Search results
- 1.0389601 - BFÚ 2013 RIV US eng J - Journal Article
Florian, Jakub - Kašpárková, Jana - Farell, N.P. - Brabec, Viktor
Thermodynamic stability and energetics of DNA duplexes containing major intrastrand cross-links of second-generation antitumor dinuclear Pt-II complexes.
Journal of Biological Inorganic Chemistry. Roč. 17, č. 2 (2012), s. 187-196. ISSN 0949-8257. E-ISSN 1432-1327
R&D Projects: GA ČR(CZ) GD301/09/H004; GA ČR(CZ) GAP301/10/0598; GA MŠMT(CZ) ME10066
Institutional support: RVO:68081707
Keywords : NUCLEOTIDE EXCISION-REPAIR * PLATINUM ANTICANCER DRUGS * GROUP DOMAIN PROTEINS
Subject RIV: BO - Biophysics
Impact factor: 3.353, year: 2012
Permanent Link: http://hdl.handle.net/11104/0218466 - 2.0386048 - BFÚ 2013 RIV DE eng J - Journal Article
Muchová, T. - Quintal, S.M. - Farrell, N.P. - Brabec, Viktor - Kašpárková, J.
Antitumor bifunctional dinuclear PtII complex BBR3535 forms interduplex DNA cross-links under molecular crowding conditions.
Journal of Biological Inorganic Chemistry. Roč. 17, č. 2 (2012), s. 239-245. ISSN 0949-8257. E-ISSN 1432-1327
R&D Projects: GA MŠMT(CZ) ME10066
Institutional research plan: CEZ:AV0Z50040702
Keywords : antitumor platinum * DNA * calorimetry
Subject RIV: BO - Biophysics
Impact factor: 3.353, year: 2012
Permanent Link: http://hdl.handle.net/11104/0220148 - 3.0373238 - BFÚ 2012 RIV US eng J - Journal Article
Olivová, R. - Kašpárková, Jana - Vrána, Oldřich - Vojtíšková, Marie - Suchánková, T. - Nováková, Olga - He, W. - Guo, Z. - Brabec, Viktor
Unique DNA binding mode of antitumor trinuclear tridentate platinum(II) compound.
Molecular Pharmaceutics. Roč. 8, č. 6 (2011), s. 2368-2378. ISSN 1543-8384. E-ISSN 1543-8392
R&D Projects: GA MŠMT(CZ) ME10066
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : platinum * antitumor * DNA
Subject RIV: BO - Biophysics
Impact factor: 4.782, year: 2011
Permanent Link: http://hdl.handle.net/11104/0006877 - 4.0366089 - BFÚ 2012 RIV DE eng J - Journal Article
Malina, Jaroslav - Farrell, N.P. - Brabec, Viktor
DNA interstrand cross-links of an antitumor trinuclear platinum(II) complex: Thermodynamic analysis and chemical probing.
Chemistry-An Asian Journal. Roč. 6, č. 6 (2011), s. 1566-1574. ISSN 1861-4728. E-ISSN 1861-471X
R&D Projects: GA MŠMT(CZ) LC06030; GA MŠMT(CZ) ME10066; GA AV ČR(CZ) IAA400040803; GA ČR(CZ) GAP301/10/0598; GA ČR(CZ) GAP205/11/0856
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : calorimetry * DNA damage * interstrand cross-link
Subject RIV: BO - Biophysics
Impact factor: 4.500, year: 2011
Permanent Link: http://hdl.handle.net/11104/0201180 - 5.0358135 - BFÚ 2011 RIV GB eng J - Journal Article
Malina, Jaroslav - Kašpárková, J. - Farrell, N.P. - Brabec, Viktor
Walking of antitumor bifunctional trinuclear PtII complex on double-helical DNA.
Nucleic Acids Research. Roč. 39, č. 2 (2011), s. 720-728. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA MŠMT(CZ) ME08017; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) IAA400040803; GA MŠMT(CZ) ME10066
Grant - others:GA MŠk(CZ) LC06030; GA MŠk(CZ) OC09018; GA AV ČR(CZ) KAN200200651
Program: LC; KA
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : BBR3464 * DNA * cross-link
Subject RIV: BO - Biophysics
Impact factor: 8.026, year: 2011
Permanent Link: http://hdl.handle.net/11104/0196242 - 6.0353781 - BFÚ 2011 RIV US eng J - Journal Article
Kostrhunová, Hana - Vrána, Oldřich - Suchánková, T. - Gibson, D. - Kašpárková, Jana - Brabec, Viktor
Different features of the DNA binding mode of antitumor cis-amminedichlorido(cyclohexylamine)platinum(II) (JM118) and cisplatin in vitro.
Chemical Research in Toxicology. Roč. 23, č. 11 (2010), s. 1833-1842. ISSN 0893-228X. E-ISSN 1520-5010
R&D Projects: GA MŠMT(CZ) ME08017; GA MŠMT(CZ) ME10066; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) IAA400040803; GA ČR(CZ) GAP301/10/0598
Grant - others:GA MŠk(CZ) LC06030; GA MŠk(CZ) OC09018; GA AV ČR(CZ) KAN200200651
Program: LC; KA
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : JM118 * DNA bending * DNA-protein cross-linking
Subject RIV: BO - Biophysics
Impact factor: 4.148, year: 2010
Permanent Link: http://hdl.handle.net/11104/0192929 - 7.0353777 - BFÚ 2011 RIV US eng J - Journal Article
Kostrhunová, Hana - Kašpárková, Jana - Gibson, D. - Brabec, Viktor
Studies on cellular accumulation of satraplatin and its major metabolite JM118 and their interactions with glutathione.
Molecular Pharmaceutics. Roč. 7, č. 6 (2010), s. 2093-2102. ISSN 1543-8384. E-ISSN 1543-8392
R&D Projects: GA MŠMT(CZ) ME08017; GA MŠMT(CZ) ME10066; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) IAA400040803; GA ČR(CZ) GAP301/10/0598
Grant - others:GA MŠk(CZ) LC06030; GA AV ČR(CZ) KAN200200651
Program: LC; KA
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : JM118 * cellular accumulation * glutathione
Subject RIV: BO - Biophysics
Impact factor: 5.400, year: 2010
Permanent Link: http://hdl.handle.net/11104/0006241 - 8.0347441 - BFÚ 2011 RIV US eng J - Journal Article
Zerzánková, Lenka - Kostrhunová, Hana - Vojtíšková, Marie - Nováková, Olga - Suchánková, T. - Lin, M. - Guo, Z. - Kašpárková, Jana - Brabec, Viktor
Mechanistic insights into antitumor effects of new dinuclear cis PtII complexes containing aromatic linkers.
Biochemical Pharmacology. Roč. 80, č. 3 (2010), s. 344-351. ISSN 0006-2952. E-ISSN 1873-2968
R&D Projects: GA MŠMT(CZ) LC06030; GA MŠMT(CZ) ME08017; GA MŠMT(CZ) ME10066; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) IAA400040803; GA ČR(CZ) GD301/09/H004; GA ČR(CZ) GAP301/10/0598
Grant - others:GA MŠk(CZ) OC09018; GA AV ČR(CZ) KAN200200651
Program: KA
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : DNA * platinum * cancer
Subject RIV: BO - Biophysics
Impact factor: 4.889, year: 2010
Permanent Link: http://hdl.handle.net/11104/0188216 - 9.0343993 - BFÚ 2011 RIV DE eng J - Journal Article
Nováková, Olga - Malina, Jaroslav - Suchánková, T. - Kašpárková, Jana - Bugarcic, T. - Sadler, P.J. - Brabec, Viktor
Energetics, conformation, and recognition of DNA duplexes modified by monodentate Ru(II) complexes containing terphenyl arenes.
Chemistry - A European Journal. Roč. 16, č. 19 (2010), s. 5744-5754. ISSN 0947-6539. E-ISSN 1521-3765
R&D Projects: GA ČR(CZ) GD301/09/H004; GA MŠMT(CZ) LC06030; GA MŠMT(CZ) ME08017; GA MŠMT(CZ) ME10066; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) KAN200200651
Grant - others:GA MŠk(CZ) OC09018
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : calorimetry * ruthenium * DNA recognition
Subject RIV: BO - Biophysics
Impact factor: 5.476, year: 2010
Permanent Link: http://hdl.handle.net/11104/0186335