Search results
- 1.0568179 - ÚOCHB 2023 GB eng A - Abstract
Brynda, Jiří - Kugler, Michael - Nekvinda, Jan - Holub, Josef - El Anwar, Suzan - Das, V. - Šícha, Václav - Pospíšilová, Klára - Fábry, Milan - Král, Vlastimil - Pachl, Petr - Hajdúch, M. - Grüner, Bohumír - Řezáčová, Pavlína
Structure-assisted design of inhibitors of CA IX enzyme based on polyhedral boron compounds.
Acta Crystallographica Section A-Foundation and Advances. Oxford Blackwell. Roč. 77 (2021), C864-C864. ISSN 2053-2733. E-ISSN 2053-2733
Institutional support: RVO:61388963 ; RVO:61388980 ; RVO:68378050
Keywords : carborane * cobal bis(dicarbollide) * carbonic anhydrase * enzyme inhibition * SAR study
https://journals.iucr.org/a/issues/2021/a2/00/a60441/a60441.pdf
Permanent Link: https://hdl.handle.net/11104/0339514 - 2.0544944 - ÚOCHB 2022 GB eng A - Abstract
Baykov, I. - Chojnowski, G. - Pachl, Petr - Emelianova, L. - Moor, N. - Řezáčová, Pavlína - Lamzin, V. - Tikunova, N.
Structural basis of antiviral activity of a protective antibody against tick-borne encephalitis virus and structure-guided rational design of this antibody.
FEBS Open Bio. Wiley. Roč. 11, Suppl 1 (2021), s. 214. ISSN 2211-5463. E-ISSN 2211-5463.
[FEBS Congress, Molecules of Life: Towards New Horizons /45./. 03.07.2021-08.07.2021, online]
Institutional support: RVO:61388963
OECD category: Biochemistry and molecular biology
https://doi.org/10.1002/2211-5463.13205
Permanent Link: http://hdl.handle.net/11104/0321729 - 3.0521075 - ÚOCHB 2020 CA eng A - Abstract
Magdolenová, Alžbeta - Schovánková, Andrea - Pachl, Petr - Parkan, K. - Prouza, V. - Páv, Ondřej - Pohl, Radek - Hájek, Miroslav
Immunomodulatory Effects of Novel Galectin-1 Inhibitors.
CYTO 2019. 34th Congress of the International Society for Advancement of Cytometry. Vancouver: ISAC, 2019. s. 354.
[CYTO 2019. Congress of the International Society for Advancement of Cytometry /34./. 22.06.2019-26.06.2019, Vancouver]
R&D Projects: GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : flow cytometry * galectin-1 * T-cell apoptosis
OECD category: Cell biology
Permanent Link: http://hdl.handle.net/11104/0305767 - 4.0506263 - ÚOCHB 2020 CZ eng A - Abstract
Skácel, Jan - Baszczyňski, Ondřej - Mertlíková-Kaiserová, Helena - Tloušťová, Eva - Pachl, Petr - Maloy Řezáčová, Pavlína - Snášel, Jan - Pichová, Iva - Janeba, Zlatko
Development of purine nucleoside phosphorylase inhibitors as potential anticancer therapeutics.
Czech Chemical Society Symposium Series. Roč. 17, č. 1 (2019), s. 34. ISSN 2336-7202.
[Interdisciplinary Meeting of Young Researchers and Students in the Field of Chemistry, Biochemistry, Molecular Biology, and Biomaterials /19./. 20.05.2019-23.05.2019, Milovy]
R&D Projects: GA TA ČR(CZ) TN01000013
Institutional support: RVO:61388963
Keywords : PNP * anticancer therapeutics
OECD category: Organic chemistry
Permanent Link: http://hdl.handle.net/11104/0297752 - 5.0485143 - ÚOCHB 2018 US eng A - Abstract
Kožíšek, Milan - Pokorná, Jana - Pachl, Petr - Řezáčová, Pavlína - Machara, Aleš - Hejdánek, Jakub - Karlukova, Elena - Konvalinka, Jan
Kinetic, Structural and Thermodynamic Analysis of the H275Y, I223V and S247N Neuraminidase Resistant Mutants of H1N1 2009 Pandemic Influenza Virus.
30th International Conference on Antiviral Research (ICAR). Atlanta: ISAR, 2017. s. 79.
[International Conference on Antiviral Research /30./. 21.05.2017-25.05.2017, Atlanta]
Institutional support: RVO:61388963
Keywords : H1N1 * NAIs * resistance
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0280343 - 6.0480717 - ÚOCHB 2018 GB eng A - Abstract
Tichá, Anežka - Stanchev, Stancho - Vinothkumar, K. - Mikles, David C. - Pachl, Petr - Švehlová, Kateřina - Nguyen, M. - Verhelst, S. - Johnson, D. - Bachovchin, D. - Majer, Pavel - Stříšovský, Kvido
A modular and generalizable route to potent, selective and pharmacologically compliant inhibitors of rhomboid proteases.
FEBS Journal. Roč. 284, Suppl 1 (2017), s. 335. ISSN 1742-464X. E-ISSN 1742-4658.
[FEBS Congress /42./ From Molecules to Cells and Back. 10.09.2017-14.09.2017, Jerusalem]
Institutional support: RVO:61388963
Keywords : rhomboid proteases * inhibitors
Subject RIV: CE - Biochemistry
Permanent Link: http://hdl.handle.net/11104/0276423 - 7.0480709 - ÚOCHB 2018 GB eng A - Abstract
Srp, Jaroslav - Pachl, Petr - Mishra, Manasi - Horn, Martin - Mareš, Michael
A novel non-canonical binding mode for serine proteases on plant Kunitz inhibitors.
FEBS Journal. Roč. 284, Suppl 1 (2017), s. 299. ISSN 1742-464X. E-ISSN 1742-4658.
[FEBS Congress /42./ From Molecules to Cells and Back. 10.09.2017-14.09.2017, Jerusalem]
Institutional support: RVO:61388963
Keywords : Kunitz inhibitors * serine proteases
Subject RIV: CE - Biochemistry
Permanent Link: http://hdl.handle.net/11104/0276416 - 8.0443510 - ÚOCHB 2016 CZ eng A - Abstract
Srp, Jaroslav - Pachl, Petr - Řezáčová, Pavlína - Vondrášek, Jiří - Nussbaumerová, Martina - Horn, Martin - Mareš, Michael
A plant-insect interaction in 3D.
Materials Structure in Chemistry, Biology, Physics and Technology. Czech and Slovak Crystallographic Association. Roč. 22, č. 1 (2015), s. 55. ISSN 1211-5894.
[Discussions in Structural Molecular Biology. Annual Meeting of the Czech Society for Structural Biology /13./. 19.03.2015-21.03.2015, Nové Hrady]
Institutional support: RVO:61388963
Keywords : LdCD * potato cathepsin D inhibitor * crystal structure
Subject RIV: CE - Biochemistry
Permanent Link: http://hdl.handle.net/11104/0246311 - 9.0443412 - ÚOCHB 2016 CZ eng A - Abstract
Hnízda, Aleš - Škerlová, Jana - Šinalová, Martina - Pachl, Petr - Man, Petr - Novák, Petr - Fábry, Milan - Řezáčová, Pavlína - Veverka, Václav
Structural basis for hyperactivity of cN-II mutants.
Materials Structure in Chemistry, Biology, Physics and Technology. Czech and Slovak Crystallographic Association. Roč. 22, č. 1 (2015), s. 4. ISSN 1211-5894.
[Discussions in Structural Molecular Biology. Annual Meeting of the Czech Society for Structural Biology /13./. 19.03.2015-21.03.2015, Nové Hrady]
Institutional support: RVO:61388963 ; RVO:68378050 ; RVO:61388971
Keywords : cN-II mutants * enzyme hyperactivity
Subject RIV: CE - Biochemistry
Permanent Link: http://hdl.handle.net/11104/0246284 - 10.0443405 - ÚOCHB 2016 CZ eng A - Abstract
Brynda, Jiří - Pachl, Petr - Šícha, Václav - Fábry, Milan - Grüner, Bohumír - Cígler, Petr - Řezáčová, Pavlína
Carborane-based inhibitors of carbonic anhydrases.
Materials Structure in Chemistry, Biology, Physics and Technology. Czech and Slovak Crystallographic Association. Roč. 22, č. 1 (2015), s. 3. ISSN 1211-5894.
[Discussions in Structural Molecular Biology. Annual Meeting of the Czech Society for Structural Biology /13./. 19.03.2015-21.03.2015, Nové Hrady]
R&D Projects: GA ČR GA15-05677S
Institutional support: RVO:61388963 ; RVO:68378050 ; RVO:61388980
Keywords : carboranes * carbonic anhydrase
Subject RIV: CE - Biochemistry
Permanent Link: http://hdl.handle.net/11104/0246131