Search results

  1. 1.
    0584811 - BTÚ 2025 RIV GB eng J - Journal Article
    Malarikova, D. - Jorda, R. - Kupcová, K. - Senavova, J. - Dolníková, A. - Pokorná, E. - Kazantsev, D. - Nozickova, K. - Sovilj, Dana - Bellanger, C. - Chiron, D. - Anděra, Ladislav - Kryštof, V. - Strnad, Miroslav - Helman, K. - Klánová, M. - Trněný, M. - Havranek, O. - Klener, P.
    Cyclin dependent kinase 4/6 inhibitor palbociclib synergizes with BCL2 inhibitor venetoclax in experimental models of mantle cell lymphoma without iRB1/i deletion.
    EXP HEMATOL ONCOL. Roč. 13, č. 1 (2024), č. článku 34. E-ISSN 2162-3619
    Institutional support: RVO:86652036 ; RVO:61389030
    Keywords : cdk4/6 * Cyclin-dependent kinase (CDK) inhibitors * Palbociclib * bcl2 * Venetoclax * rb1 * Mantle cell lymphoma (MCL)
    OECD category: Oncology
    Impact factor: 10.9, year: 2022
    Method of publishing: Open access
    https://ehoonline.biomedcentral.com/articles/10.1186/s40164-024-00499-2
    Permanent Link: https://hdl.handle.net/11104/0353392
     
     
  2. 2.
    0579078 - ÚMG 2024 RIV US eng J - Journal Article
    Průková, D. - Anděra, Ladislav - Nahácka, Zuzana - Karolová, J. - Svaton, M. - Klánová, M. - Havránek, O. - Soukup, J. - Svobodová, K. - Zemanová, Z. - Tušková, D. - Pokorná, E. - Helman, K. - Forsterova, K. - Pacheco-Blanco, M. - Vočková, P. - Berková, A. - Froňková, E. - Trněný, M. - Klener, P.
    Cotargeting of BCL2 with Venetoclax and MCL1 with S63845 Is Synthetically Lethal In Vivo in Relapsed Mantle Cell Lymphoma.
    Clinical Cancer Research. Roč. 25, č. 14 (2019), s. 4455-4465. ISSN 1078-0432. E-ISSN 1557-3265
    Institutional support: RVO:68378050
    Keywords : acute myeloid-leukemia * open-label * cancer * landscape * combination * cytarabine * resistance * apoptosis * overcome * abt-199
    OECD category: Biochemistry and molecular biology
    Impact factor: 10.107, year: 2019
    Method of publishing: Limited access
    https://aacrjournals.org/clincancerres/article/25/14/4455/81919/Cotargeting-of-BCL2-with-Venetoclax-and-MCL1-with
    Permanent Link: https://hdl.handle.net/11104/0347951
     
     
  3. 3.
    0557905 - ÚMG 2023 RIV US eng J - Journal Article
    Klánová, M. - Kazantsev, D. - Pokorná, E. - Zikmund, T. - Karolová, J. - Behounek, M. - Renesova, N. - Sovilj, D. - Kelemen, C. - Helman, K. - Jaksa, R. - Havránek, O. - Anděra, Ladislav - Trněný, M. - Klener, P.
    Anti-apoptotic MCL1 Protein Represents Critical Survival Molecule for Most Burkitt Lymphomas and BCL2-negative Diffuse Large B-cell Lymphomas.
    Molecular Cancer Therapeutics. Roč. 21, č. 1 (2022), s. 89-99. ISSN 1535-7163. E-ISSN 1538-8514
    Institutional support: RVO:68378050
    Keywords : gene-expression * elderly-patients * bcl-2 family * venetoclax * chemotherapy * inhibition * mutations * subgroups * abt-199 * dlbcl
    OECD category: Oncology
    Impact factor: 5.7, year: 2022
    Method of publishing: Open access
    https://aacrjournals.org/mct/article/21/1/89/675161/Anti-apoptotic-MCL1-Protein-Represents-Critical
    Permanent Link: http://hdl.handle.net/11104/0331789
     
     
  4. 4.
    0554659 - BTÚ 2023 RIV US eng J - Journal Article
    Klánová, M. - Kazantsev, D. - Pokorná, E. - Zikmund, T. - Karolová, J. - Behounek, M. - Renesova, N. - Sovilj, Dana - Kelemen, Cristina D. - Helman, K. - Jaksa, R. - Havranek, O. - Anděra, Ladislav - Trněný, M. - Klener, P.
    Anti-apoptotic MCL1 Protein Represents Critical Survival Molecule for Most Burkitt Lymphomas and BCL2-negative Diffuse Large B-cell Lymphomas.
    Molecular Cancer Therapeutics. Roč. 21, č. 1 (2022), s. 89-99. ISSN 1535-7163. E-ISSN 1538-8514
    R&D Projects: GA ČR(CZ) GA19-08772S; GA MZd(CZ) NU21-03-00386
    Institutional support: RVO:86652036
    Keywords : gene-expression * elderly-patients * bcl-2 family * venetoclax * chemotherapy
    OECD category: Oncology
    Impact factor: 5.7, year: 2022
    Method of publishing: Open access
    https://aacrjournals.org/mct/article/21/1/89/675161/Anti-apoptotic-MCL1-Protein-Represents-Critical
    Permanent Link: http://hdl.handle.net/11104/0331895
     
     
  5. 5.
    0539323 - ÚEB 2021 RIV CH eng J - Journal Article
    Komárková, M. - Chromý, J. - Pokorná, E. - Soudek, Petr - Máchová, P.
    Physiological and transcriptomic response of grey poplar (Populus × canescens aiton sm.) to cadmium stress.
    Plants. Roč. 9, č. 11 (2020), s. 1-18, č. článku 1485. E-ISSN 2223-7747
    R&D Projects: GA MŠMT(CZ) EF16_019/0000738
    Institutional support: RVO:61389030
    Keywords : Cadmium * Gene expression * Grey poplar * Microsatellite analysis * Mineral uptake * Translocation factor
    OECD category: Biochemical research methods
    Impact factor: 3.935, year: 2020
    Method of publishing: Open access
    http://doi.org/10.3390/plants9111485
    Permanent Link: http://hdl.handle.net/11104/0317010
    FileDownloadSizeCommentaryVersionAccess
    2020_Komarkova_Plants_1485.pdf11 MBOtheropen-access
     
     
  6. 6.
    0536177 - ÚMCH 2022 RIV GB eng J - Journal Article
    Pola, Robert - Pokorná, E. - Vočková, P. - Böhmová, Eliška - Pechar, Michal - Karolová, J. - Pankrác, J. - Šefc, L. - Helman, K. - Trněný, M. - Etrych, Tomáš - Klener, P.
    Cytarabine nanotherapeutics with increased stability and enhanced lymphoma uptake for tailored highly effective therapy of mantle cell lymphoma.
    Acta Biomaterialia. Roč. 119, 1 January (2021), s. 349-359. ISSN 1742-7061. E-ISSN 1878-7568
    R&D Projects: GA ČR(CZ) GA19-01417S; GA MŠMT(CZ) LTAUSA18083; GA MŠMT(CZ) LQ1604
    Institutional support: RVO:61389013
    Keywords : cytarabine * mantle cell lymphoma * nanotherapeutics
    OECD category: Polymer science
    Impact factor: 10.633, year: 2021
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S1742706120306577?via%3Dihub
    Permanent Link: http://hdl.handle.net/11104/0314361
     
     
  7. 7.
    0531974 - ÚMCH 2021 RIV NL eng J - Journal Article
    Lidický, Ondřej - Klener, P. - Machová, Daniela - Vočková, P. - Pokorná, E. - Helman, K. - Mavis, C. - Janoušková, Olga - Etrych, Tomáš
    Overcoming resistance to rituximab in relapsed non-Hodgkin lymphomas by antibody-polymer drug conjugates actively targeted by anti-CD38 daratumumab.
    Journal of Controlled Release. Roč. 328, 10 December (2020), s. 160-170. ISSN 0168-3659. E-ISSN 1873-4995
    R&D Projects: GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT(CZ) LQ1604; GA ČR(CZ) GA19-01417S
    Institutional support: RVO:61389013
    Keywords : non-Hodgkin lymphoma * active targeting * drug delivery
    OECD category: Polymer science
    Impact factor: 9.776, year: 2020
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S0168365920304831?via%3Dihub
    Permanent Link: http://hdl.handle.net/11104/0310714
     
     
  8. 8.
    0521329 - BTÚ 2020 RIV US eng J - Journal Article
    Průková, D. - Anděra, Ladislav - Nahácka, Zuzana - Karolová, J. - Svaton, M. - Klanova, M. - Havranek, O. - Soukup, J. - Svobodová, K. - Zemanová, Z. - Tušková, D. - Pokorná, E. - Helman, K. - Forsterova, K. - Pacheco-Blanco, M. - Vockova, P. - Berková, A. - Froňková, E. - Trněný, M. - Klener, P.
    Cotargeting of BCL2 with Venetoclax and MCL1 with S63845 Is Synthetically Lethal In Vivo in Relapsed Mantle Cell Lymphoma.
    Clinical Cancer Research. Roč. 25, č. 14 (2019), s. 4455-4465. ISSN 1078-0432. E-ISSN 1557-3265
    Institutional support: RVO:86652036
    Keywords : acute myeloid-leukemia * open-label * cancer * landscape
    OECD category: Oncology
    Impact factor: 10.107, year: 2019
    Method of publishing: Open access
    https://clincancerres.aacrjournals.org/content/25/14/4455
    Permanent Link: http://hdl.handle.net/11104/0305960
     
     
  9. 9.
    0493938 - ÚMCH 2019 RIV NL eng J - Journal Article
    Etrych, Tomáš - Daumová, L. - Pokorná, E. - Tušková, D. - Lidický, Ondřej - Kolářová, V. - Pankrác, J. - Šefc, L. - Chytil, Petr - Klener, P.
    Effective doxorubicin-based nano-therapeutics for simultaneous malignant lymphoma treatment and lymphoma growth imaging.
    Journal of Controlled Release. Roč. 289, 10 November (2018), s. 44-55. ISSN 0168-3659. E-ISSN 1873-4995
    R&D Projects: GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT(CZ) LO1507; GA ČR(CZ) GA17-13283S
    Institutional support: RVO:61389013
    Keywords : malignant lymphoma * HPMA copolymers * drug delivery systems
    OECD category: Polymer science
    Impact factor: 7.901, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0287383
     
     


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