Search results
- 1.0461356 - ÚOCHB 2017 RIV US eng J - Journal Article
Perlíková, Pavla - Rylová, G. - Nauš, Petr - Elbert, Tomáš - Tloušťová, Eva - Bourderioux, Aurelie - Poštová Slavětínská, Lenka - Motyka, K. - Doležal, D. - Znojek, P. - Nová, A. - Harvanová, M. - Džubák, P. - Šiller, M. - Hlaváč, J. - Hajdúch, M. - Hocek, Michal
7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action.
Molecular Cancer Therapeutics. Roč. 15, č. 5 (2016), s. 922-937. ISSN 1535-7163. E-ISSN 1538-8514
R&D Projects: GA ČR GAP207/11/0344; GA TA ČR(CZ) TE01020028; GA MŠMT(CZ) LO1304
Institutional support: RVO:61388963
Keywords : sugar-modified derivatives * cross-coupling reactions * ribosomal RNA synthesis
Subject RIV: CC - Organic Chemistry
Impact factor: 5.764, year: 2016
Permanent Link: http://hdl.handle.net/11104/0260969 - 2.0436116 - ÚOCHB 2015 RIV US eng J - Journal Article
Snášel, Jan - Nauš, Petr - Dostál, Jiří - Hnízda, Aleš - Fanfrlík, Jindřich - Brynda, Jiří - Bourderioux, Aurelie - Dušek, Michal - Dvořáková, H. - Stolaříková, J. - Zábranská, Helena - Pohl, Radek - Konečný, P. - Džubák, P. - Votruba, Ivan - Hajdúch, M. - Řezáčová, Pavlína - Veverka, Václav - Hocek, Michal - Pichová, Iva
Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides.
Journal of Medicinal Chemistry. Roč. 57, č. 20 (2014), s. 8268-8279. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR GAP207/11/0344; GA MŠMT LO1302; GA MŠMT(CZ) LK11205
EU Projects: European Commission(XE) 241587 - SYSTEMTB
Grant - others:GA MŠk(CZ) LM2011020
Institutional support: RVO:61388963 ; RVO:68378271
Keywords : 7-(het)aryl-7-deazaadenine ribonucleosides * enzyme inhibition * adenosine kinase * cytostatic activity
Subject RIV: CC - Organic Chemistry
Impact factor: 5.447, year: 2014
Permanent Link: http://hdl.handle.net/11104/0239959 - 3.0382173 - ÚOCHB 2013 RIV GB eng J - Journal Article
Nauš, Petr - Perlíková, Pavla - Bourderioux, Aurelie - Pohl, Radek - Slavětínská, Lenka - Votruba, Ivan - Bahador, G. - Birkuš, G. - Cihlář, T. - Hocek, Michal
Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2'-C-methylribonucleosides, 2'-deoxy-2'-fluoroarabinonucleosides, arabinonucleosides and 2'-deoxyribonucleosides.
Bioorganic & Medicinal Chemistry. Roč. 20, č. 17 (2012), s. 5202-5214. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA ČR GAP207/11/0344
Institutional support: RVO:61388963
Keywords : nucleosides * deazapurines * cytostatics
Subject RIV: CC - Organic Chemistry
Impact factor: 2.903, year: 2012
Permanent Link: http://hdl.handle.net/11104/0212470 - 4.0364270 - ÚOCHB 2012 RIV US eng J - Journal Article
Bourderioux, Aurelie - Nauš, Petr - Perlíková, Pavla - Pohl, Radek - Pichová, Iva - Votruba, Ivan - Džubák, P. - Konečný, P. - Hajdúch, M. - Stray, K. M. - Wang, T. - Ray, A. S. - Feng, J. Y. - Birkuš, G. - Cihlar, T. - Hocek, Michal
Synthesis and Significant Cytostatic Activity of 7-Hetaryl-7-deazaadenosines.
Journal of Medicinal Chemistry. Roč. 54, č. 15 (2011), s. 5498-5507. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT 1M0508; GA ČR GAP207/11/0344
Grant - others:GA MŠk(CZ) LC07017
Program: LC
Institutional research plan: CEZ:AV0Z40550506
Keywords : adenosine-kinase-inhibitors * cross-coupling reactions * cytotoxic nucleoside analogs * enzyme-inhibition * ribonucleosides
Subject RIV: CC - Organic Chemistry
Impact factor: 5.248, year: 2011
Permanent Link: http://hdl.handle.net/11104/0199795