Search results
- 1.0435229 - ÚOCHB 2015 RIV US eng J - Journal Article
Žáková, Lenka - Kletvíková, Emília - Lepšík, Martin - Collinsová, Michaela - Watson, C. J. - Turkenburg, J. P. - Jiráček, Jiří - Brzozowski, A. M.
Human insulin analogues modified at the B26 site reveal a hormone conformation that is undetected in the receptor complex.
Acta Crystallographica Section D-Biological Crystallography. Roč. 70, č. 10 (2014), s. 2765-2774. ISSN 0907-4449
R&D Projects: GA ČR GPP207/11/P430; GA ČR GBP208/12/G016
Institutional support: RVO:61388963
Keywords : insulin * insulin receptor * complex * active form * analog * structure
Subject RIV: CE - Biochemistry
Impact factor: 7.232, year: 2013
Permanent Link: http://hdl.handle.net/11104/0239539 - 2.0429734 - ÚOCHB 2015 RIV CZ cze J - Journal Article
Žáková, Lenka - Jiráček, Jiří
Pokroky ve studiu interakce inzulinu s jeho receptorem.
[Advances in Studies of Insulin Interaction with Its Receptor.]
Chemické listy. Roč. 108, č. 4 (2014), s. 368-374. ISSN 0009-2770. E-ISSN 1213-7103
R&D Projects: GA ČR GPP207/11/P430
Institutional support: RVO:61388963
Keywords : insulin * insulin receptor * crystal structure * NMR structure * complex * diabetes
Subject RIV: CE - Biochemistry
Impact factor: 0.272, year: 2014
Permanent Link: http://hdl.handle.net/11104/0234804 - 3.0429661 - ÚOCHB 2015 RIV US eng J - Journal Article
Kosinová, Lucie - Veverka, Václav - Novotná, P. - Collinsová, Michaela - Urbanová, M. - Moody, N. R. - Turkenburg, J. P. - Jiráček, Jiří - Brzozowski, A. M. - Žáková, Lenka
Insight into the Structural and Biological Relevance of the T/R Transition of the N-Terminus of the B-Chain in Human Insulin.
Biochemistry. Roč. 53, č. 21 (2014), s. 3392-3402. ISSN 0006-2960
R&D Projects: GA ČR GPP207/11/P430; GA ČR GAP208/11/0105; GA MŠMT(CZ) LK11205
Institutional support: RVO:61388963
Keywords : insulin * structure * N-terminus * B-chain * T/R transition
Subject RIV: CE - Biochemistry
Impact factor: 3.015, year: 2014
Permanent Link: http://hdl.handle.net/11104/0234773 - 4.0392749 - ÚOCHB 2014 RIV US eng J - Journal Article
Žáková, Lenka - Kletvíková, Emília - Veverka, Václav - Lepšík, Martin - Watson, C. J. - Turkenburg, J. P. - Jiráček, Jiří - Brzozowski, A. M.
Structural Integrity of the B24 Site in Human Insulin Is Important for Hormone Functionality.
Journal of Biological Chemistry. Roč. 288, č. 15 (2013), s. 10230-10240. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR GPP207/11/P430; GA MŠMT(CZ) LK11205
Institutional support: RVO:61388963
Keywords : insulin * insulin receptor * structure * NMR
Subject RIV: CE - Biochemistry
Impact factor: 4.600, year: 2013
Permanent Link: http://hdl.handle.net/11104/0221560 - 5.0391760 - ÚOCHB 2014 RIV GB eng J - Journal Article
Menting, J. G. - Whittaker, J. - Margetts, M. B. - Whittaker, L. J. - Kong, G. K. W. - Smith, B. J. - Watson, C. J. - Žáková, Lenka - Kletvíková, Emília - Jiráček, Jiří - Chan, S. J. - Steiner, D. F. - Dodson, G. G. - Brzozowski, A. M. - Weiss, M. A. - Ward, C. W. - Lawrence, M. C.
How insulin engages its primary binding site on the insulin receptor.
Nature. Roč. 493, č. 7431 (2013), s. 241-245. ISSN 0028-0836. E-ISSN 1476-4687
R&D Projects: GA ČR GPP207/11/P430
Institutional support: RVO:61388963
Keywords : insulin * receptor * complex * crystal structure
Subject RIV: CE - Biochemistry
Impact factor: 42.351, year: 2013
Permanent Link: http://hdl.handle.net/11104/0220731