Search results
- 1.0583634 - BFÚ 2024 RIV US eng J - Journal Article
Kostrhunová, Hana - McGhie, B. S. - Marková, Lenka - Nováková, Olga - Kašpárková, Jana - Aldrich-Wright, J.R. - Brabec, Viktor
Platinum(IV) Derivatives of [Pt(1iS/i,2iS/i-diaminocyclohexane)(5,6-dimethyl-1,10-phenanthroline)] with Diclofenac Ligands in the Axial Positions: A New Class of Potent Multi-action Agents Exhibiting Selectivity to Cancer Cells.
Journal of Medicinal Chemistry. Roč. 66, č. 12 (2023), s. 7894-7908. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR(CZ) GA21-27514S
Institutional support: RVO:68081707
Keywords : cyclooxygenase inhibitors * anticancer activity * in-vitro * death * complexes * mechanism * cisplatin * mitochondrial * cytotoxicity
OECD category: Inorganic and nuclear chemistry
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c00269
Permanent Link: https://hdl.handle.net/11104/0351654 - 2.0509895 - BFÚ 2020 RIV US eng J - Journal Article
Kostrhunová, Hana - Zajac, Juraj - Novohradský, Vojtěch - Kašpárková, Jana - Malina, Jaroslav - Aldrich-Wright, J.R. - Petruzzella, V. - Sirota, R. - Gibson, D. - Brabec, Viktor
A Subset of New Platinum Antitumor Agents Kills Cells by a Multimodal Mechanism of Action Also Involving Changes in the Organization of the Microtubule Cytoskeleton.
Journal of Medicinal Chemistry. Roč. 62, č. 10 (2019), s. 5176-5190. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR(CZ) GA18-09502S
Institutional support: RVO:68081707
Keywords : potent cytotoxic agents * deacetylase inhibitor * anticancer activity * pt(iv) derivatives * in-vitro
OECD category: Medicinal chemistry
Impact factor: 6.205, year: 2019
Method of publishing: Limited access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.9b00489
Permanent Link: http://hdl.handle.net/11104/0300487 - 3.0329490 - BFÚ 2010 RIV US eng J - Journal Article
Krause-Heuer, A. M. - Grüner, R. - Kühne, S. - Buczkowska, M. - Wheate, N.J. - Le Pevelen, D.D. - Boag, L.R. - Fisher, D.M. - Kašpárková, Jana - Malina, Jaroslav - Bednarski, P.J. - Brabec, Viktor - Aldrich-Wright, J.R.
Studies of the mechanism of action of platinum(II) complexes with potent cytotoxicity in human cancer cells.
[Studie mechanismu protinádorového působení platnatých komplexů vykazujících silnou cytotoxicitu vůči lidským nádorovým buňkám.]
Journal of Medicinal Chemistry. Roč. 52, č. 17 (2009), s. 5474-5484. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) LC06030; GA MŠMT(CZ) ME08017; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) 1QS500040581; GA AV ČR(CZ) KAN200200651; GA AV ČR(CZ) IAA400040803
Grant - others:GA MŠk(CZ) OC09018
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : platinum * metallointercalator * cytotoxicity
Subject RIV: AQ - Safety, Health Protection, Human - Machine
Impact factor: 4.802, year: 2009
Permanent Link: http://hdl.handle.net/11104/0175510