Search results
- 1.0421996 - ÚOCHB 2014 BR eng A - Abstract
Kašička, Václav - Šolínová, Veronika - Sázelová, Petra - Mikysková, Hana - Koval, Dušan - Holý, Antonín
Enantiopurity analysis of anti-AIDS drugs and related acyclic nucleoside phosphonates-based antivirotics by capillary electrophoresis.
LACE 2013. 19th Latin-American Symposium on Biotechnology, Biomedical, Biopharmaceutical, and Industrial Applications of Capillary Electrophoresis and Microchip Technology. Alphaville: AlphaGraphics, 2013 - (Guzman, N.; Tavares, M.). s. 32-32
[LACE 2013. Latin-American Symposium on Biotechnology, Biomedical, Biopharmaceutical, and Industrial Applications of Capillary Electrophoresis and Microchip Technology /19./. 29.11.2013-03.12.2013, Lima]
R&D Projects: GA ČR(CZ) GAP206/12/0453; GA ČR(CZ) GA13-17224S; GA MŠMT(CZ) ME10040; GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * capillary electrophoresis * chiral analysis
Subject RIV: CB - Analytical Chemistry, Separation
Permanent Link: http://hdl.handle.net/11104/0228279 - 2.0399039 - ÚOCHB 2014 US eng A - Abstract
Williams, M. M. - Kashemirov, B. A. - Krečmerová, Marcela - Tichý, Tomáš - Prichard, M. N. - Drach, J. C. - Hilfinger, J. M. - McKenna, Ch. E.
Novel 2,4-diaminopyrimidine Nucleoside Phosphonate Antiviral Prodrugs.
26th International Conference on Antiviral Research (ICAR). San Francisco: International Society for Antiviral Research (ISAR), 2013. s. 81-82.
[International Conference on Antiviral Research /26./. 11.05.2013-15.05.2013, San Francisco]
R&D Projects: GA MŠMT(CZ) ME10040
Grant - others:AV ČR(CZ) M200551201
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonate * antivirals * tyrosine
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0226442 - 3.0384386 - ÚOCHB 2013 US eng A - Abstract
Krečmerová, Marcela - Blažek, Jiří - Tichý, Tomáš - Andrei, G. - Balzarini, J. - Snoeck, R.
New Approaches in Development of Prodrugs of Antivirally Active Acyclic Nucleoside Phosphonates.
2nd Antivirals Congress. From Bench to Bedside. Cambridge: Elsevier, 2012.
[Antivirals Congress. From Bench to Bedside /2./. 11.11.2012-13.11.2012, Cambridge]
R&D Projects: GA MŠMT(CZ) ME10040
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonate * prodrug * amidate * POM
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0214060 - 4.0367761 - ÚOCHB 2012 US eng A - Abstract
Pomeisl, Karel
Syntheses of 1-[2-(phosphonomethoxy)alkyl)thymine monophosphates as potential inhibitors of human thymidine phosphorylase.
43rd Western Regional Meeting. Pasadena: ACS, 2011. RM WRM15-RM WRM15.
[Western Regional Meeting /43./. 10.11.2011-12.11.2011, Pasadena]
R&D Projects: GA MŠMT 1M0508; GA MŠMT(CZ) ME10040
Institutional research plan: CEZ:AV0Z40550506
Keywords : thymidine phosphorylase * phosphorylation * acyclic nucleoside phosphonates * pyrimidines
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0202317 - 5.0367758 - ÚOCHB 2012 US eng A - Abstract
Tichý, Tomáš - Pomeisl, Karel - Krečmerová, Marcela - McKenna, C.
Synthesis of tyrosine side chain-linked prodrugs of PMEG and cpr-PMEDAP.
43rd Western Regional Meeting. Pasadena: ACS, 2011. RM WRM16-RM WRM16.
[Western Regional Meeting /43./. 10.11.2011-12.11.2011, Pasadena]
R&D Projects: GA MŠMT 1M0508; GA MŠMT(CZ) ME10040
Institutional research plan: CEZ:AV0Z40550506
Keywords : prodrugs * tyrosine * acyclic nucleoside phosphonate * antiproliferative effects
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0202314 - 6.0360746 - ÚOCHB 2012 NL eng A - Abstract
McKenna, Ch. E. - Kashemirov, B. A. - Zakharova, V. M. - Krylov, I. S. - Williams, M. - Krečmerová, Marcela - Drach, J. C. - Hilfinger, J. M.
Amido tyrosine esters: a promising new approach to antiviral nucleoside phosphonate prodrugs.
Antiviral Research. Elsevier. Roč. 90, - (2011), A23-A24. ISSN 0166-3542. E-ISSN 1872-9096.
[International Conference on Antiviral Research (ICAR) /24./. 08.05.2011-11.05.2011, Sofia]
R&D Projects: GA MŠMT(CZ) ME10040
Institutional research plan: CEZ:AV0Z40550506
Keywords : antiviral activity * ANP * phosphonates * oral bioavailability * tyrosine * ester prodrugs
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0198226 - 7.0352079 - ÚOCHB 2011 US eng A - Abstract
Pomeisl, Karel - Fanfrlík, Jindřich - Přenosil, Ondřej - Votruba, Ivan - Horská, Květoslava - Pohl, Radek - Tichý, Tomáš - Krečmerová, Marcela
Docking Study of Pyrimidine Acyclic Nucleoside Phosphonates in Interaction with Human Thymidine Phosphorylase as a Support for Potential Explanation of their Inhibitory Activity.
Frontiers in the Simulation of Macromolecules. A Symposium in Honor of Professor Arieh Warshel on the Event of His 70th Birtday. Los Angeles: University of Southern California, 2010. s. 45-45.
[Frontiers in the Simulation of Macromolecules. A Symposium in Honor of Professor Arieh Warshel on the Event of His 70th Birtday. 12.11.2010-14.11.2010, Los Angeles]
R&D Projects: GA MŠMT(CZ) ME10040
Institutional research plan: CEZ:AV0Z40550506
Keywords : thymidine phosphorylase * phosphates * acyclic nucleoside phosphonates * docking study
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0191670