Search results
- 1.0587109 - ÚEM 2025 RIV NL eng J - Journal Article
Chvojková, M. - Kolář, D. - Kováčová, K. - Čejková, L. - Misiachna, Anna - Hakenová, K. - Gorecki, L. - Horák, Martin - Korabecný, J. - Soukup, O. - Valeš, K.
Pro-cognitive effects of dual tacrine derivatives acting as cholinesterase inhibitors and NMDA receptor antagonists.
Biomedicine & Pharmacotherapy. Roč. 176, July (2024), č. článku 116821. ISSN 0753-3322. E-ISSN 1950-6007
R&D Projects: GA MŠMT(CZ) LX22NPO5107; GA MŠMT(CZ) EH22_008/0004562
Institutional support: RVO:68378041
Keywords : acetylcholinesterase * alzheimer disease * cognition * polypharmacology * receptors * N-Methyl-D-Aspartate * tacrine
OECD category: Neurosciences (including psychophysiology
Impact factor: 7.5, year: 2022
https://www.sciencedirect.com/science/article/pii/S0753332224007054?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0354401File Download Size Commentary Version Access Chvojková 2024.pdf 0 1.8 MB Publisher’s postprint open-access - 2.0584241 - ÚEM 2025 RIV NL eng J - Journal Article
Mezeiová, E. - Prchal, L. - Hrabinová, M. - Mucková, L. - Pulkrabková, L. - Soukup, O. - Misiachna, Anna - Janoušek, J. - Fibigar, J. - Kučera, T. - Horák, Martin - Makhaeva, G.F. - Korabecný, J.
Morphing cholinesterase inhibitor amiridine into multipotent drugs for the
treatment of Alzheimer’s disease.
Biomedicine & Pharmacotherapy. Roč. 173, april. (2024), č. článku 116399. ISSN 0753-3322. E-ISSN 1950-6007
R&D Projects: GA ČR(CZ) GA22-24384S; GA MŠMT(CZ) EH22_008/0004562
Institutional support: RVO:68378041
Keywords : amiridine * acetylcholinesterase * antioxidant capacity * butyrylcholinesterase * multi-target directed ligands * NMDA receptors
OECD category: Neurosciences (including psychophysiology
Impact factor: 7.5, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S075333222400283X?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0352201File Download Size Commentary Version Access Mezeirová 2024.pdf 3 1.7 MB Publisher’s postprint open-access - 3.0584110 - ÚMCH 2025 RIV GB eng J - Journal Article
Hoang, Stéphane - Zhukouskaya, Hanna - Ivanko, Iryna - Svoboda, Jan - Hympánová, M. - Marek, J. - Soukup, O. - Šlouf, Miroslav - Kotek, J. - Doris, E. - Gravel, E. - Tomšík, Elena - Hrubý, Martin
Improved electro-destruction of bacterial biofilms by coating conductive surfaces with polymers.
European Polymer Journal. Roč. 209, 15 April (2024), č. článku 112910. ISSN 0014-3057. E-ISSN 1873-1945
R&D Projects: GA ČR(CZ) GA21-01090S; GA MŠMT(CZ) LUAUS24272; GA MŠMT(CZ) EH22_008/0004607
Institutional support: RVO:61389013
Keywords : bacteria * biofilm * polymer
OECD category: Polymer science
Impact factor: 6, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S001430572400171X?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0352482 - 4.0582133 - ÚEM 2025 RIV NL eng J - Journal Article
Misiachna, Anna - Svobodová, B. - Netolický, Jakub - Chvojková, M. - Kletečková, L. - Prchal, L. - Novák, M. - Hrabinová, M. - Kučera, T. - Mucková, L. - Moravcová, Z. - Karasová-Ždárová, J. - Pejchal, J. - Blažek, F. - Maliňák, D. - Hakenová, K. - Hrčka Krausová, Barbora - Kolcheva, Marharyta - Ladislav, Marek - Korábečný, J. - Pahnke, J. - Valeš, K. - Horák, Martin - Soukup, O.
Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition.
European Journal of Medicinal Chemistry. Roč. 266, feb. (2024), č. článku 116130. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA TA ČR(CZ) TO01000078; GA MŠMT(CZ) EH22_008/0004562
Institutional support: RVO:68378041
OECD category: Neurosciences (including psychophysiology
Impact factor: 6.7, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0223523424000102?via%3Dihub https://doi.org/10.5281/zenodo.10949371 https://doi.org/10.2139/ssrn.4658299
Permanent Link: https://hdl.handle.net/11104/0350209File Download Size Commentary Version Access Misiachna příloha 2024.pdf 1 9.8 MB Other open-access Misiachna 2024.pdf 4 5 MB Publisher’s postprint open-access - 5.0573825 - FGÚ 2024 RIV GB eng J - Journal Article
Vojtěchová, Iveta - Tučková, K. - Jůza, R. - Stuchlík, Aleš - Kelemen, E. - Korábečný, J. - Soukup, O. - Petrásek, Tomáš
Dopaminergic and glutamatergic models of psychosis show differential sensitivity to aripiprazole and a novel experimental compound modulating D2/5-HT receptor activity.
Progress in Neuro-Psychopharmacology & Biological Psychiatry. Roč. 127, 20 Dec (2023), č. článku 110819. ISSN 0278-5846. E-ISSN 1878-4216
R&D Projects: GA MZd(CZ) NU22-04-00526
Institutional support: RVO:67985823
Keywords : schizophrenia * dizocilpine * amphetamine * antipsychotic * aripiprazole
OECD category: Neurosciences (including psychophysiology
Impact factor: 5.6, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.pnpbp.2023.110819
Permanent Link: https://hdl.handle.net/11104/0344177 - 6.0572189 - ÚEM 2024 RIV CH eng J - Journal Article
Svobodová, B. - Pulkrabová, L. - Pánek, D. - Misiachna, Anna - Kolcheva, Marharyta - Andrýs, R. - Handl, J. - Čapek, J. - Nývltová, P. - Roušar, T. - Prchal, L. - Hepnarová, V. - Hrabinová, M. - Mucková, L. - Tosnerová, D. - Karabanovich, G. - Finger, V. - Soukup, O. - Horák, Martin - Korabecný, J.
Structure-Guided Design of N-Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer’s Disease.
International Journal of Molecular Sciences. Roč. 24, č. 11 (2023), č. článku 9124. ISSN 1661-6596
R&D Projects: GA ČR(CZ) GA22-24384S; GA MŠMT(CZ) LX22NPO5107
Institutional support: RVO:68378041
Keywords : Alzheimer’s disease * acetylcholinesterase * enzyme inhibition * N-methyl-d-aspartate receptor * multi-target directed ligands * monoamine oxidase A/B
OECD category: Pharmacology and pharmacy
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://doi.org/10.3390/ijms24119124
Permanent Link: https://hdl.handle.net/11104/0342960File Download Size Commentary Version Access Svobodová 2023.pdf 2 3.8 MB Publisher’s postprint open-access - 7.0559439 - ÚMG 2023 RIV FR eng J - Journal Article
Gorecki, L. - Muthna, D. - Merdita, S. - Andrš, Martin - Kučera, T. - Havelek, R. - Mucková, L. - Kobrlová, T. - Soukup, J. - Krupa, P. - Prchal, L. - Soukup, O. - Roh, J. - Řezáčová, M. - Korábečný, J.
7-Azaindole, 2,7-diazaindole, and 1H-pyrazole as core structures for novel anticancer agents with potential chemosensitizing properties.
European Journal of Medicinal Chemistry. Roč. 240, June (2022), č. článku 114580. ISSN 0223-5234. E-ISSN 1768-3254
Institutional support: RVO:68378050
Keywords : ATR inhibition * Berzosertib * Cancer * Chemosensitization * Cytotoxicity * Glioblastoma
OECD category: Cell biology
Impact factor: 6.7, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/abs/pii/S0223523422004822?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0332860 - 8.0556370 - FGÚ 2023 RIV FR eng J - Journal Article
Jůza, R. - Vojtěchová, I. - Štefková-Mazochová, K. - Dehaen, W. - Petrásek, T. - Prchal, L. - Kobrlová, T. - Janoušek, J. - Vlček, P. - Mezeiová, E. - Svozil, D. - Zdarová Karasová, J. - Pejchal, J. - Stark, H. - Satala, G. - Bojarski, A. J. - Kubacka, M. - Mogilski, S. - Randáková, Alena - Musílek, K. - Soukup, O. - Korábečný, J.
Novel D-2/5-HT receptor modulators related to cariprazine with potential implication to schizophrenia treatment.
European Journal of Medicinal Chemistry. Roč. 232, Mar 15 (2022), č. článku 114193. ISSN 0223-5234. E-ISSN 1768-3254
Institutional support: RVO:67985823
Keywords : aripiprazole * cariprazine * dopamine type 2 receptor * drug development * serotonin receptor type 3 * schizophrenia * 1,4-Di-substituted aromatic piperazines * antipsychotic
OECD category: Pharmacology and pharmacy
Impact factor: 6.7, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.ejmech.2022.114193
Permanent Link: http://hdl.handle.net/11104/0330742 - 9.0551558 - ÚEM 2022 RIV FR eng J - Journal Article
Gorecki, L. - Misiachna, Anna - Damborský, J. - Doležal, R. - Korábečný, J. - Čejková, L. - Hakenová, K. - Chvojková, M. - Zdarová Karasová, J. - Prchal, L. - Novák, M. - Kolcheva, Marharyta - Kortus, Štěpán - Valeš, K. - Horák, Martin - Soukup, O.
Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-D-Aspartate receptors.
European Journal of Medicinal Chemistry. Roč. 219, 5 july (2021), č. článku 113434. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA ČR(CZ) GA20-12047S; GA TA ČR(CZ) TO01000078
Institutional support: RVO:68378041
Keywords : QSAR * acetylcholinesterase * electrophysiology * glutamate receptor * ion channel * pharmacologyin vivo * tacrine
OECD category: Medicinal chemistry
Impact factor: 7.088, year: 2021
Method of publishing: Open access
https://doi.org/10.1016/j.ejmech.2021.113434
Permanent Link: http://hdl.handle.net/11104/0326821 - 10.0546462 - FGÚ 2022 RIV CH eng J - Journal Article
Jůza, R. - Štefková, K. - Dehaen, W. - Randáková, Alena - Petrásek, T. - Vojtěchová, I. - Kobrlová, T. - Pulkrábková, L. - Mucková, L. - Mecava, M. - Prchal, L. - Mezeiová, E. - Musílek, K. - Soukup, O. - Korábečný, J.
Synthesis and In Vitro Evaluation of Novel Dopamine Receptor D-2 3,4-dihydroquinolin-2(1H)-one Derivatives Related to Aripiprazole.
Biomolecules. Roč. 11, č. 9 (2021), č. článku 1262. E-ISSN 2218-273X
Institutional support: RVO:67985823
Keywords : aripiprazole * dopamine receptor * blood–brain barrier * molecular modeling studies * schizophrenia
OECD category: Pharmacology and pharmacy
Impact factor: 6.064, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2218-273X/11/9/1262
Permanent Link: http://hdl.handle.net/11104/0322976