Search results
- 1.0566142 - ÚMG 2023 RIV CH eng J - Journal Article
Chrienová, Z. - Ryšánek, David - Oleksak, P. - Starý, D. - Bajda, M. - Reiniš, Milan - Mikyšková, Romana - Novotný, Ondřej - Andrýs, R. - Skarka, A. - Vašicová, Pavla - Novák, Josef - Vališ, M. - Kuca, K. - Hodný, Zdeněk - Nepovimova, E.
Discovery of small molecule mechanistic target of rapamycin inhibitors as anti-aging and anti-cancer therapeutics.
Frontiers in Aging Neuroscience. Roč. 14, December (2022), č. článku 1048260. ISSN 1663-4365. E-ISSN 1663-4365
R&D Projects: GA ČR GA20-22037S
Institutional support: RVO:68378050
Keywords : aging * cancer * mTOR * anti-aging therapy * SASP phenotype
OECD category: Neurosciences (including psychophysiology
Impact factor: 4.8, year: 2022
Method of publishing: Open access
https://www.frontiersin.org/articles/10.3389/fnagi.2022.1048260/full
Permanent Link: https://hdl.handle.net/11104/0337586 - 2.0544878 - ÚMG 2022 RIV NZ eng J - Journal Article
Salajková, Šárka - Havel, Filip - Šrámek, Michal - Novotný, Filip - Malinak, D. - Doležal, R. - Prchal, L. - Benková, M. - Soukup, O. - Musílek, K. - Kuca, K. - Bártek, Jiří - Proska, J. - Žárská, Monika - Hodný, Zdeněk
The Effect of Chemical Structure of OEG Ligand Shells with Quaternary Ammonium Moiety on the Colloidal Stabilization, Cellular Uptake and Photothermal Stability of Gold Nanorods.
International Journal of Nanomedicine. Roč. 16, May (2021), s. 3407-3427. E-ISSN 1178-2013
R&D Projects: GA ČR GA16-13967S; GA MZd NV19-08-00523; GA MŠMT(CZ) LM2015062; GA MŠMT(CZ) LM2015062; GA MŠMT(CZ) EF16_013/0001775
Institutional support: RVO:68378050
Keywords : gold nanorods * quaternary ammonium salts * oligoethylene glycol * cellular uptake * photothermal stability
OECD category: Pharmacology and pharmacy
Impact factor: 7.033, year: 2021
Method of publishing: Open access
https://www.dovepress.com/the-effect-of-chemical-structure-of-oeg-ligand-shells-with-quaternary--peer-reviewed-fulltext-article-IJN
Permanent Link: http://hdl.handle.net/11104/0321676 - 3.0525589 - ÚMG 2021 RIV CH eng J - Journal Article
Salajková, Šárka - Benková, M. - Marek, J. - Sleha, R. - Prchal, L. - Malinak, D. - Doležal, R. - Sepcic, K. - Gunde-Cimerman, N. - Kuca, K. - Soukup, O.
Wide-Antimicrobial Spectrum of Picolinium Salts.
Molecules. Roč. 25, č. 9 (2020), č. článku 2254. E-ISSN 1420-3049
Institutional support: RVO:68378050
Keywords : picolinium salts * quaternary ammonium compounds * surfactant * critical micellar concentration * antimicrobial activity * cytotoxicity
OECD category: Pharmacology and pharmacy
Impact factor: 4.412, year: 2020
Method of publishing: Open access
https://www.mdpi.com/1420-3049/25/9/2254
Permanent Link: http://hdl.handle.net/11104/0309702 - 4.0494336 - ÚMG 2019 RIV NL eng J - Journal Article
Žárská, Monika - Šrámek, Michal - Novotný, Filip - Havel, Filip - Babelova, A. - Mrázková, Blanka - Benada, Oldřich - Reiniš, Milan - Štěpánek, Ivan - Musílek, K. - Bártek, Jiří - Ursinyova, M. - Novák, Ondřej - Dzijak, Rastislav - Kuca, K. - Proska, J. - Hodný, Zdeněk
Biological safety and tissue distribution of (16-mercaptohexadecyl) trimethylammonium bromide-modified cationic gold nanorods.
Biomaterials. Roč. 154, February (2018), s. 275-290. ISSN 0142-9612. E-ISSN 1878-5905
R&D Projects: GA ČR GA16-13967S; GA MŠMT(CZ) LO1509; GA MŠMT(CZ) LM2015062; GA MŠMT LO1419
Institutional support: RVO:68378050 ; RVO:61388971 ; RVO:68378041
Keywords : Genotoxicity * Autophagy * Lysosomal stress * Spleen * Thrombocytes * Plasmonic photothermal effect
OECD category: Biomaterials (as related to medical implants, devices, sensors); Biochemical research methods (UEM-P)
Impact factor: 10.273, year: 2018
Permanent Link: http://hdl.handle.net/11104/0287566File Download Size Commentary Version Access 113_Biological_safety_and_tissue_distribution_of.pdf 12 4.6 MB Publisher’s postprint require - 5.0473034 - ÚMG 2017 RIV NL eng J - Journal Article
Andrs, M. - Korábečný, J. - Nepovimova, E. - Jun, D. - Hodný, Zdeněk - Kuca, K.
Small Molecules Targeting Ataxia Telangiectasia and Rad3-Related (ATR) Kinase: An Emerging way to Enhance Existing Cancer Therapy.
Current Cancer Drug Targets. Roč. 16, č. 3 (2016), s. 200-208. ISSN 1568-0096. E-ISSN 1873-5576
Institutional support: RVO:68378050
Keywords : Ataxia telangiectasia and Rad3-related kinase (ATR) * cancer * chemosensitization * DNA damage response * phosphatidylinositol 3-kinase-related protein kinases (PIKK) * radiosensitization * synthetic lethality
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.992, year: 2016
Permanent Link: http://hdl.handle.net/11104/0270203 - 6.0469671 - ÚMG 2017 RIV US eng J - Journal Article
Žárská, Monika - Novotný, Filip - Havel, Filip - Šrámek, Michal - Babelova, A. - Benada, Oldřich - Novotný, M. - Saran, H. - Kuca, K. - Musílek, K. - Hvězdová, Zuzana - Dzijak, Rastislav - Vančurová, Markéta - Krejčíková, Kateřina - Gabajová, Blanka - Hanzlíková, Hana - Kyjacová, Lenka - Bártek, Jiří - Proška, Jan - Hodný, Zdeněk
Two-Step Mechanism of Cellular Uptake of Cationic Gold Nanoparticles Modified by (16-Mercaptohexadecyl)trimethylammonium Bromide.
Bioconjugate Chemistry. Roč. 27, č. 10 (2016), s. 2558-2574. ISSN 1043-1802. E-ISSN 1520-4812
R&D Projects: GA ČR GA16-13967S; GA MŠMT(CZ) LO1509
Grant - others:OPPC(XE) CZ.2.16/3.1.00/24023
Institutional support: RVO:61388971 ; RVO:68378050 ; RVO:61389013
Keywords : mesenchymal stem-cells * mammalian-cells * cancer-cells * photothermal therapy * mediated endocytosis * nonphagocytic cells * optical-properties * light-scattering * senescent cells * dna-damage
Subject RIV: EB - Genetics ; Molecular Biology; EE - Microbiology, Virology (MBU-M); CD - Macromolecular Chemistry (UMCH-V)
Impact factor: 4.818, year: 2016
Permanent Link: http://hdl.handle.net/11104/0269098 - 7.0442572 - ÚMG 2015 RIV NL eng J - Journal Article
Andrs, M. - Kobarecny, J. - Nepovimova, E. - Jun, D. - Hodný, Zdeněk - Moravcová, Simona - Hanzlíková, Hana - Kuca, K.
The Development of Ataxia Telangiectasia Mutated Kinase Inhibitors.
Mini - Reviews in Medicinal Chemistry. Roč. 14, č. 10 (2014), s. 805-811. ISSN 1389-5575. E-ISSN 1875-5607
R&D Projects: GA MŠMT(CZ) CZ.1.07/2.3.00/30.0044
Grant - others:MH CZ - DRO (University Hospital Hradec Kralove(CZ) 00179906
Institutional support: RVO:68378050
Keywords : Ataxia telangiectasia mutated * cancer * chemosensitization * DNA damage response
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.903, year: 2014
Permanent Link: http://hdl.handle.net/11104/0245401 - 8.0442570 - ÚMG 2015 RIV US eng J - Journal Article
Andrs, M. - Kobarecny, J. - Jun, D. - Hodný, Zdeněk - Bártek, Jiří - Kuca, K.
Phosphatidylinositol 3-Kinase (PI3K) and phosphatidylinositol 3-kinase-related kinase (PIKK) inhibitors: importance of the morpholine ring.
Journal of Medicinal Chemistry. Roč. 58, č. 1 (2015), s. 41-71. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) CZ.1.07/2.3.00/30.0044
Grant - others:University Hospital Hradec Kralove(CZ) 00179906; Faculty of Military Health Sciences, University of Defence(CZ) SV/FVZ201402
Institutional support: RVO:68378050
Keywords : DEPENDENT PROTEIN-KINASE * STRAND BREAK REPAIR * SELECTIVE PI3K-BETA INHIBITORS * TELANGIECTASIA MUTATED KINASE
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 5.589, year: 2015
Permanent Link: http://hdl.handle.net/11104/0245400 - 9.0429541 - ÚEB 2015 RIV CH eng J - Journal Article
Kopel, P. - Doležal, Karel - Langer, V. - Jun, D. - Adam, V. - Kuca, K. - Kizek, R.
Trithiocyanurate Complexes of Iron, Manganese and Nickel and Their Anticholinesterase Activity.
Molecules. Roč. 19, č. 4 (2014), s. 4338-4354. E-ISSN 1420-3049
R&D Projects: GA MŠMT(CZ) ED1.1.00/02.0068; GA MŠMT(CZ) LO1204
Institutional support: RVO:61389030
Keywords : crystal structure * trimercaptotriazine * trithiocyanuric acid
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.416, year: 2014
Permanent Link: http://hdl.handle.net/11104/0234632File Download Size Commentary Version Access 2014_Kopel_MOLECULES_4338.pdf 8 2.2 MB Other open-access - 10.0342827 - ÚCHP 2011 RIV US eng J - Journal Article
Musilová, L. - Jun, D. - Paleček, J. - Církva, Vladimír - Musílek, K. - Paar, M. - Hrabinová, M. - Pohanka, M. - Kuca, K.
Novel Nucleophilic Compounds with Oxime Group as Reactivators of Paraoxon-Inhibited Cholinesterases.
Letters in Drug Design & Discovery. Roč. 7, č. 4 (2010), s. 260-264. ISSN 1570-1808. E-ISSN 1875-628X
Grant - others:GA MO(CZ) OVUOFVZ200902
Program: OV
Institutional research plan: CEZ:AV0Z40720504
Keywords : acetylcholinesterase * butyrylcholinesterase * nerve agent
Subject RIV: CC - Organic Chemistry
Impact factor: 0.668, year: 2010
Permanent Link: http://hdl.handle.net/11104/0185451