Search results
- 1.0543910 - FGÚ 2022 RIV GB eng J - Journal Article
Witte, F. - Ruiz-Orera, J. - Mattioli, C. C. - Blachut, S. - Adami, E. - Schulz, J. F. - Schneider-Lunitz, V. - Hummel, O. - Patone, G. - Mücke, M. B. - Šilhavý, Jan - Heinig, M. - Bottolo, L. - Sanchis, D. - Vingron, M. - Chekulaeva, M. - Pravenec, Michal - Hubner, N. - van Heesch, S.
A trans locus causes a ribosomopathy in hypertrophic hearts that affects mRNA translation in a protein length-dependent fashion.
Genome Biology. Roč. 22, č. 1 (2021), č. článku 191. ISSN 1474-760X. E-ISSN 1474-760X
Grant - others:AV ČR(CZ) AP1502
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:67985823
Keywords : genetic variation * trans QTL mapping * translational efficiency * ribosome profiling * cardiac hypertrophy * spontaneously hypertensive rats (SHR)
OECD category: Cardiac and Cardiovascular systems
Impact factor: 18.010, year: 2021
Method of publishing: Open access
https://doi.org/10.1186/s13059-021-02397-w
Permanent Link: http://hdl.handle.net/11104/0321014 - 2.0507837 - FGÚ 2020 RIV GB eng J - Journal Article
Chen, H. - Moreno-Moral, A. - Pesce, F. - Devapragash, N. - Mancini, M. - Heng, E. L. - Rotival, M. - Srivastava, P. K. - Harmston, N. - Shkura, K. - Rackham, O. J. L. - Yu, W.-P. - Sun, X. M. - Tee, N. G. Z. - Tan, E. L. S. - Barton, P. J. R. - Felkin, L. E. - Lara-Pezzi, E. - Angelini, G. - Beltrami, C. - Pravenec, Michal - Schafer, S. - Bottolo, L. - Hubner, N. - Emanueli, C. - Cook, S. A. - Petretto, E.
WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling.
Nature Communications. Roč. 10, Aug 9 (2019), č. článku 3616. E-ISSN 2041-1723
R&D Projects: GA ČR(CZ) GB14-36804G
Grant - others:AV ČR(CZ) AP1502
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:67985823
Keywords : WWP2 * cardiac fibrosis * spontaneously hypertensive rat * SMAD2 signaling
OECD category: Cardiac and Cardiovascular systems
Impact factor: 12.121, year: 2019
Method of publishing: Open access
https://doi.org/10.1038/s41467-019-11551-9
Permanent Link: http://hdl.handle.net/11104/0298799 - 3.0461581 - FGÚ 2017 RIV GB eng J - Journal Article
Wang, M. - Sips, P. - Khin, E. - Rotival, M. - Sun, X. - Ahmed, R. - Widjaja, A. A. - Schafer, S. - Yusoff, P. - Choksi, P. K. - Ko, N. S. J. - Singh, M. K. - Epstein, D. - Guan, Y. - Houštěk, Josef - Mráček, Tomáš - Nůsková, Hana - Mikell, B. - Tan, J. - Pesce, F. - Kolář, František - Bottolo, L. - Mancini, M. - Hubner, N. - Pravenec, Michal - Petretto, E. - MacRae, C. - Cook, S. A.
Wars2 is a determinant of angiogenesis.
Nature Communications. Roč. 7, Jul (2016), s. 12061. E-ISSN 2041-1723
R&D Projects: GA MŠMT(CZ) LL1204; GA ČR(CZ) GB14-36804G; GA MZd(CZ) NT12370
Institutional support: RVO:67985823
Keywords : Wars2 mutant gene * angiogenesis * coronary flow * spontaneously hypertensive rat
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 12.124, year: 2016
Permanent Link: http://hdl.handle.net/11104/0261191 - 4.0392100 - FGÚ 2014 RIV NL eng J - Journal Article
Langley, S. R. - Bottolo, L. - Kuneš, Jaroslav - Zicha, Josef - Zídek, Václav - Hubner, N. - Cook, S.A. - Pravenec, Michal - Aitman, T. J. - Petretto, E.
Systems-level approaches reveal conservation of trans-regulated genes in the rat and genetic determinants of blood pressure in humans.
Cardiovascular Research. Roč. 97, č. 4 (2013), s. 653-665. ISSN 0008-6363. E-ISSN 1755-3245
R&D Projects: GA MŠMT(CZ) LH11049; GA MŠMT(CZ) LL1204; GA MŠMT(CZ) 7E10067
Institutional support: RVO:67985823
Keywords : integrative genomics * expression QTLs * time series analysis * trans-acting regulation * genome-wide association studies
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 5.808, year: 2013
Permanent Link: http://hdl.handle.net/11104/0221065 - 5.0365728 - FGÚ 2012 RIV GB eng J - Journal Article
McDermott-Roe, Ch. - Ye, J. - Ahmed, R. - Sun, X. M. - Serafín, A. - Ware, J. - Bottolo, L. - Muckett, P. - Caňas, X. - Zhang, J. - Rowe, G. C. - Buchan, R. - Lu, H. - Braithwaite, A. - Mancini, M. - Hauton, D. - Martí, R. - García-Arumí, E. - Hubner, N. - Jacob, H. - Serikawa, T. - Zídek, Václav - Papoušek, František - Kolář, František - Cardona, M. - Ruiz-Meana, M. - García-Dorado, D. - Comella, J. X. - Felkin, L. E. - Barton, P. J. R. - Arany, Z. - Pravenec, Michal - Petretto, E. - Sanchis, D. - Cook, S.A.
Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function.
Nature. Roč. 478, č. 7367 (2011), s. 114-118. ISSN 0028-0836. E-ISSN 1476-4687
R&D Projects: GA MŠMT(CZ) 1M0520; GA ČR(CZ) GA301/08/0166
Institutional research plan: CEZ:AV0Z50110509
Keywords : left ventricular hypertrophy * endonuclease G * mitochondrial dysfunction
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 36.280, year: 2011
Permanent Link: http://hdl.handle.net/11104/0200901 - 6.0348257 - FGÚ 2011 RIV GB eng J - Journal Article
Heinig, M. - Petretto, E. - Wallace, C. - Bottolo, L. - Rotival, M. - Lu, H. - Li, Y. - Sarwar, R. - Langley, S. R. - Bauerfeind, A. - Hummel, O. - Lee, Y. A. - Paskas, S. - Rintisch, C. - Saar, K. - Cooper, J. - Buchan, R. - Gray, C. C. - Cyster, J. G. - Erdmann, J. - Hengstenberg, C. - Maouche, S. - Ouwehand, W. H. - Rice, C. M. - Samani, N. J. - Schunkert, H. - Goodall, A. H. - Schulz, H. - Roider, H. G. - Vingron, M. - Blankenberg, S. - Münzel, T. - Zeller, T. - Szymczak, S. - Ziegler, A. - Tiret, L. - Smyth, D. J. - Pravenec, Michal - Aitman, T. J. - Cambien, F. - Clayton, D. - Todd, J. A. - Hubner, N. - Cook, S.A.
A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk.
Nature. Roč. 467, č. 7314 (2010), s. 460-464. ISSN 0028-0836. E-ISSN 1476-4687
R&D Projects: GA MŠMT(CZ) 1M0520; GA ČR GAP301/10/0290
Institutional research plan: CEZ:AV0Z50110509
Keywords : IRF7 driven inflammatory network * Ebi2 * type 1 diabetes
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 36.104, year: 2010
Permanent Link: http://hdl.handle.net/11104/0188834 - 7.0342527 - FGÚ 2011 RIV US eng J - Journal Article
Petretto, E. - Bottolo, L. - Langley, S. R. - Heinig, M. - McDermott-Roe, Ch. - Sarwar, R. - Pravenec, Michal - Hübner, N. - Aitman, T. J. - Cook, S.A. - Richardson, S.
New Insights into the Genetic Control of Gene Expression using a Bayesian Multi-tissue Approach.
PLoS Computational Biology. Roč. 6, č. 4 (2010), e1000737. ISSN 1553-734X. E-ISSN 1553-7358
R&D Projects: GA ČR(CZ) GA301/08/0166; GA MŠMT(CZ) 1M0520; GA ČR GAP301/10/0290
Grant - others:EC(XE) LSHG-CT-2005-019015; Fondation Leducq(FR) 06 CVD 03
Institutional research plan: CEZ:AV0Z50110509
Keywords : expression profiles * Bayesian multi-tissue approach * genetical genomics
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 5.515, year: 2010
Permanent Link: http://hdl.handle.net/11104/0185241