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- 1.0573306 - ÚFCH JH 2024 RIV NL eng J - Journal Article
Ventura, A. E. - Pokorná, Šárka - Huhn, N. - Santos, T. C. B. - Prieto, M. - Futerman, A. H. - Silva, L. C.
Cell lipid droplet heterogeneity and altered biophysical properties induced by cell stress and metabolic imbalance.
Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids. Roč. 1868, č. 9 (2023), č. článku 159347. ISSN 1388-1981. E-ISSN 1879-2618
Institutional support: RVO:61388955
Keywords : Cancer * Fluorescence microscopy * Laurdan generalized polarization * Lipid droplet diversity * Lipid droplet hydrophobicity * Live cell imaging
OECD category: Physical chemistry
Impact factor: 4.8, year: 2022
Method of publishing: Open access
Permanent Link: https://hdl.handle.net/11104/0343772File Download Size Commentary Version Access 0573306.pdf 0 2.8 MB open access Publisher’s postprint open-access - 2.0570872 - ÚFCH JH 2024 RIV GB eng J - Journal Article
Pokorná, Šárka - Khersonsky, O. - Lipsh-Sokolik, R. - Goldenzweig, A. - Nielsen, R. - Ashani, Y. - Peleg, Y. - Unger, T. - Albeck, S. - Dym, O. - Tirosh, A. - Tarayra, R. - Hocquemiller, M. - Laufer, R. - Ben-Dor, S. - Silman, I. - Sussman, J. L. - Fleishman, S. J. - Futerman, A. H.
Design of a stable human acid-β-glucosidase: towards improved Gaucher disease therapy and mutation classification.
FEBS Journal. Roč. 290, č. 13 (2023), s. 3383-3399. ISSN 1742-464X. E-ISSN 1742-4658
Institutional support: RVO:61388955
Keywords : Gaucher disease * gene therapy * in silico mutation classification * pross * Rosetta * SNPs
OECD category: Physical chemistry
Impact factor: 5.4, year: 2022
Method of publishing: Open access
Permanent Link: https://hdl.handle.net/11104/0342198File Download Size Commentary Version Access 0570872.pdf 0 1.6 MB open access Publisher’s postprint open-access - 3.0554821 - ÚFCH JH 2023 RIV CH eng J - Journal Article
Pokorná, Šárka - Ventura, A. E. - Santos, T. C. B. - Hof, Martin - Prieto, M. - Futerman, A. H. - Silva, L. C.
Laurdan in live cell imaging: Effect of acquisition settings, cell culture conditions and data analysis on generalized polarization measurements.
Journal of Photochemistry and Photobiology. B - Biology Section. Roč. 228, MAR 2022 (2022), č. článku 112404. ISSN 1011-1344. E-ISSN 1873-2682
R&D Projects: GA ČR(CZ) GX19-26854X
Institutional support: RVO:61388955
Keywords : Cell membrane biophysical properties * Fluorescence microscopy * Laurdan GP * Live cell imaging * Membrane fluidity * Microspectroscopy
OECD category: Physical chemistry
Impact factor: 5.4, year: 2022
Method of publishing: Limited access
Permanent Link: http://hdl.handle.net/11104/0329462File Download Size Commentary Version Access 0554821.pdf 1 8 MB Publisher’s postprint require - 4.0542461 - ÚFCH JH 2022 RIV NL eng J - Journal Article
Carreira, A. C. - Pokorná, Šárka - Ventura, A. E. - Walker, M. W. - Futerman, A. H. - Lloyd-Evans, E. - de Almeida, R. F.M. - Silva, L. C.
Biophysical impact of sphingosine and other abnormal lipid accumulation in Niemann-Pick disease type C cell models.
Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids. Roč. 1866, č. 8 (2021), č. článku 158944. ISSN 1388-1981. E-ISSN 1879-2618
Institutional support: RVO:61388955
Keywords : Cholesterol * Lipid domains * Lysosomal storage diseases * Membrane fluidity * Niemann-Pick disease type C * Sphingosine
OECD category: Physical chemistry
Impact factor: 5.228, year: 2021
Method of publishing: Limited access
Permanent Link: http://hdl.handle.net/11104/0319870File Download Size Commentary Version Access 0542461.pdf 2 5.1 MB Publisher’s postprint require - 5.0523363 - ÚFCH JH 2021 RIV GB eng J - Journal Article
Tuerková, A. - Kabelka, I. - Králová, T. - Sukeník, L. - Pokorná, Šárka - Hof, Martin - Vácha, R.
Effect of helical kink in antimicrobial peptides on membrane pore formation.
eLife. Roč. 9, FEB 2020 (2020), č. článku 47946. ISSN 2050-084X. E-ISSN 2050-084X
R&D Projects: GA ČR(CZ) GX19-26854X
Grant - others:Ga MŠk(CZ) LM2015070; GA MŠk(CZ) LM2015042; GA MŠk(CZ) LM2015085
Institutional support: RVO:61388955
Keywords : antimicrobial peptides * membranes * fluorescence
OECD category: Physical chemistry
Impact factor: 8.146, year: 2020
Method of publishing: Open access
Permanent Link: http://hdl.handle.net/11104/0307723File Download Size Commentary Version Access 0523363.pdf 6 9.6 MB open access Publisher’s postprint open-access - 6.0522602 - ÚFCH JH 2021 RIV GB eng J - Journal Article
Lopez Mora, N. - Boyle, A. L. - van Kolck, B. J. - Rossen, A. - Pokorná, Šárka - Koukalová, Alena - Šachl, Radek - Hof, Martin - Kros, A.
Controlled Peptide-Mediated Vesicle Fusion Assessed by Simultaneous Dual-Colour Time-Lapsed Fluorescence Microscopy.
Scientific Reports. Roč. 10, č. 1 (2020), č. článku 3087. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA ČR(CZ) GA18-04871S; GA ČR(CZ) GX19-26854X
Institutional support: RVO:61388955
Keywords : liposomes * membrane fusion * peptides
OECD category: Physical chemistry
Impact factor: 4.380, year: 2020
Method of publishing: Open access
Permanent Link: http://hdl.handle.net/11104/0307069File Download Size Commentary Version Access 0522602.pdf 4 2.2 MB open access Publisher’s postprint open-access - 7.0517192 - ÚFCH JH 2020 RIV US eng J - Journal Article
Melcrová, Adéla - Pokorná, Šárka - Vošahlíková, Miroslava - Sýkora, Jan - Svoboda, Petr - Hof, Martin - Cwiklik, Lukasz - Jurkiewicz, Piotr
Concurrent Compression of Phospholipid Membranes by Calcium and Cholesterol.
Langmuir. Roč. 35, č. 35 (2019), s. 11358-11368. ISSN 0743-7463
R&D Projects: GA ČR(CZ) GA17-05903S; GA ČR(CZ) GA18-26751S
Grant - others:GA MŠk(CZ) LM2015042
Institutional support: RVO:61388955 ; RVO:67985823
Keywords : hek293 cells * bilayer-membranes * divalent-cations * lipid-bilayers * fusion protein * binding * hydration * fluorescence * dynamics * sodium
OECD category: Physical chemistry; Biochemical research methods (FGU-C)
Impact factor: 3.557, year: 2019
Method of publishing: Limited access
Permanent Link: http://hdl.handle.net/11104/0302482File Download Size Commentary Version Access 0517192.pdf 1 2.9 MB Publisher’s postprint require - 8.0503732 - ÚFCH JH 2020 RIV GB eng J - Journal Article
Filipe, H. A. L. - Pokorná, Šárka - Hof, Martin - Amaro, Mariana - Loura, L. M. S.
Orientation of nitro-group governs the fluorescence lifetime of nitrobenzoxadiazole (NBD)-labeled lipids in lipid bilayers.
Physical Chemistry Chemical Physics. Roč. 21, č. 4 (2019), s. 1682-1688. ISSN 1463-9076. E-ISSN 1463-9084
R&D Projects: GA ČR GA17-03160S
Institutional support: RVO:61388955
Keywords : time-resolved fluorescence * coarse-grained model * molecular-dynamics * force-field * n-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)-labeled lipids * cell-membranes
OECD category: Physical chemistry
Impact factor: 3.430, year: 2019
Method of publishing: Limited access
Permanent Link: http://hdl.handle.net/11104/0295523File Download Size Commentary Version Access 0503732.pdf 16 4 MB Publisher’s postprint require - 9.0495130 - ÚFCH JH 2019 RIV GB eng J - Journal Article
Koukalová, Alena - Pokorná, Šárka - Boyle, A. L. - Lopez Mora, N. - Kros, A. - Hof, Martin - Šachl, Radek
Distinct roles of SNARE-mimicking lipopeptides during initial steps of membrane fusion.
Nanoscale. Roč. 10, č. 40 (2018), s. 19064-19073. ISSN 2040-3364. E-ISSN 2040-3372
R&D Projects: GA ČR(CZ) GA18-04871S; GA ČR(CZ) GA17-05903S
Institutional support: RVO:61388955
Keywords : COILED-COIL PEPTIDES * SELECTIVE VESICLE FUSION * MEDIATED LIPOSOME FUSION
OECD category: Physical chemistry
Impact factor: 6.970, year: 2018
Permanent Link: http://hdl.handle.net/11104/0288145File Download Size Commentary Version Access 0495130.pdf 7 1.7 MB Publisher’s postprint require - 10.0485588 - ÚFCH JH 2019 RIV US eng J - Journal Article
Braun, S. - Pokorná, Šárka - Šachl, Radek - Hof, Martin - Heerklotz, H. - Hoernke, M.
Biomembrane Permeabilization: Statistics of Individual Leakage Events Harmonize the Interpretation of Vesicle Leakage.
ACS Nano. Roč. 12, č. 1 (2018), s. 813-819. ISSN 1936-0851. E-ISSN 1936-086X
R&D Projects: GA ČR GA17-03160S
Institutional support: RVO:61388955
Keywords : leakage * dye release * pore
OECD category: Physical chemistry
Impact factor: 13.903, year: 2018
Permanent Link: http://hdl.handle.net/11104/0280535File Download Size Commentary Version Access 0485588.pdf 4 637.3 KB Publisher’s postprint require