Search results
- 1.0377476 - ÚOCHB 2013 RIV GB eng J - Journal Article
Maarseveen van, N. M. - Andersson, Dan - Lepšík, Martin - Fun, A. - Schipper, P. J. - Jong de, D. - Boucher, Ch. A. B. - Nijhuis, M.
Modulation of HIV-1 Gag NC/p1 cleavage efficiency affects protease inhibitor resistance and viral replicative capacity.
Retrovirology. Roč. 9, č. 29 (2012), s. 1-7. E-ISSN 1742-4690
EU Projects: European Commission(XE) 37693 - HIV PI RESISTANCE
Grant - others:Dutch AIDS Fund(XE) 2006028; (NWO) VIDI(XE) 91796349
Institutional research plan: CEZ:AV0Z40550506
Keywords : HIV-1 * protease * Gag * resistance * cleavage
Subject RIV: CE - Biochemistry
Impact factor: 5.657, year: 2012
Permanent Link: http://hdl.handle.net/11104/0209622 - 2.0332864 - ÚOCHB 2010 RIV US eng J - Journal Article
Řezáčová, Pavlína - Pokorná, Jana - Brynda, Jiří - Kožíšek, Milan - Cígler, Petr - Lepšík, Martin - Fanfrlík, Jindřich - Řezáč, Jan - Grantz Šašková, Klára - Sieglová, Irena - Plešek, Jaromír - Šícha, Václav - Grüner, Bohumír - Oberwinkler, H. - Sedláček, Juraj - Kräusslich, H. G. - Hobza, Pavel - Král, V. - Konvalinka, Jan
Design of HIV protease inhibitors based on inorganic polyhedral metallacarboranes.
Journal of Medicinal Chemistry. Roč. 52, č. 22 (2009), s. 7132-7141. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA AV ČR IAAX00320901; GA MŠMT LC512; GA MŠMT LC523
EU Projects: European Commission(XE) 37693 - HIV PI RESISTANCE
Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z50520514; CEZ:AV0Z40320502
Keywords : HIV protease inhibitors * aspartic proteases * viral resistance * cobalt bis(dicarbollide) * crystal structure
Subject RIV: CC - Organic Chemistry
Impact factor: 4.802, year: 2009
Permanent Link: http://hdl.handle.net/11104/0177990 - 3.0330753 - ÚOCHB 2010 RIV US eng J - Journal Article
Grantz Šašková, Klára - Kožíšek, Milan - Řezáčová, Pavlína - Brynda, Jiří - Yashina, T. - Kagan, R. M. - Konvalinka, Jan
Molecular Characterization of Clinical Isolates of Human Immunodeficiency Virus Resistant to the Protease Inhibitor Darunavir.
Journal of Virology. Roč. 83, č. 17 (2009), s. 8810-8818. ISSN 0022-538X. E-ISSN 1098-5514
R&D Projects: GA MŠMT 1M0508
EU Projects: European Commission(XE) 37693 - HIV PI RESISTANCE
Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z50520514
Keywords : HIV-1 protease * darunavir * X-ray structural analysis * protease inhibitor * mutations
Subject RIV: CE - Biochemistry
Impact factor: 5.150, year: 2009
Permanent Link: http://hdl.handle.net/11104/0176467 - 4.0315682 - ÚOCHB 2009 RIV US eng J - Journal Article
Fanfrlík, Jindřich - Brynda, Jiří - Řezáč, Jan - Hobza, Pavel - Lepšík, Martin
Interpretation of protein/ligand crystal structure using QM/MM calculations: Case of HIV-1 protease/metallacarborane complex.
[Interpretace krystalové struktury komplexu protein-ligand pomocí výpočtů QM/MM: Studie komplexu HIV-1 proteasy a metalakarboranu.]
Journal of Physical Chemistry B. Roč. 112, č. 47 (2008), s. 15094-15102. ISSN 1520-6106. E-ISSN 1520-5207
R&D Projects: GA MŠMT LC512; GA MŠMT(CZ) LC06077; GA ČR(CZ) GD203/05/H001
EU Projects: European Commission(XE) 37693 - HIV PI RESISTANCE
Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z50520514
Keywords : X-ray * quantum mechanics * molecular mechanics * enzyme * carborane
Subject RIV: CF - Physical ; Theoretical Chemistry
Impact factor: 4.189, year: 2008
Permanent Link: http://hdl.handle.net/11104/0004888 - 5.0312670 - ÚOCHB 2009 RIV US eng J - Journal Article
Kožíšek, Milan - Cígler, Petr - Lepšík, Martin - Fanfrlík, Jindřich - Řezáčová, Pavlína - Brynda, Jiří - Pokorná, Jana - Plešek, Jaromír - Grüner, Bohumír - Grantz Šašková, Klára - Prejdová, Jana - Král, V. - Konvalinka, Jan
Inorganic polyhedral metallacarborane inhibitors of HIV protease: a new approach to overcoming antiviral resistance.
[Anorganické polyhedrální metallakarborany jako inhibitory HIV proteasy : nový přístup k překonání virové resistence.]
Journal of Medicinal Chemistry. Roč. 51, č. 15 (2008), s. 4839-4843. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT 1M0508; GA MŠMT LC512; GA MŠMT LC523; GA MZd NR8571
EU Projects: European Commission(XE) 37693 - HIV PI RESISTANCE
Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z50520514; CEZ:AV0Z40320502
Keywords : HIV protease inhibitors * aspartic proteases * viral resistance * metallacarboranes
Subject RIV: CE - Biochemistry
Impact factor: 4.898, year: 2008
Permanent Link: http://hdl.handle.net/11104/0163669