Search results
- 1.0446237 - BFÚ 2016 RIV US eng J - Journal Article
Novohradský, Vojtěch - Zerzánková, Lenka - Štěpánková, Jana - Vrána, Oldřich - Raveendran, R. - Gibson, D. - Kašpárková, Jana - Brabec, Viktor
New insights into the molecular and epigenetic effects of antitumor Pt(IV)-valproic acid conjugates in human ovarian cancer cells.
Biochemical Pharmacology. Roč. 95, č. 3 (2015), s. 133-144. ISSN 0006-2952. E-ISSN 1873-2968
R&D Projects: GA ČR(CZ) GA14-21053S; GA MŠMT(CZ) LD14019
Institutional support: RVO:68081707
Keywords : HISTONE DEACETYLASE INHIBITORS * MALIGNANT PLEURAL MESOTHELIOMA * VALPROIC ACID
Subject RIV: BO - Biophysics
Impact factor: 5.091, year: 2015
Permanent Link: http://hdl.handle.net/11104/0248226 - 2.0435475 - BFÚ 2015 RIV US eng J - Journal Article
Novohradský, Vojtěch - Zerzánková, Lenka - Štěpánková, Jana - Vrána, Oldřich - Raveendran, R. - Gibson, D. - Kašpárková, Jana - Brabec, Viktor
Antitumor platinum(IV) derivatives of oxaliplatin with axial valproato ligands.
Journal of Inorganic Biochemistry. Roč. 140, NOV2014 (2014), s. 72-79. ISSN 0162-0134. E-ISSN 1873-3344
R&D Projects: GA ČR(CZ) GA14-21053S
Institutional support: RVO:68081707
Keywords : Platinum(IV) prodrugs * Anticancer * Histone deacetylase
Subject RIV: BO - Biophysics
Impact factor: 3.444, year: 2014
Permanent Link: http://hdl.handle.net/11104/0239852 - 3.0435473 - BFÚ 2015 RIV GB eng J - Journal Article
Novohradský, Vojtěch - Zerzánková, Lenka - Štěpánková, Jana - Kisová, Anna - Kostrhunová, Hana - Liu, Z. - Sadler, P. J. - Kašpárková, Jana - Brabec, Viktor
A dual-targeting, apoptosis-inducing organometallic half-sandwich iridium anticancer complex.
Metallomics. Roč. 6, č. 8 (2014), s. 1491-1501. ISSN 1756-5901. E-ISSN 1756-591X
Institutional support: RVO:68081707
Keywords : INDUCED CELL-DEATH * CISPLATIN * DNA
Subject RIV: BO - Biophysics
Impact factor: 3.585, year: 2014
Permanent Link: http://hdl.handle.net/11104/0239339 - 4.0390328 - BFÚ 2013 RIV DE eng J - Journal Article
Terenzi, A. - Ducani, C. - Blanco, V. - Zerzánková, Lenka - Westendorf, A.F. - Peinador, C. - Quintela, J.M. - Bednarski, P.J. - Barone, G. - Hannon, M.J.
DNA Binding Studies and Cytotoxicity of a Dinuclear PtII Diazapyrenium-Based Metallo-supramolecular Rectangular Box.
Chemistry - A European Journal. Roč. 18, č. 35 (2012), s. 10983-10990. ISSN 0947-6539. E-ISSN 1521-3765
Institutional support: RVO:68081707
Keywords : LARGE CALIXARENE DIMERS * SELF-ASSEMBLED HOSTS * CANCER-CELL LINES
Subject RIV: BO - Biophysics
Impact factor: 5.831, year: 2012
Permanent Link: http://hdl.handle.net/11104/0219219 - 5.0381594 - BFÚ 2013 RIV US eng J - Journal Article
Prachařová, J. - Zerzánková, Lenka - Štěpánková, Jana - Nováková, Olga - Farrer, N.J. - Sadler, P.J. - Brabec, Viktor - Kašpárková, Jana
Interactions of DNA with a new platinum(IV) azide dipyridine complex activated by UVA and visible light: Relationship to toxicity in tumor cells.
Chemical Research in Toxicology. Roč. 25, č. 5 (2012), s. 1099-1111. ISSN 0893-228X. E-ISSN 1520-5010
R&D Projects: GA ČR(CZ) GAP301/10/0598; GA ČR(CZ) GD301/09/H004
Institutional research plan: CEZ:AV0Z50040702
Keywords : antitumor platinum * photoactivation * DNA
Subject RIV: BO - Biophysics
Impact factor: 3.667, year: 2012
Permanent Link: http://hdl.handle.net/11104/0212025 - 6.0379149 - BFÚ 2013 RIV US eng J - Journal Article
Brabec, Viktor - Griffith, D.M. - Kisová, Anna - Kostrhunová, Hana - Zerzánková, Lenka - Marmion, C.J. - Kašpárková, Jana
Valuable insight into the anticancer activity of the platinum-histone deacetylase inhibitor conjugate, cis-[Pt(NH3)2malSAHA-2H)].
Molecular Pharmaceutics. Roč. 9, č. 7 (2012), s. 1990-1999. ISSN 1543-8384. E-ISSN 1543-8392
R&D Projects: GA ČR(CZ) GAP301/10/0598; GA ČR(CZ) GPP303/11/P047
Institutional research plan: CEZ:AV0Z50040702
Keywords : histone deacetylase inhibitor * platinum * DNA
Subject RIV: BO - Biophysics
Impact factor: 4.570, year: 2012
Permanent Link: http://hdl.handle.net/11104/0007105 - 7.0376804 - BFÚ 2013 RIV US eng J - Journal Article
Lišková, Barbora - Zerzánková, Lenka - Nováková, Olga - Kostrhunová, Hana - Trávníček, Z. - Brabec, Viktor
Cellular response to antitumor cis-dichlorido platinum(II) complexes of CDK inhibitor bohemine and its analogues.
Chemical Research in Toxicology. Roč. 25, č. 2 (2012), s. 500-509. ISSN 0893-228X. E-ISSN 1520-5010
R&D Projects: GA ČR(CZ) GD301/09/H004; GA ČR(CZ) GAP301/10/0598
Keywords : cisplatin * DNA * bohemine
Subject RIV: BO - Biophysics
Impact factor: 3.667, year: 2012
Permanent Link: http://hdl.handle.net/11104/0209114 - 8.0373400 - BFÚ 2012 RIV US eng J - Journal Article
Kašpárková, Jana - Suchánková, T. - Halámiková, Anna - Zerzánková, Lenka - Vrána, Oldřich - Margiotta, N. - Natile, G. - Brabec, Viktor
Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring PtII chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligand.
Biochemical Pharmacology. Roč. 79, č. 4 (2010), s. 552-564. ISSN 0006-2952. E-ISSN 1873-2968
R&D Projects: GA MŠMT(CZ) LC06030; GA AV ČR(CZ) KAN200200651
Keywords : DNA * platinum * cancer
Subject RIV: BO - Biophysics
Impact factor: 4.889, year: 2010
Permanent Link: http://hdl.handle.net/11104/0206508 - 9.0373396 - BFÚ 2012 RIV US eng J - Journal Article
Zerzánková, Lenka - Suchánková, T. - Vrána, Oldřich - Farrell, N.P. - Brabec, Viktor
Conformation and recognition of DNA modified by a new antitumor dinuclear PtII complex resistant to decomposition by sulfur nucleophiles.
Biochemical Pharmacology. Roč. 79, č. 2 (2010), s. 112-121. ISSN 0006-2952. E-ISSN 1873-2968
R&D Projects: GA MŠMT(CZ) LC06030; GA AV ČR(CZ) KAN200200651
Keywords : antitumor * dinuclear platinum complex * DNA damage
Subject RIV: BO - Biophysics
Impact factor: 4.889, year: 2010
Permanent Link: http://hdl.handle.net/11104/0206505 - 10.0373395 - BFÚ 2012 RIV US eng J - Journal Article
Zerzánková, Lenka - Kostrhunová, Hana - Vojtíšková, Marie - Nováková, Olga - Suchánková, T. - Lin, M. - Guo, Z. - Kašpárková, Jana - Brabec, Viktor
Mechanistic insights into antitumor effects of new dinuclear cis PtII complexes containing aromatic linkers.
Biochemical Pharmacology. Roč. 80, č. 3 (2010), s. 344-351. ISSN 0006-2952. E-ISSN 1873-2968
R&D Projects: GA MŠMT(CZ) LC06030; GA AV ČR(CZ) KAN200200651
Keywords : DNA * platinum * cancer
Subject RIV: BO - Biophysics
Impact factor: 4.889, year: 2010
Permanent Link: http://hdl.handle.net/11104/0206504