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- 1.0441230 - ÚMG 2015 RIV US eng J - Journal Article
Hubáčková, Soňa - Krejčíková, Kateřina - Bártek, Jiří - Hodný, Zdeněk
IL1-and TGF beta-Nox4 signaling, oxidative stress and DNA damage response are shared features of replicative, oncogene-induced, and drug-induced paracrine 'Bystander senescence'.
Aging. Roč. 4, č. 12 (2012), 932-951. ISSN 1945-4589
R&D Projects: GA ČR GA204/08/1418; GA ČR GAP301/10/1525
Institutional support: RVO:68378050
Keywords : senescence-associated secretome * DNA damage response * cytokines * JAK/STAT3 * TGF beta * NF kappa B * IL6 * IL beta * Nox4 * autocrine and paracrine signaling * tumor
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 4.696, year: 2012
Permanent Link: http://hdl.handle.net/11104/0244280File Download Size Commentary Version Access 0441230.pdf 5 3 MB Publisher’s postprint require - 2.0423172 - ÚMG 2014 RIV US eng J - Journal Article
Kleiblová, P. - Shaltiel, I.A. - Benada, Jan - Ševčík, J. - Pecháčková, Soňa - Pohlreich, P. - Voest, E.E. - Dundr, P. - Bártek, Jiří - Kleibl, Z. - Medema, R.H. - Macůrek, Libor
Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint.
Journal of Cell Biology. Roč. 201, č. 4 (2013), s. 511-521. ISSN 0021-9525. E-ISSN 1540-8140
R&D Projects: GA ČR GAP301/10/1525; GA ČR GAP305/12/2485; GA ČR GA13-18392S
Grant - others:GA MZd(CZ) NT13343; EK(XE) 223575; EK(XE) ED0030/01/01
Institutional support: RVO:68378050
Keywords : DNA damage * cell cycle * cancer
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 9.786, year: 2013
Permanent Link: http://hdl.handle.net/11104/0229361File Download Size Commentary Version Access 0423172.pdf 10 4.1 MB Publisher’s postprint require 0423172.pdf 6 3.2 MB Publisher’s postprint require - 3.0394847 - BFÚ 2014 RIV US eng J - Journal Article
Ševčík, J. - Falk, Martin - Macůrek, Libor - Kleiblová, P. (ed.) - Lhota, F. (ed.) - Hojný, J. - Štefančíková, Lenka - Janatová, M. - Bártek, Jiří (ed.) - Stříbrná, J. - Hodný, Zdeněk - Ježková, L. - Pohlreich, P. - Kleibl, Z.
Expression of human BRCA1 Delta 17-19 alternative splicing variant with a truncated BRCT domain in MCF-7 cells results in impaired assembly of DNA repair complexes and aberrant DNA damage response.
Cellular Signalling. Roč. 25, č. 5 (2013), s. 1186-1193. ISSN 0898-6568. E-ISSN 1873-3913
R&D Projects: GA ČR(CZ) GAP301/10/1525; GA ČR(CZ) GBP302/12/G157
Grant - others:GA ČR(CZ) GAP301/12/1850
Program: GA
Institutional support: RVO:68081707 ; RVO:68378050
Keywords : STRAND BREAK REPAIR * INDUCED NUCLEAR FOCI * OVARIAN-CANCER
Subject RIV: BO - Biophysics; EB - Genetics ; Molecular Biology (UMG-J)
Impact factor: 4.471, year: 2013
Permanent Link: http://hdl.handle.net/11104/0223008 - 4.0390254 - ÚMG 2013 RIV US eng J - Journal Article
Macůrek, Libor - Benada, Jan - Müllers, E. - Halim, V.A. - Krejčíková, Kateřina - Burdová, Kamila - Pecháčková, Soňa - Hodný, Zdeněk - Lindqvist, A. - Medema, R.H. - Bártek, Jiří
Downregulation of Wip1 phosphatase modulates the cellular threshold of DNA damage signaling in mitosis.
Cell Cycle. Roč. 12, č. 2 (2013), s. 251-262. ISSN 1538-4101. E-ISSN 1551-4005
R&D Projects: GA ČR GPP305/10/P420; GA ČR GAP301/10/1525
Grant - others:Netherlands Genomic Initiative of NWO(NL) CGC; EK(XE) 259893
Institutional support: RVO:68378050
Keywords : DNA damage response * Wip1 phosphatase * cell cycle * mitotic progression * γH2AX
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 5.006, year: 2013
Permanent Link: http://hdl.handle.net/11104/0219409File Download Size Commentary Version Access 0390254.pdf 4 2.6 MB Publisher’s postprint require - 5.0387884 - ÚMG 2013 RIV US eng J - Journal Article
Moudrý, Pavel - Lukas, C. - Macůrek, Libor - Hanzlíková, Hana - Hodný, Zdeněk - Lukas, J. - Bártek, Jiří
Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage.
Cell Cycle. Roč. 11, č. 8 (2012), s. 1573-1582. ISSN 1538-4101. E-ISSN 1551-4005
R&D Projects: GA ČR GA301/08/0353; GA ČR GAP301/10/1525
Grant - others:7.RP EU(XE) CZ.1.05/2.1.00/01.0030
Institutional research plan: CEZ:AV0Z50520514
Keywords : 53BP1 * DNA damage response * UBA1 * UBA6 * ubiquitylation
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 5.321, year: 2012
Permanent Link: http://hdl.handle.net/11104/0218364 - 6.0387882 - ÚMG 2013 RIV GB eng J - Journal Article
Moudrý, Pavel - Lukas, C. - Macůrek, Libor - Neumann, B. - Heriche, J.K. - Pepperkok, R. - Ellenberg, J. - Hodný, Zdeněk - Lukas, J. - Bártek, Jiří
Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1.
Cell Death and Differentiation. Roč. 19, č. 5 (2012), s. 798-807. ISSN 1350-9047. E-ISSN 1476-5403
R&D Projects: GA ČR GA301/08/0353; GA ČR GAP301/10/1525; GA ČR GPP305/10/P420
Grant - others:7.RP EU(XE) CZ.1.05/2.1.00/01.0030
Institutional research plan: CEZ:AV0Z50520514
Keywords : DNA damage response * NUP153 * 53BP1 nuclear import
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 8.371, year: 2012
Permanent Link: http://hdl.handle.net/11104/0218366File Download Size Commentary Version Access 0387882.pdf 6 758.7 KB Publisher’s postprint require - 7.0387880 - ÚMG 2013 RIV GB eng J - Journal Article
Medema, R.H. - Macůrek, Libor
Checkpoint control and cancer.
Oncogene. Roč. 31, č. 21 (2012), s. 2601-2613. ISSN 0950-9232. E-ISSN 1476-5594
R&D Projects: GA ČR GAP301/10/1525; GA ČR GPP305/10/P420
Institutional support: RVO:68378050
Keywords : DNA damage * checkpoint control * anticancer strategies
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 7.357, year: 2012
Permanent Link: http://hdl.handle.net/11104/0218383 - 8.0372322 - ÚMG 2012 RIV GB eng J - Journal Article
Tanenbaum, M.E. - Macůrek, Libor - van der Vaart, B. - Galli, M. - Akhmanova, A. - Medema, R.H.
A complex of Kif18b and MCAK promotes microtubule depolymerization and is negatively regulated by aurora kinases.
Current Biology. Roč. 21, č. 16 (2011), s. 1356-1365. ISSN 0960-9822. E-ISSN 1879-0445
R&D Projects: GA ČR GAP301/10/1525; GA ČR GPP305/10/P420
Institutional research plan: CEZ:AV0Z50520514
Keywords : checkpoint * DNA damage * cancer
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 9.647, year: 2011
Permanent Link: http://hdl.handle.net/11104/0205669 - 9.0372311 - ÚMG 2012 RIV GB eng J - Journal Article
Medema, R.H. - Macůrek, Libor
Checkpoint recovery in cells: how a molecular understanding can help in the fight against cancer.
F1000 biology reports. Roč. 3, - (2011), e10. ISSN 1757-594X
R&D Projects: GA ČR GAP301/10/1525; GA ČR GPP305/10/P420
Institutional research plan: CEZ:AV0Z50520514
Keywords : checkpoint * DNA damage * cancer
Subject RIV: EB - Genetics ; Molecular Biology
Permanent Link: http://hdl.handle.net/11104/0205659