Search results
- 1.0541026 - ÚEB 2022 RIV CZ eng J - Journal Article
Spicakova, A. - Kraus, Petr - Gucký, Tomáš - Kryštof, Vladimír - Strnad, Miroslav - Bazgier, V. - Otyepka, M. - Kubickova, V. - Poruba, M. - Rácová, Z. - Zapletalová, I. - Anzenbacher, P.
in vitro and in silico Studies of Interaction of Synthetic 2,6,9-Trisubstituted Purine Kinase Inhibitors BPA-302, BP-21 and BP-117 With Liver Drug-Metabolizing Cytochromes P450.
Physiological Research. Roč. 69, SEP (2020), s. 627-636. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA MZd(CZ) NV17-28231A
Institutional support: RVO:61389030
Keywords : r-roscovitine * cell-cycle * cancer * series * Cytochrome P450 inhibition * High performance liquid chromatography * Cyclin-dependent kinase inhibitor * FLT3-ITD inhibitor * Drug metabolism
OECD category: Organic chemistry
Impact factor: 1.881, year: 2020
Method of publishing: Open access
https://www.biomed.cas.cz/physiolres/pdf/2020/69_S627.pdf
Permanent Link: http://hdl.handle.net/11104/0318600File Download Size Commentary Version Access 2020_Spicakova_Physiological Research_S627.pdf 1 2.5 MB Other open-access - 2.0524406 - ÚEB 2021 RIV US eng J - Journal Article
Gupta, S. - Hrdlička, Jakub - Ngoroyemoto, N. - Nemahunguni, N. K. - Gucký, Tomáš - Novák, Ondřej - Kulkarni, M. G. - Doležal, Karel - Van Staden, J.
Preparation and Standardisation of Smoke-Water for Seed Germination and Plant Growth Stimulation.
Journal of Plant Growth Regulation. Roč. 39, č. 1 (2020), s. 338-345. ISSN 0721-7595. E-ISSN 1435-8107
R&D Projects: GA MŠMT(CZ) EF16_019/0000827
Institutional support: RVO:61389030
Keywords : Grand Rapids * Karrikinolide * Smoke apparatus * Smoke-water * uhplc-esi(+)-ms/ms
OECD category: Biochemistry and molecular biology
Impact factor: 4.169, year: 2020
Method of publishing: Open access
http://doi.org/10.1007/s00344-019-09985-y
Permanent Link: http://hdl.handle.net/11104/0308770File Download Size Commentary Version Access 2020_Gupta_JOURNAL OF PLANT GROWTH REGULATION_338.pdf 1 929.3 KB Other open-access - 3.0512138 - ÚEB 2020 RIV FR eng J - Journal Article
Řezníčková, Eva - Gucký, Tomáš - Kováčová, Veronika - Ajani, Haresh - Jorda, Radek - Kryštof, Vladimír
Activity of 2,6,9-trisubstituted purines as potent PDGFRα kinase inhibitors with antileukaemic activity.
European Journal of Medicinal Chemistry. Roč. 182, Nov 15 (2019), č. článku 111663. ISSN 0223-5234. E-ISSN 1768-3254
Institutional support: RVO:61389030 ; RVO:61388963
Keywords : Acute myeloid leukaemia * Eosinophilic leukaemia * Kinase inhibitor * PDGFRα
OECD category: Hematology
Impact factor: 5.573, year: 2019
Method of publishing: Limited access
http://dx.doi.org/10.1016/j.ejmech.2019.111663
Permanent Link: http://hdl.handle.net/11104/0302348File Download Size Commentary Version Access 2019_Reznickova_European Journal of Medicinal Chemistry_111663.pdf 3 2.9 MB Other require - 4.0507849 - ÚEB 2020 RIV GB eng J - Journal Article
Hrdlička, Jakub - Gucký, Tomáš - Novák, Ondřej - Kulkarni, M. - Gupta, S. - Van Staden, J. - Doležal, Karel
Quantification of karrikins in smoke water using ultra-high performance liquid chromatography-tandem mass spectrometry.
Plant Methods. Roč. 15, JUL 25 (2019), č. článku 81. E-ISSN 1746-4811
R&D Projects: GA MŠMT(CZ) EF16_019/0000827
Institutional support: RVO:61389030
Keywords : Karrikins * Smoke water * Standard addition method * Standard dilution method * Tandem mass spectrometry (MS/MS) * Ultra-high performance liquid chromatography (UHPLC)
OECD category: Biochemistry and molecular biology
Impact factor: 3.610, year: 2019
Method of publishing: Open access
http://dx.doi.org/10.1186/s13007-019-0467-z
Permanent Link: http://hdl.handle.net/11104/0298810File Download Size Commentary Version Access 2019_Hrdlicka_PLANT METHODS_81.pdf 0 1.5 MB Other open-access - 5.0505428 - ÚEB 2020 RIV DE eng J - Journal Article
Béres, T. - Černochová, L. - Ćavar Zeljković, S. - Benická, S. - Gucký, Tomáš - Berčák, M. - Tarkowski, P.
Intralaboratory comparison of analytical methods for quantification of major phytocannabinoids.
Analytical and Bioanalytical Chemistry. Roč. 411, č. 14 (2019), s. 3069-3079. ISSN 1618-2642. E-ISSN 1618-2650
R&D Projects: GA MŠMT(CZ) EF16_019/0000827
Institutional support: RVO:61389030
Keywords : Flame ionization detector * Gas chromatography * Liquid chromatography * Mass spectrometry * Phytocannabinoids
OECD category: Biochemistry and molecular biology
Impact factor: 3.637, year: 2019
Method of publishing: Open access
http://doi.org/10.1007/s00216-019-01760-y
Permanent Link: http://hdl.handle.net/11104/0296953File Download Size Commentary Version Access 2019_Beres_ANALYTICAL AND BIOANALYTICAL CHEMISTRY_3069.pdf 2 1.5 MB Other open-access - 6.0496501 - ÚEB 2019 RIV US eng J - Journal Article
Jorda, Radek - Hendrychová, Denisa - Voller, Jiří - Řezníčková, Eva - Gucký, Tomáš - Kryštof, Vladimír
How Selective Are Pharmacological Inhibitors of Cell-Cycle-Regulating Cyclin-Dependent Kinases?
Journal of Medicinal Chemistry. Roč. 61, č. 20 (2018), s. 9105-9120. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) LO1204; GA ČR GA17-14007S
Institutional support: RVO:61389030
Keywords : small-molecule inhibitors * metastatic breast-cancer * 1st global approval * thermal shift assay * dna-damage response * in-vitro * androgen receptor * cdk inhibitors * highly potent * 2,6,9-trisubstituted purines
OECD category: Oncology
Impact factor: 6.054, year: 2018
Permanent Link: http://hdl.handle.net/11104/0289264File Download Size Commentary Version Access 2018_Jorda_JOURNAL OF MEDICINAL CHEMISTRY_9105.pdf 5 7.3 MB Other open-access - 7.0491930 - ÚEB 2019 RIV NL eng J - Journal Article
Široká, Jitka - Čečková, M. - Urbánek, Lubor - Kryštof, Vladimír - Gucký, Tomáš - Hofman, J. - Strnad, Miroslav - Štaud, F.
LC-MS/MS method for determination of cyclin-dependent kinase inhibitors, BP-14 and BP-20, and its application in pharmacokinetic study in rat.
Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences. Roč. 1089, JUL 1 (2018), s. 24-32. ISSN 1570-0232. E-ISSN 1873-376X
R&D Projects: GA ČR GA17-14007S
Institutional support: RVO:61389030
Keywords : seliciclib r-roscovitine * hepatocellular-carcinoma * metabolism * potent * cdc2 * Cyclin-dependent kinase inhibitor * bp-14 * bp-20 * Pharmacokinetics * Tissue distribution
OECD category: Analytical chemistry
Impact factor: 2.813, year: 2018
Permanent Link: http://hdl.handle.net/11104/0285531File Download Size Commentary Version Access 2018_Siroka_JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES_24.pdf 3 995.1 KB Other open-access - 8.0485773 - ÚEB 2018 RIV US eng J - Journal Article
Krajčovičová, S. - Gucký, Tomáš - Hendrychová, Denisa - Kryštof, Vladimír - Soural, M.
A Stepwise Approach for the Synthesis of Folic Acid Conjugates with Protein Kinase Inhibitors.
Journal of Organic Chemistry. Roč. 82, č. 24 (2017), s. 13530-13541. ISSN 0022-3263. E-ISSN 1520-6904
R&D Projects: GA ČR(CZ) GA15-15264S; GA MŠMT(CZ) LO1304
Institutional support: RVO:61389030
Keywords : CYCLIN-DEPENDENT KINASES * FOLATE RECEPTOR * REGIOSELECTIVE SYNTHESIS
OECD category: Organic chemistry
Impact factor: 4.805, year: 2017
Permanent Link: http://hdl.handle.net/11104/0280716File Download Size Commentary Version Access 2017_Krajcovicova_JOURNAL OF ORGANIC CHEMISTRY_13530.pdf 7 2.7 MB Other open-access - 9.0476276 - ÚEB 2018 RIV GB eng J - Journal Article
Zahajská, Lenka - Nisler, Jaroslav - Voller, Jiří - Gucký, Tomáš - Pospíšil, Tomáš - Spíchal, Lukáš - Strnad, Miroslav
Preparation, characterization and biological activity of C8-substituted cytokinins.
Phytochemistry. Roč. 135, MAR (2017), s. 115-127. ISSN 0031-9422. E-ISSN 1873-3700
Institutional support: RVO:61389030
Keywords : potential purine antagonists * arabidopsis-thaliana * nucleosides * derivatives * thidiazuron * specificity * receptors * kinetin * Organic synthesis * Cytokinin bioassay * AHK3 and CRE1/AHK4 bacterial receptor assay * C8-substituted cytokinin
OECD category: Organic chemistry
Impact factor: 3.186, year: 2017
Permanent Link: http://hdl.handle.net/11104/0272814File Download Size Commentary Version Access 2017_Zahajska_PHYTOCHEMISTRY_115.pdf 3 1 MB Other open-access - 10.0454968 - ÚEB 2016 RIV GB eng J - Journal Article
Řezníčková, Eva - Weitensteiner, S. - Havlíček, Libor - Jorda, Radek - Gucký, Tomáš - Berka, K. - Bazgier, Václav - Zahler, S. - Kryštof, Vladimír - Strnad, Miroslav
Characterization of a Pyrazolo[4,3-d]pyrimidine Inhibitor of Cyclin-dependent Kinases 2 and 5 and Aurora A With Pro-Apoptotic and Anti-Angiogenic Activity In Vitro.
Chemical Biology & Drug Design. Roč. 86, č. 6 (2015), s. 1528-1540. ISSN 1747-0277. E-ISSN 1747-0285
R&D Projects: GA ČR GAP305/12/0783; GA ČR GA14-19590S; GA MŠMT(CZ) LO1204
Institutional support: RVO:61389030
Keywords : angiogenesis * apoptosis * aurora A
Subject RIV: CE - Biochemistry
Impact factor: 2.802, year: 2015
http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=CCC&DestLinkType=FullRecord&UT=000367376800022
Permanent Link: http://hdl.handle.net/11104/0255626File Download Size Commentary Version Access 2015_Reznickova_CHEMICAL BIOLOGY & DRUG DESIGN_1528.pdf 1 2.2 MB Other open-access