Search results

  1. 1.
    0520196 - BFÚ 2020 RIV US eng J - Journal Article
    Svobodová, Jana - Procházková, J. - Kabátková, Markéta - Krkoška, Martin - Šmerdová, Lenka - Líbalová, Helena - Topinka, Jan - Kléma, J. - Kozubík, Alois - Machala, M. - Vondráček, Jan
    2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Disrupts Control of Cell Proliferation and Apoptosis in a Human Model of Adult Liver Progenitors.
    Toxicological Sciences. Roč. 172, č. 2 (2019), s. 368-384. ISSN 1096-6080. E-ISSN 1096-0929
    R&D Projects: GA ČR GA13-09766S; GA ČR(CZ) GA18-00145S; GA MŠMT(CZ) LM2015073; GA MŠMT(CZ) EF16_013/0001821
    Institutional support: RVO:68081707 ; RVO:68378041
    Keywords : aryl-hydrocarbon receptor * polycyclic aromatic-hydrocarbons * hippo-yap pathway * organ size
    OECD category: Toxicology; Toxicology (UEM-P)
    Impact factor: 3.703, year: 2019
    Method of publishing: Open access with time embargo
    https://academic.oup.com/toxsci/article-abstract/172/2/368/5571722?redirectedFrom=fulltext
    Permanent Link: http://hdl.handle.net/11104/0304886
     
     
  2. 2.
    0503107 - BFÚ 2019 RIV IE eng J - Journal Article
    Zapletal, Ondřej - Procházková, J. - Dubec, V. - Hofmanová, Jiřina - Kozubík, Alois - Vondráček, Jan
    Butyrate interacts with benzo [a] pyrene to alter expression and activities of xenobiotic metabolizing enzymes involved in metabolism of carcinogens within colon epithelial cell models.
    Toxicology. Roč. 412, JAN 15 2019 (2019), s. 1-11. ISSN 0300-483X
    R&D Projects: GA ČR GA13-09766S
    Institutional support: RVO:68081707
    Keywords : arylamine n-acetyltransferase * histone acetylation * messenger-rna * caco-2 cells
    OECD category: Pharmacology and pharmacy
    Impact factor: 4.099, year: 2019
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S0300483X18305729?via%3Dihub
    Permanent Link: http://hdl.handle.net/11104/0294926
     
     
  3. 3.
    0502960 - BFÚ 2019 RIV GB eng J - Journal Article
    Tylichová, Zuzana - Neca, J. - Topinka, Jan - Milcová, Alena - Hofmanová, Jiřina - Kozubík, Alois - Machala, M. - Vondráček, Jan
    n-3 Polyunsaturated fatty acids alter benzo[a]pyrene metabolism and genotoxicity in human colon epithelial cell models.
    Food and Chemical Toxicology. Roč. 124, FEB 2019 (2019), s. 374-384. ISSN 0278-6915. E-ISSN 1873-6351
    R&D Projects: GA ČR GA13-09766S; GA ČR(CZ) GA16-17085S
    Institutional support: RVO:68081707 ; RVO:68378041
    Keywords : polycyclic aromatic-hydrocarbons * gene-expression * dna-adducts * h2ax phosphorylation
    OECD category: Toxicology; Toxicology (UEM-P)
    Impact factor: 4.679, year: 2019
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S0278691518308949?via%3Dihub
    Permanent Link: http://hdl.handle.net/11104/0294801
     
     
  4. 4.
    0491108 - BFÚ 2019 RIV US eng J - Journal Article
    Tylichová, Zuzana - Slavík, J. - Cigánek, M. - Ovesná, P. - Krčmář, P. - Straková, Nicol - Machala, M. - Kozubík, Alois - Hofmanová, Jiřina - Vondráček, Jan
    Butyrate and docosahexaenoic acid interact in alterations of specific lipid classes in differentiating colon cancer cells.
    Journal of Cellular Biochemistry. Roč. 119, č. 6 (2018), s. 4664-4679. ISSN 0730-2312. E-ISSN 1097-4644
    R&D Projects: GA MZd(CZ) NV15-30585A; GA ČR GA13-09766S
    Institutional support: RVO:68081707
    Keywords : polyunsaturated fatty-acids * stearoyl-coa desaturase * gene-expression
    OECD category: Biochemistry and molecular biology
    Impact factor: 3.448, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0285183
     
     
  5. 5.
    0485728 - BFÚ 2018 RIV DE eng J - Journal Article
    Hofmanová, Jiřina - Slavík, J. - Ovesná, P. - Tylichová, Zuzana - Vondráček, Jan - Straková, Nicol - Vaculová, Alena - Cigánek, M. - Kozubík, Alois - Knopfová, L. - Šmarda, J. - Machala, M.
    Dietary fatty acids specifically modulate phospholipid pattern in colon cells with distinct differentiation capacities.
    European Journal of Nutrition. Roč. 56, č. 4 (2017), s. 1493-1508. ISSN 1436-6207. E-ISSN 1436-6215
    R&D Projects: GA ČR GA13-09766S; GA MZd(CZ) NV15-30585A
    Institutional support: RVO:68081707
    Keywords : docosahexaenoic acid * cancer-cells * epithelial-cells
    OECD category: Oncology
    Impact factor: 4.423, year: 2017
    Permanent Link: http://hdl.handle.net/11104/0280680
     
     
  6. 6.
    0476270 - BFÚ 2018 RIV DE eng J - Journal Article
    Zapletal, Ondřej - Tylichová, Zuzana - Neča, J. - Kohoutek, J. - Machala, M. - Milcová, Alena - Pokorná, M. - Topinka, Jan - Moyer, M.P. - Hofmanová, Jiřina - Kozubík, Alois - Vondráček, Jan
    Butyrate alters expression of cytochrome P450 1A1 and metabolism of benzo[a] pyrene via its histone deacetylase activity in colon epithelial cell models.
    Archives of Toxicology. Roč. 91, č. 5 (2017), s. 2135-2150. ISSN 0340-5761. E-ISSN 1432-0738
    R&D Projects: GA ČR(CZ) GA13-09766S; GA MŠMT(CZ) LM2015073
    Institutional support: RVO:68081707 ; RVO:68378041
    Keywords : aryl-hydrocarbon receptor * polycyclic aromatic-hydrocarbons * beta-catenin
    OECD category: Biochemistry and molecular biology; Genetics and heredity (medical genetics to be 3) (UEM-P)
    Impact factor: 5.728, year: 2017
    Permanent Link: http://hdl.handle.net/11104/0272812
     
     
  7. 7.
    0471936 - BFÚ 2017 RIV US eng J - Journal Article
    Tylichová, Zuzana - Straková, Nicol - Vondráček, Jan - Vaculová, Alena - Kozubík, Alois - Hofmanová, Jiřina
    Activation of autophagy and PPAR gamma protect colon cancer cells against apoptosis induced by interactive effects of butyrate and DHA in a cell type-dependent manner: The role of cell differentiation.
    Journal of Nutritional Biochemistry. Roč. 39, JAN2017 (2017), s. 145-155. ISSN 0955-2863. E-ISSN 1873-4847
    R&D Projects: GA ČR GA13-09766S
    Institutional support: RVO:68081707
    Keywords : polyunsaturated fatty-acids * histone deacetylase inhibitors * docosahexaenoic acid
    Subject RIV: BO - Biophysics
    Impact factor: 4.414, year: 2017
    Permanent Link: http://hdl.handle.net/11104/0269298
     
     
  8. 8.
    0456480 - BFÚ 2016 RIV GB eng J - Journal Article
    Kabátková, Markéta - Zapletal, Ondřej - Tylichová, Zuzana - Neca, J. - Machala, M. - Milcová, Alena - Topinka, Jan - Kozubík, Alois - Vondráček, Jan
    Inhibition of beta-catenin signalling promotes DNA damage elicited by benzo[a]pyrene in a model of human colon cancer cells via CYP1 deregulation.
    Mutagenesis. Roč. 30, č. 4 (2015), s. 565-576. ISSN 0267-8357. E-ISSN 1464-3804
    R&D Projects: GA ČR(CZ) GA13-09766S
    Institutional support: RVO:68081707 ; RVO:68378041
    Keywords : ARYL-HYDROCARBON RECEPTOR * POLYCYCLIC AROMATIC-HYDROCARBONS * COLORECTAL-CANCER
    Subject RIV: BO - Biophysics
    Impact factor: 2.297, year: 2015
    Permanent Link: http://hdl.handle.net/11104/0257038
     
     
  9. 9.
    0431573 - BFÚ 2015 RIV NL eng J - Journal Article
    Skender, Belma - Hofmanová, Jiřina - Slavík, J. - Jelínková, Iva - Machala, M. - Moyer, M.P. - Kozubík, Alois - Vaculová, Alena
    DHA-mediated enhancement of TRAIL-induced apoptosis in colon cancer cells is associated with engagement of mitochondria and specific alterations in sphingolipid metabolism.
    Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids. Roč. 1841, č. 9 (2014), s. 1308-1317. ISSN 1388-1981. E-ISSN 1879-2618
    R&D Projects: GA ČR(CZ) GAP301/11/1730; GA ČR(CZ) GA13-09766S
    Institutional support: RVO:68081707
    Keywords : Docosahexaenoic acid * TRAIL * Apoptosis
    Subject RIV: BO - Biophysics
    Impact factor: 5.162, year: 2014
    Permanent Link: http://hdl.handle.net/11104/0236221
     
     


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