Search results
- 1.0578734 - BTÚ 2024 RIV US eng J - Journal Article
Das, Gargi - Ptáček, Jakub - Havlínová, Barbora - Nedvědová, Jana - Bařinka, Cyril - Nováková, Zora
Targeting Prostate Cancer Using Bispecific T-Cell Engagers against Prostate-Specific Membrane Antigen.
ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE. Roč. 6, č. 11 (2023), s. 1703-1714. E-ISSN 2575-9108
R&D Projects: GA MŠMT LUAUS23254; GA MŠMT LX22NPO5102; GA MŠMT(CZ) LM2023050; GA MŠMT LM2023042
Research Infrastructure: CIISB III - 90242
Institutional support: RVO:86652036
Keywords : single-chain antibody * glutamate carboxypeptidase ii * x cd3 * psma * expression * immunotherapy
OECD category: Medicinal chemistry
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acsptsci.3c00159
Permanent Link: https://hdl.handle.net/11104/0347642 - 2.0574532 - BTÚ 2024 RIV US eng J - Journal Article
Motlová, Lucia - Šnajdr, Ivan - Kutil, Zsofia - Andris, Erik - Ptáček, Jakub - Novotná, Adéla - Nováková, Zora - Havlínová, Barbora - Tueckmantel, W. - Dráberová, Helena - Majer, Pavel - Schutkowski, M. - Kozikowski, A. - Rulíšek, Lubomír - Bařinka, Cyril
Comprehensive Mechanistic View of the Hydrolysis of Oxadiazole-Based Inhibitors by Histone Deacetylase 6 (HDAC6).
ACS Chemical Biology. Roč. 18, č. 7 (2023), s. 1594-1610. ISSN 1554-8929. E-ISSN 1554-8937
R&D Projects: GA ČR(CZ) GA21-31806S; GA ČR(CZ) GA23-05940S; GA MŠMT(CZ) LUAUS23247
Research Infrastructure: CIISB III - 90242; EATRIS-CZ IV - 90253
Institutional support: RVO:86652036 ; RVO:61388963
Keywords : BASIS-SETS * COSMO * ENERGY * REFINEMENT
OECD category: Biochemistry and molecular biology
Impact factor: 4, year: 2022
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acschembio.3c00212
Permanent Link: https://hdl.handle.net/11104/0347139 - 3.0571548 - BTÚ 2024 RIV CH eng J - Journal Article
Ptáček, Jakub - Šnajdr, Ivan - Schimer, Jiří - Kutil, Zsofia - Mikesova, Jana - Baranová, Petra - Havlínová, Barbora - Tueckmantel, W. - Majer, Pavel - Kozikowski, A. - Bařinka, Cyril
Selectivity of Hydroxamate- and Difluoromethyloxadiazole-Based Inhibitors of Histone Deacetylase 6 In Vitro and in Cells.
International Journal of Molecular Sciences. Roč. 24, č. 5 (2023), č. článku 4720. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA21-31806S; GA MŠMT LX22NPO5102
Institutional support: RVO:86652036 ; RVO:61388963
Keywords : metallohydrolase * histone deacetylase * inhibitor profiling * tubulin * histone acetylation * nanoBRET
OECD category: Biochemistry and molecular biology
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1422-0067/24/5/4720
Permanent Link: https://hdl.handle.net/11104/0342903 - 4.0541410 - BTÚ 2021 RIV GB eng J - Journal Article
Ptáček, Jakub - Zhang, D. - Qiu, L. - Kruspe, S. - Motlová, Lucia - Kolenko, Petr - Nováková, Zora - Shubham, S. - Havlínová, Barbora - Baranová, Petra - Chen, S.-J. - Zou, X. - Giangrande, P. - Bařinka, Cyril
Structural basis of prostate-specific membrane antigen recognition by the A9g RNA aptamer.
Nucleic Acids Research. Roč. 48, č. 19 (2020), s. 11130-11145. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA ČR(CZ) GA18-04790S; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT(CZ) LTAUSA18196
Institutional support: RVO:86652036
Keywords : GLUTAMATE-CARBOXYPEPTIDASE-II * MONOCLONAL-ANTIBODIES * CRYSTAL-STRUCTURE
OECD category: Biochemistry and molecular biology
Impact factor: 16.971, year: 2020
Method of publishing: Open access
https://academic.oup.com/nar/article/48/19/11130/5856120
Permanent Link: http://hdl.handle.net/11104/0318975 - 5.0541383 - BTÚ 2021 RIV US eng J - Journal Article
Noonepalle, S. - Shen, S. - Ptáček, Jakub - Tavares, M. T. - Zhang, G. - Stránský, Jan - Pavlíček, Jiří - Ferreira, G. M. - Hadley, M. - Pelaez, G. - Bařinka, Cyril - Kozikowski, A. P. - Villagra, A.
Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models.
Journal of Medicinal Chemistry. Roč. 63, č. 18 (2020), s. 10246-10262. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) LM2018127; GA ČR GA15-19640S; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:86652036
Keywords : antitumor-activity * force-field * hdac6 * acetylation * gromacs * charmm * implementation * metabolism * discovery * maps
OECD category: Medicinal chemistry
Impact factor: 7.446, year: 2020
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00567
Permanent Link: http://hdl.handle.net/11104/0318945 - 6.0495871 - BTÚ 2021 RIV US eng J - Journal Article
Ptáček, Jakub - Nedvědová, Jana - Navrátil, Michal - Havlínová, Barbora - Konvalinka, Jan - Bařinka, Cyril
The calcium-binding site of human glutamate carboxypeptidase II is critical for dimerization, thermal stability, and enzymatic activity.
Protein Science. Roč. 27, č. 9 (2018), s. 1575-1584. ISSN 0961-8368. E-ISSN 1469-896X
R&D Projects: GA ČR(CZ) GBP208/12/G016; GA MŠMT(CZ) ED2.1.00/19.0390; GA MŠMT(CZ) EF16_013/0001776; GA ČR(CZ) GA18-14167S
Institutional support: RVO:86652036 ; RVO:61388963
Keywords : prostate-specific membrane antigen * NAALADase * folate hydrolase
OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (UOCHB-X)
Impact factor: 2.420, year: 2018
Method of publishing: Open access
https://onlinelibrary.wiley.com/doi/full/10.1002/pro.3460
Permanent Link: http://hdl.handle.net/11104/0288755 - 7.0469171 - BTÚ 2017 RIV US eng J - Journal Article
Nováková, Zora - Wozniak, K. - Jančařík, Andrej - Rais, R. - Wu, Y. - Pavlíček, Jiří - Ferraris, D. - Havlínová, Barbora - Ptáček, Jakub - Vávra, Jan - Hin, N. - Rojas, C. - Majer, Pavel - Slusher, B. S. - Tsukamoto, T. - Bařinka, Cyril
Unprecedented Binding Mode of Hydroxamate-Based Inhibitors of Glutamate Carboxypeptidase II: Structural Characterization and Biological Activity.
Journal of Medicinal Chemistry. Roč. 59, č. 10 (2016), s. 4539-4550. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) ED1.1.00/02.0109; GA ČR GAP301/12/1513
Institutional support: RVO:86652036 ; RVO:61388963
Keywords : LINKED ACIDIC DIPEPTIDASE * N-ACETYLASPARTYLGLUTAMATE NAAG * THIOL-BASED INHIBITORS
Subject RIV: FR - Pharmacology ; Medidal Chemistry; CC - Organic Chemistry (UOCHB-X)
Impact factor: 6.259, year: 2016
Permanent Link: http://hdl.handle.net/11104/0267014 - 8.0467186 - BTÚ 2017 RIV US eng J - Journal Article
Bařinka, Cyril - Ptáček, Jakub - Richter, A. - Nováková, Zora - Morath, V. - Skerra, A.
Selection and characterization of Anticalins targeting human prostate-specific membrane antigen (PSMA).
Protein Engineering Design and Selection. Roč. 29, č. 3 (2016), s. 105-115. ISSN 1741-0126. E-ISSN 1741-0134
R&D Projects: GA ČR GAP301/12/1513
Grant - others:GA MŠk(CZ) CZ.1.05/1.1.00/02.0109
Institutional support: RVO:86652036
Keywords : Anticalin * lipocalin * glutamate carboxypeptidase II * non-immunoglobulin scaffold
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.043, year: 2016
Permanent Link: http://hdl.handle.net/11104/0265303 - 9.0456306 - BTÚ 2016 RIV GB eng J - Journal Article
Youn, S. - Kim, K.I. - Ptáček, Jakub - Ok, K. - Nováková, Zora - Kim, Y. - Koo, J. - Bařinka, Cyril - Byun, Y.
Carborane-containing urea-based inhibitors of glutamate carboxypeptidase II: Synthesis and structural characterization.
Bioorganic and Medicinal Chemistry Letters. Roč. 25, č. 22 (2015), s. 5232-5236. ISSN 0960-894X. E-ISSN 1464-3405
R&D Projects: GA ČR GAP301/12/1513; GA MŠMT(CZ) ED1.1.00/02.0109
Grant - others:GA MŠk(CZ) CZ.1.07/2.3.00/30.0045
Institutional support: RVO:86652036
Keywords : Carborane * Glutamate carboxypeptidase II * X-ray crystal structure
Subject RIV: FR - Pharmacology ; Medidal Chemistry
Impact factor: 2.486, year: 2015
Permanent Link: http://hdl.handle.net/11104/0256890 - 10.0433586 - BTÚ 2015 RIV GB eng J - Journal Article
Pavlíček, Jiří - Ptáček, Jakub - Černý, Jiří - Byun, Y. - Škultétyová, Ĺubica - Pomper, M.G. - Lubkowski, J. - Bařinka, Cyril
Structural characterization of P1 '-diversified urea-based inhibitors of glutamate carboxypeptidase II.
Bioorganic and Medicinal Chemistry Letters. Roč. 24, č. 10 (2014), s. 2340-2345. ISSN 0960-894X. E-ISSN 1464-3405
R&D Projects: GA MŠMT(CZ) ED1.1.00/02.0109
Grant - others:EMBO(DE) 1978
Institutional support: RVO:86652036
Keywords : GCPII * Prostate-specific membrane antigen * PSMA
Subject RIV: FR - Pharmacology ; Medidal Chemistry
Impact factor: 2.420, year: 2014
Permanent Link: http://hdl.handle.net/11104/0238115File Download Size Commentary Version Access Pavlicek_BioorgMedChemLett_24_2340_14.pdf 6 1.3 MB Publisher’s postprint require