Search results
- 1.0581608 - ÚOCHB 2025 RIV GB eng J - Journal Article
Formánek, B. - Dupommier, D. - Volfová, T. - Rimpelová, S. - Škarková, A. - Herciková, J. - Rösel, D. - Brábek, J. - Perlíková, Pavla
Synthesis and migrastatic activity of cytochalasin analogues lacking a macrocyclic moiety.
RSC MEDICINAL CHEMISTRY. Roč. 15, č. 1 (2024), s. 322-343. E-ISSN 2632-8682
R&D Projects: GA MŠMT LX22NPO5102
Institutional support: RVO:61388963
Keywords : actin polymerization * cellular structures * alkyl-halides
Impact factor: 4.1, year: 2022
Method of publishing: Open access
https://doi.org/10.1039/D3MD00535F
Permanent Link: https://hdl.handle.net/11104/0349710File Download Size Commentary Version Access 10.1039D3MD00535F.pdf 0 2.3 MB Publisher’s postprint open-access - 2.0563157 - ÚOCHB 2023 RIV US eng J - Journal Article
Vavřina, Zdeněk - Perlíková, Pavla - Milisavljevič, Nemanja - Chevrier, Florian - Smola, Miroslav - Smith, Joshua - Dejmek, Milan - Havlíček, Vojtěch - Buděšínský, Miloš - Liboska, Radek - Vaneková, Lenka - Brynda, Jiří - Bouřa, Evžen - Řezáčová, Pavlína - Hocek, Michal - Birkuš, Gabriel
Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists.
Journal of Medicinal Chemistry. Roč. 65, č. 20 (2022), s. 14082-14103. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT LX22NPO5102; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : GMP-AMP synthase * interferon genes * adapter protein
OECD category: Biochemistry and molecular biology
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acs.jmedchem.2c01305
Permanent Link: https://hdl.handle.net/11104/0335201File Download Size Commentary Version Access 10.1021acs.jmedchem.2c01305.pdf 5 6.9 MB Publisher’s postprint open-access - 3.0541879 - ÚOCHB 2022 RIV US eng J - Journal Article
Perlíková, Pavla - Krajczyk, Anna - Doleželová, Eva - Slapničková, Martina - Milisavljevič, Nemanja - Poštová Slavětínská, Lenka - Tloušťová, Eva - Gurská, S. - Džubák, P. - Hajdúch, M. - Zíková, Alena - Hocek, Michal
Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides.
ACS Infectious Diseases. Roč. 7, č. 4 (2021), s. 917-926. ISSN 2373-8227
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) EF16_019/0000759; GA ČR(CZ) GA19-08124S; GA ČR(CZ) GA19-07707S; GA MŠMT(CZ) LM2015064
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : nucleosides * antiparasitic activity * antitrypanosomal * cytotoxicity
OECD category: Organic chemistry; Organic chemistry (BC-A)
Impact factor: 5.578, year: 2021
Method of publishing: Limited access
https://doi.org/10.1021/acsinfecdis.1c00062
Permanent Link: http://hdl.handle.net/11104/0319376 - 4.0541252 - ÚOCHB 2022 RIV CZ cze J - Journal Article
Perlíková, Pavla
Aryl-7-deazapurinové nukleosidy a jejich biologická aktivita.
[Aryl-7-deazapurine Nucleosides and their Biological Activity.]
Chemické listy. Roč. 115, č. 2 (2021), s. 84-90. ISSN 0009-2770. E-ISSN 1213-7103
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : nucleoside * 7-deazapurine * cytotoxicity * adenosine kinase
OECD category: Organic chemistry
Impact factor: 0.356, year: 2021
Method of publishing: Open access
http://www.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/3790
Permanent Link: http://hdl.handle.net/11104/0318840 - 5.0532766 - ÚOCHB 2021 RIV DE eng J - Journal Article
Veselovská, Lucia - Kudlová, N. - Gurská, S. - Lišková, B. - Medvedíková, M. - Hodek, Ondřej - Tloušťová, Eva - Milisavljevič, Nemanja - Tichý, Michal - Perlíková, Pavla - Mertlíková-Kaiserová, Helena - Trylčová, Jana - Pohl, Radek - Klepetářová, Blanka - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis and Cytotoxic and Antiviral Activity Profiling of All-Four Isomeric Series of Pyrido-Fused 7-Deazapurine Ribonucleosides.
Chemistry - A European Journal. Roč. 26, č. 57 (2020), s. 13002-13015. ISSN 0947-6539. E-ISSN 1521-3765
R&D Projects: GA ČR(CZ) GA19-08124S; GA MZd(CZ) NV15-31984A; GA MŠMT(CZ) LM2015064
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : antitumor agents * antiviral agents * drug discovery * phosphorylation * ribonucleosides
OECD category: Organic chemistry
Impact factor: 5.236, year: 2020
Method of publishing: Limited access
https://doi.org/10.1002/chem.202001124
Permanent Link: http://hdl.handle.net/11104/0311179 - 6.0511505 - ÚOCHB 2020 RIV US eng J - Journal Article
Perlíková, Pavla - Kvasnica, Miroslav - Urban, M. - Hajdúch, M. - Šarek, J.
2-Deoxyglycoside Conjugates of Lupane Triterpenoids with High Cytotoxic Activity—Synthesis, Activity, and Pharmacokinetic Profile.
Bioconjugate Chemistry. Roč. 30, č. 11 (2019), s. 2844-2858. ISSN 1043-1802. E-ISSN 1520-4812
R&D Projects: GA MPO(CZ) FV10599; GA ČR(CZ) GA19-01383S; GA MŠMT(CZ) EF16_019/0000827
Institutional support: RVO:61388963 ; RVO:61389030
Keywords : betulinic acid * stereoselective synthesis * antiviral activity
OECD category: Organic chemistry
Impact factor: 4.031, year: 2019
Method of publishing: Limited access
https://pubs.acs.org/doi/abs/10.1021/acs.bioconjchem.9b00565
Permanent Link: http://hdl.handle.net/11104/0301752File Download Size Commentary Version Access 2019_Perlikova_Bioconjugate Chemistry_2844.pdf 3 1.8 MB Other open-access - 7.0498520 - ÚOCHB 2019 RIV US eng J - Journal Article
Tokarenko, Anna - Lišková, B. - Smolen, Sabina - Táborská, N. - Tichý, Michal - Gurská, S. - Perlíková, Pavla - Frydrych, I. - Tloušťová, Eva - Znojek, P. - Mertlíková-Kaiserová, Helena - Poštová Slavětínská, Lenka - Pohl, Radek - Klepetářová, Blanka - Khalid, N. U. A. - Wenren, Y. - Laposa, R. R. - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides.
Journal of Medicinal Chemistry. Roč. 61, č. 20 (2018), s. 9347-9359. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR(CZ) GA16-00178S; GA TA ČR(CZ) TE01020028; GA MŠMT(CZ) LO1304; GA MŠMT(CZ) LM2015064
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : hepatitis C virus * adenosine kinase inhibitors * mitochondrial RNA polymerase
OECD category: Organic chemistry
Impact factor: 6.054, year: 2018
https://pubs.acs.org/doi/full/10.1021/acs.jmedchem.8b01258
Permanent Link: http://hdl.handle.net/11104/0291128File Download Size Commentary Version Access 0498520.pdf 9 1.9 MB Publisher’s postprint open-access - 8.0495509 - ÚOCHB 2019 RIV DE eng J - Journal Article
Ghosh, Ketaki - Perlíková, Pavla - Havlíček, Vojtěch - Yang, Chao - Pohl, Radek - Tloušťová, Eva - Hodek, Jan - Gurská, S. - Džubák, P. - Hajdúch, M. - Hocek, Michal
Isomeric Naphtho-Fused 7-Deazapurine Nucleosides and Nucleotides: Synthesis, Biological Activity, Photophysical Properties and Enzymatic Incorporation to Nucleic Acids.
European Journal of Organic Chemistry. Roč. 2018, č. 37 (2018), s. 5092-5108. ISSN 1434-193X. E-ISSN 1099-0690
R&D Projects: GA ČR(CZ) GA16-00178S; GA TA ČR(CZ) TE01020028; GA MŠMT(CZ) LO1304; GA MŠMT(CZ) LM2015064
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : nucleosides * nucleotides * fused heterocycles * cytostatics * antiviral agents
OECD category: Organic chemistry
Impact factor: 3.029, year: 2018
Permanent Link: http://hdl.handle.net/11104/0288477 - 9.0492887 - ÚOCHB 2019 RIV GB eng J - Journal Article
Milisavljevič, Nemanja - Perlíková, Pavla - Pohl, Radek - Hocek, Michal
Enzymatic synthesis of base-modified RNA by T7 RNA polymerase. A systematic study and comparison of 5-substituted pyrimidine and 7-substituted 7-deazapurine nucleoside triphosphates as substrates.
Organic & Biomolecular Chemistry. Roč. 16, č. 32 (2018), s. 5800-5807. ISSN 1477-0520. E-ISSN 1477-0539
R&D Projects: GA ČR GBP206/12/G151; GA MŠMT(CZ) EF16_019/0000729
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : in vitro selection * unnatural base * nucleic acids
OECD category: Biochemistry and molecular biology
Impact factor: 3.490, year: 2018
Method of publishing: Open access
http://pubs.rsc.org/en/content/articlehtml/2018/ob/c8ob01498a
Permanent Link: http://hdl.handle.net/11104/0286349 - 10.0480866 - ÚOCHB 2018 RIV US eng J - Journal Article
Perlíková, Pavla - Hocek, Michal
Pyrrolo[2,3-d]pyrimidine (7-deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides.
Medicinal Research Reviews. Roč. 37, č. 6 (2017), s. 1429-1460. ISSN 0198-6325. E-ISSN 1098-1128
R&D Projects: GA ČR(CZ) GA16-00178S
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : antivirals * cytostatics * deazapurines * nucleosides * nucleotides
OECD category: Organic chemistry
Impact factor: 8.290, year: 2017
http://onlinelibrary.wiley.com/doi/10.1002/med.21465/full
Permanent Link: http://hdl.handle.net/11104/0276543File Download Size Commentary Version Access 0480866.pdf 3 1.3 MB Publisher’s postprint open-access