : roscovitine * TRAIL * synergism * apoptosis * leukemia * lymphoma
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.605, year: 2013
Permanent Link: http://hdl.handle.net/11104/0228407File Download Size Commentary Version Access 2013_Molinsky_LEUKEMIA & LYMPHOMA_372.pdf 0 2.1 MB Other open-access - 6.0398204 - ÚMG 2014 RIV SK eng J - Journal Article
Leahomschi, S. - Molinsky, J. - Klánová, M. - Anděra, Ladislav - Peterka, Martin - Gasova, Z. - Klener, P. - Trněný, M. - Nečas, E. - Simonova, T. - Živný, J. - Klener, P.Jr.
Multi-level disruption of the extrinsic apoptotic pathway mediates resistance of leukemia cells to TNF-related apoptosis-inducing ligand (TRAIL).
Neoplasma. Roč. 60, č. 2 (2013), s. 223-231. ISSN 0028-2685. E-ISSN 1338-4317
Institutional support: RVO:68378050
Keywords : leukemia * drug-resistance * TRAIL * apoptosis * BCL2 family
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 1.642, year: 2013
Permanent Link: http://hdl.handle.net/11104/0228408 - 7.0394700 - ÚMG 2013 RIV US eng J - Journal Article
Beranová, Lenka - Pombinho, António R. - Špegárová, Jarmila - Koc, Michal - Klánová, M. - Molinsky, J. - Klener, P. - Bartůněk, Petr - Anděra, Ladislav
The plant alkaloid and anti-leukemia drug homoharringtonine sensitizes resistant human colorectal carcinoma cells to TRAIL-induced apoptosis via multiple mechanisms.
Apoptosis. Roč. 18, č. 6 (2013), s. 739-750. ISSN 1360-8185. E-ISSN 1573-675X
R&D Projects: GA ČR GAP301/10/1971; GA MŠMT LH12202; GA MŠMT(CZ) LC06077; GA MZd(CZ) NT13201; GA MŠMT LM2011022
Grant - others:UK(CZ) P24/LF1/3; GA UK(CZ) 259211/110709; UK(CZ) UNCE 204021
Institutional support: RVO:68378050
Keywords : harringtonine * apoptosis * death receptor * cFLIP * Mcl-1
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.614, year: 2013
Permanent Link: http://hdl.handle.net/11104/0222900File Download Size Commentary Version Access 0394700.pdf 3 893.7 KB Publisher’s postprint require 0394700.pdf 3 893.4 KB Publisher’s postprint require