Search results
- 1.0552667 - ÚOCHB 2022 CZ eng A - Abstract
Strmeň, Timotej - Chalupská, Dominika - Otava, Tomáš - Krafčíková, Petra - Nencka, Radim - Bouřa, Evžen - Mertlíková-Kaiserová, Helena
High Throughput Mass Spectrometry in Determination of Inhibitors for SARS-COV2 Methyltransferase.
Prague Meeting on Historical Perspectives of Mass Spectrometry, Book of Abstracts. Praha: Ústav organické chemie a biochemie AV ČR, v. v. i., 2021 - (Hoskovec, M.; Cvačka, J.). s. 59. ISBN 978-80-86241-66-1.
[Prague Meeting on Historical Perspectives of Mass Spectrometry. 13.10.2021-14.10.2021, Praha]
Institutional support: RVO:61388963
Keywords : mass spectrometry
OECD category: Analytical chemistry
http://ms-prague2021.uochb.cas.cz/assets/pdf/BoA_final.pdf
Permanent Link: http://hdl.handle.net/11104/0327785 - 2.0548469 - ÚOCHB 2022 CZ eng A - Abstract
Hadzima, Martin - Houštecká, Radka - Pallová, Lenka - Hánová, Iva - Fanfrlík, Jindřich - Brynda, Jiří - Lepšík, Martin - Mertlíková-Kaiserová, Helena - Horn, Martin - Mareš, Michael - Majer, Pavel
Design, Synthesis and Activity of Biomimetic Macrocyclic Inhibitors of Human Cathepsin D.
Liblice 2021. 55th Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2021. s. 112.
[Liblice 2021. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /55./. 03.11.2021-06.11.2021, Špindlerův Mlýn]
Institutional support: RVO:61388963
Keywords : inhibitor * cathepsin * macrocycles * peptides * statine * synthesis
OECD category: Medicinal chemistry
Permanent Link: http://hdl.handle.net/11104/0324491 - 3.0518499 - ÚOCHB 2020 TH eng A - Abstract
Břehová, Petra - Šmídková, Markéta - Skácel, Jan - Dračínský, Martin - Mertlíková-Kaiserová, Helena - Velasquez, M. P. S. - Watts, W. J. - Janeba, Zlatko
Synthesis of acyclic nucleoside phosphonates derived from 2-aminothiazoles and their evaluation as inhibitors of bacterial and human adenylate cyclases.
20th Tetrahedron Symposium. Bangkok: Elsevier, 2019. P1.005, „P1004“.
[Tetrahedron Symposium /20./. 18.06.2019-21.06.2019, Bangkok]
Institutional support: RVO:61388963
Keywords : nucleoside analogues * adenylate cyclases * aminothiazoles
OECD category: Organic chemistry
Permanent Link: http://hdl.handle.net/11104/0303890 - 4.0518498 - ÚOCHB 2020 TH eng A - Abstract
Česnek, Michal - Šafránek, Michal - Skácel, Jan - Dračínský, Martin - Mertlíková-Kaiserová, Helena - Velasquez, M. P. S. - Watts, W. J. - Janeba, Zlatko
Synthesis of 5-[2-(phosphonomethoxy)ethyl] (PME) derivatives of 4-substituted 2-aminothiazoles as potential inhibitors of bacterial and human adenylate cyclases.
20th Tetrahedron Symposium. Bangkok: Elsevier, 2019. P1.005, „P1005“.
[Tetrahedron Symposium /20./. 18.06.2019-21.06.2019, Bangkok]
Institutional support: RVO:61388963
Keywords : adenylate cyclases * aminothiazoles
OECD category: Organic chemistry
Permanent Link: http://hdl.handle.net/11104/0303886 - 5.0506263 - ÚOCHB 2020 CZ eng A - Abstract
Skácel, Jan - Baszczyňski, Ondřej - Mertlíková-Kaiserová, Helena - Tloušťová, Eva - Pachl, Petr - Maloy Řezáčová, Pavlína - Snášel, Jan - Pichová, Iva - Janeba, Zlatko
Development of purine nucleoside phosphorylase inhibitors as potential anticancer therapeutics.
Czech Chemical Society Symposium Series. Roč. 17, č. 1 (2019), s. 34. ISSN 2336-7202.
[Interdisciplinary Meeting of Young Researchers and Students in the Field of Chemistry, Biochemistry, Molecular Biology, and Biomaterials /19./. 20.05.2019-23.05.2019, Milovy]
R&D Projects: GA TA ČR(CZ) TN01000013
Institutional support: RVO:61388963
Keywords : PNP * anticancer therapeutics
OECD category: Organic chemistry
Permanent Link: http://hdl.handle.net/11104/0297752 - 6.0485188 - ÚOCHB 2018 HR eng A - Abstract
Nencka, Radim - Mejdrová, Ivana - Chalupská, Dominika - Plačková, Pavla - Müller, C. - Šála, Michal - Procházková, Eliška - Bäumlová, Adriana - Dejmek, Milan - Strunin, Dmytro - Weber, Jan - Lee, G. - Mertlíková-Kaiserová, Helena - Ziebuhr, J. - Birkuš, G. - Bouřa, Evžen
Rational design of PI4KB inhibitors as potential broad-spectrum antiviral agents.
10th Joint Meeting on Medicinal Chemistry. Zagreb: Croatian Chemical Society, 2017 - (Basarić, N.; Namjesnik, D.; Perković, I.; Stepanić, V.). s. 47. ISBN 978-953-55232-8-4.
[Joint Meeting on Medicinal Chemistry /10./. 25.06.2017-28.06.2017, Dubrovnik]
R&D Projects: GA ČR GA15-09310S
Institutional support: RVO:61388963
Keywords : PI4K * enzyme inhibitor * antiviral
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0280376 - 7.0481195 - ÚOCHB 2018 CZ eng A - Abstract
Česnek, Michal - Dračínský, Martin - Šmídková, Markéta - Mertlíková-Kaiserová, Helena - Velasquez, M. P. S. - Watts, V. J. - Janeba, Zlatko
Synthesis and evaluation of novel acyclic nucleoside phosphonates with unnatural nucleobases as potent inhibitors of Bordetella pertussis adenylate cyclase toxin.
SCNAC 2017. 17th Symposium on Chemistry of Nucleic Acid Components. Praha: Confis Conference, 2017. s. 128.
[SCNAC 2017. Symposium on Chemistry of Nucleic Acid Components /17./. 04.06.2017-09.06.2017, Český Krumlov]
R&D Projects: GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates (ANPs) * adenylate cyclase toxin (ACT) * Bordetella pertussis
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0276795 - 8.0481189 - ÚOCHB 2018 CZ eng A - Abstract
Břehová, Petra - Šmídková, Markéta - Skácel, Jan - Dračínský, Martin - Mertlíková-Kaiserová, Helena - Velasquez, M. P. S. - Watts, V. J. - Janeba, Zlatko
Synthesis of acyclic nucleoside phosphonates with unnatural heterocyclic bases bearing aryl substituents and their inhibitory activity towards bacterial and human adenylate cyclases.
SCNAC 2017. 17th Symposium on Chemistry of Nucleic Acid Components. Praha: Confis Conference, 2017. s. 125.
[SCNAC 2017. Symposium on Chemistry of Nucleic Acid Components /17./. 04.06.2017-09.06.2017, Český Krumlov]
R&D Projects: GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates (ANPs) * adenylate cyclase toxin (ACT) * Bordetella pertussis
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0276789 - 9.0465007 - ÚOCHB 2017 NL eng A - Abstract
Frydrych, Jan - Dračínský, Martin - Gnanasekaran, Ramachandran - Lepšík, Martin - Šmídková, Markéta - Tloušťová, Eva - Mertlíková-Kaiserová, Helena - Janeba, Zlatko
Novel adenine acyclic nucleoside phosphonates and their derivatives as potent inhibitors of bacterial adenylate cyclases.
ECHC 2016. 27th European Colloquium on Heterocyclic Chemistry. Amsterdam: -, 2016.
[ECHC 2016. European Colloquium on Heterocyclic Chemistry /27./. 03.07.2016-06.07.2016, Amsterdam]
R&D Projects: GA MV VG20102015046; GA ČR(CZ) GBP208/12/G016; GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : acyclic nuceloside phosphonates * bacterial adenylate cyclases
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0263730 - 10.0464963 - ÚOCHB 2017 ES eng A - Abstract
Břehová, Petra - Šmídková, Markéta - Mertlíková-Kaiserová, Helena - Skácel, Jan - Dračínský, Martin - Janeba, Zlatko
Synthesis of acyclic nucleoside phosphonates bearing aryl substituent at the acyclic linker as potential inhibitors of adenylate cyclase toxin from Bordetella pertussis.
17th Tetrahedron Symposium. Challenges in Biological, Bioorganic, Organic and Medicinal Chemistry. Sitges: Elsevier, 2016.
[Tetrahedron Symposium. Challenges in Biological, Bioorganic, Organic and Medicinal Chemistry /17./. 28.06.2016-01.07.2016, Sitges]
R&D Projects: GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates (ANPs) * adenylate cyclase toxin (ACT) * Bordetella pertussis
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0263697