Search results
- 1.0463545 - ÚOCHB 2017 RIV US eng J - Journal Article
Plačková, Pavla - Šála, Michal - Šmídková, Markéta - Dejmek, Milan - Hřebabecký, Hubert - Nencka, Radim - Thibaut, H. J. - Neyts, J. - Mertlíková-Kaiserová, Helena
9-Norbornyl-6-chloropurine (NCP) induces cell death through GSH depletion-associated ER stress and mitochondrial dysfunction.
Free Radical Biology and Medicine. Roč. 97, Aug (2016), s. 223-235. ISSN 0891-5849. E-ISSN 1873-4596
R&D Projects: GA MŠMT LO1302; GA ČR GAP303/11/1297
Institutional support: RVO:61388963
Keywords : glutathione-S-transferase * oxidative stress * leukemia
Subject RIV: CE - Biochemistry
Impact factor: 5.606, year: 2016
http://www.sciencedirect.com/science/article/pii/S0891584916302921
Permanent Link: http://hdl.handle.net/11104/0262713File Download Size Commentary Version Access 0463545.pdf 5 2 MB Publisher’s postprint open-access - 2.0443259 - ÚOCHB 2016 RIV GB eng J - Journal Article
Plačková, Pavla - Hřebabecký, Hubert - Šála, Michal - Nencka, Radim - Elbert, Tomáš - Mertlíková-Kaiserová, Helena
Transport mechanisms of a novel antileukemic and antiviral compound 9-norbornyl-6-chloropurine.
Journal of Enzyme Inhibition and Medicinal Chemistry. Roč. 30, č. 1 (2015), s. 57-62. ISSN 1475-6366. E-ISSN 1475-6374
R&D Projects: GA ČR GAP303/11/1297
Institutional support: RVO:61388963
Keywords : carbocyclic nucleoside analogs * CCRF-CEM cells * facilitated diffusion * MRP proteins * P-glycoprotein
Subject RIV: CE - Biochemistry
Impact factor: 3.428, year: 2015
Permanent Link: http://hdl.handle.net/11104/0246048 - 3.0430390 - ÚOCHB 2015 RIV DE eng J - Journal Article
Dejmek, Milan - Šála, Michal - Plačková, Pavla - Hřebabecký, Hubert - Borreda, L. M. - Neyts, J. - Dračínský, Martin - Procházková, Eliška - Jansa, Petr - Leyssen, P. - Mertlíková-Kaiserová, Helena - Nencka, Radim
Synthesis of Novel Purine-Based Coxsackievirus Inhibitors Bearing Polycylic Substituents at the N-9 Position.
Archiv der Pharmazie. Roč. 347, č. 7 (2014), s. 478-485. ISSN 0365-6233. E-ISSN 1521-4184
R&D Projects: GA ČR GAP303/11/1297
Institutional support: RVO:61388963
Keywords : antiviral * coxsackievirus B3 * enteroviruses * phosphatidylinositol 4-kinase (PI4K) * purines
Subject RIV: CC - Organic Chemistry
Impact factor: 1.531, year: 2014
Permanent Link: http://hdl.handle.net/11104/0235359 - 4.0396057 - ÚOCHB 2014 RIV GR eng J - Journal Article
Plačková, Pavla - Rozumová, N. - Hřebabecký, Hubert - Šála, Michal - Nencka, Radim - Elbert, Tomáš - Dvořáková, Alexandra - Votruba, Ivan - Mertlíková-Kaiserová, Helena
9-Norbornyl-6-chloropurine Is a Novel Antileukemic Compound Interacting with Cellular GSH.
Anticancer Research. Roč. 33, č. 8 (2013), s. 3163-3168. ISSN 0250-7005. E-ISSN 1791-7530
R&D Projects: GA ČR GAP303/11/1297
Institutional support: RVO:61388963
Keywords : Substituted 6-chloropurines * carbocyclic nucleoside analogs * glutathione-S-transferase * glutathione depletion
Subject RIV: FD - Oncology ; Hematology
Impact factor: 1.872, year: 2013
Permanent Link: http://hdl.handle.net/11104/0223911 - 5.0376557 - ÚOCHB 2013 RIV GB eng J - Journal Article
Hřebabecký, Hubert - Dejmek, Milan - Šála, Michal - Mertlíková-Kaiserová, Helena - Dračínský, Martin - Leyssen, P. - Neyts, J. - Nencka, Radim
Synthesis of novel thienonorbornylpurine derivatives.
Tetrahedron. Roč. 68, č. 15 (2012), s. 3195-3204. ISSN 0040-4020. E-ISSN 1464-5416
R&D Projects: GA ČR GAP303/11/1297; GA MŠMT 1M0508
Institutional research plan: CEZ:AV0Z40550506
Keywords : hepatitis virus * Coxsackie virus * sulfur heterocycles
Subject RIV: CC - Organic Chemistry
Impact factor: 2.803, year: 2012
Permanent Link: http://hdl.handle.net/11104/0208925 - 6.0376440 - ÚOCHB 2013 RIV GB eng J - Journal Article
Šála, Michal - Hřebabecký, Hubert - Leyssen, P. - Dejmek, Milan - Dračínský, Martin - De Palma, A. M. - Neyts, J. - Nencka, Radim
Novel substituted 9-norbornylpurines and their activities against RNA viruses.
Bioorganic and Medicinal Chemistry Letters. Roč. 22, č. 5 (2012), s. 1963-1968. ISSN 0960-894X. E-ISSN 1464-3405
R&D Projects: GA ČR GAP303/11/1297; GA MŠMT 1M0508
Grant - others:FP7 SILVER(XE) 260644
Institutional research plan: CEZ:AV0Z40550506
Keywords : antiviral * coxsackievirus * norbornane * picornaviruses * purine
Subject RIV: CC - Organic Chemistry
Impact factor: 2.338, year: 2012
Permanent Link: http://hdl.handle.net/11104/0208836 - 7.0360813 - ÚOCHB 2012 RIV GB eng J - Journal Article
Šála, Michal - De Palma, A. M. - Hřebabecký, Hubert - Dejmek, Milan - Dračínský, Martin - Leyssen, P. - Neyts, J. - Mertlíková-Kaiserová, Helena - Nencka, Radim
SAR studies of 9-norbornylpurines as Coxsackievirus B3 inhibitors.
Bioorganic and Medicinal Chemistry Letters. Roč. 21, č. 14 (2011), s. 4271-4275. ISSN 0960-894X. E-ISSN 1464-3405
R&D Projects: GA MŠMT 1M0508; GA ČR GAP303/11/1297
Institutional research plan: CEZ:AV0Z40550506
Keywords : coxsackievirus * norbornane * picornaviruses
Subject RIV: CC - Organic Chemistry
Impact factor: 2.554, year: 2011
Permanent Link: http://hdl.handle.net/11104/0198276