Search results
- 1.0368775 - BFÚ 2012 RIV US eng J - Journal Article
Westendorf, A.F. - Zerzánková, Lenka - Salassa, L. - Sadler, P.J. - Brabec, Viktor - Bednarski, P.J.
Influence of pyridine versus piperidine ligands on the chemical, DNA binding and cytotoxic properties of light activated trans,trans,trans-[Pt(N3)2(OH)2(NH3)(L)].
Journal of Inorganic Biochemistry. Roč. 105, č. 5 (2011), s. 652-662. ISSN 0162-0134. E-ISSN 1873-3344
R&D Projects: GA AV ČR(CZ) IAA400040803; GA ČR(CZ) GD301/09/H004; GA ČR(CZ) GAP301/10/0598
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : platinum azides * cisplatin * photoactivation
Subject RIV: BO - Biophysics
Impact factor: 3.354, year: 2011
Permanent Link: http://hdl.handle.net/11104/0203023 - 2.0366089 - BFÚ 2012 RIV DE eng J - Journal Article
Malina, Jaroslav - Farrell, N.P. - Brabec, Viktor
DNA interstrand cross-links of an antitumor trinuclear platinum(II) complex: Thermodynamic analysis and chemical probing.
Chemistry-An Asian Journal. Roč. 6, č. 6 (2011), s. 1566-1574. ISSN 1861-4728. E-ISSN 1861-471X
R&D Projects: GA MŠMT(CZ) LC06030; GA MŠMT(CZ) ME10066; GA AV ČR(CZ) IAA400040803; GA ČR(CZ) GAP301/10/0598; GA ČR(CZ) GAP205/11/0856
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : calorimetry * DNA damage * interstrand cross-link
Subject RIV: BO - Biophysics
Impact factor: 4.500, year: 2011
Permanent Link: http://hdl.handle.net/11104/0201180 - 3.0358135 - BFÚ 2011 RIV GB eng J - Journal Article
Malina, Jaroslav - Kašpárková, J. - Farrell, N.P. - Brabec, Viktor
Walking of antitumor bifunctional trinuclear PtII complex on double-helical DNA.
Nucleic Acids Research. Roč. 39, č. 2 (2011), s. 720-728. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA MŠMT(CZ) ME08017; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) IAA400040803; GA MŠMT(CZ) ME10066
Grant - others:GA MŠk(CZ) LC06030; GA MŠk(CZ) OC09018; GA AV ČR(CZ) KAN200200651
Program: LC; KA
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : BBR3464 * DNA * cross-link
Subject RIV: BO - Biophysics
Impact factor: 8.026, year: 2011
Permanent Link: http://hdl.handle.net/11104/0196242 - 4.0353781 - BFÚ 2011 RIV US eng J - Journal Article
Kostrhunová, Hana - Vrána, Oldřich - Suchánková, T. - Gibson, D. - Kašpárková, Jana - Brabec, Viktor
Different features of the DNA binding mode of antitumor cis-amminedichlorido(cyclohexylamine)platinum(II) (JM118) and cisplatin in vitro.
Chemical Research in Toxicology. Roč. 23, č. 11 (2010), s. 1833-1842. ISSN 0893-228X. E-ISSN 1520-5010
R&D Projects: GA MŠMT(CZ) ME08017; GA MŠMT(CZ) ME10066; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) IAA400040803; GA ČR(CZ) GAP301/10/0598
Grant - others:GA MŠk(CZ) LC06030; GA MŠk(CZ) OC09018; GA AV ČR(CZ) KAN200200651
Program: LC; KA
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : JM118 * DNA bending * DNA-protein cross-linking
Subject RIV: BO - Biophysics
Impact factor: 4.148, year: 2010
Permanent Link: http://hdl.handle.net/11104/0192929 - 5.0353777 - BFÚ 2011 RIV US eng J - Journal Article
Kostrhunová, Hana - Kašpárková, Jana - Gibson, D. - Brabec, Viktor
Studies on cellular accumulation of satraplatin and its major metabolite JM118 and their interactions with glutathione.
Molecular Pharmaceutics. Roč. 7, č. 6 (2010), s. 2093-2102. ISSN 1543-8384. E-ISSN 1543-8392
R&D Projects: GA MŠMT(CZ) ME08017; GA MŠMT(CZ) ME10066; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) IAA400040803; GA ČR(CZ) GAP301/10/0598
Grant - others:GA MŠk(CZ) LC06030; GA AV ČR(CZ) KAN200200651
Program: LC; KA
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : JM118 * cellular accumulation * glutathione
Subject RIV: BO - Biophysics
Impact factor: 5.400, year: 2010
Permanent Link: http://hdl.handle.net/11104/0006241 - 6.0347441 - BFÚ 2011 RIV US eng J - Journal Article
Zerzánková, Lenka - Kostrhunová, Hana - Vojtíšková, Marie - Nováková, Olga - Suchánková, T. - Lin, M. - Guo, Z. - Kašpárková, Jana - Brabec, Viktor
Mechanistic insights into antitumor effects of new dinuclear cis PtII complexes containing aromatic linkers.
Biochemical Pharmacology. Roč. 80, č. 3 (2010), s. 344-351. ISSN 0006-2952. E-ISSN 1873-2968
R&D Projects: GA MŠMT(CZ) LC06030; GA MŠMT(CZ) ME08017; GA MŠMT(CZ) ME10066; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) IAA400040803; GA ČR(CZ) GD301/09/H004; GA ČR(CZ) GAP301/10/0598
Grant - others:GA MŠk(CZ) OC09018; GA AV ČR(CZ) KAN200200651
Program: KA
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : DNA * platinum * cancer
Subject RIV: BO - Biophysics
Impact factor: 4.889, year: 2010
Permanent Link: http://hdl.handle.net/11104/0188216 - 7.0347184 - BFÚ 2011 RIV US eng J - Journal Article
Kašpárková, Jana - Suchánková, T. - Halámiková, Anna - Zerzánková, Lenka - Vrána, Oldřich - Margiotta, N. - Natile, G. - Brabec, Viktor
Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring PtII chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligand.
Biochemical Pharmacology. Roč. 79, č. 4 (2010), s. 552-564. ISSN 0006-2952. E-ISSN 1873-2968
R&D Projects: GA MŠMT(CZ) LC06030; GA MŠMT(CZ) ME08017; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) 1QS500040581; GA AV ČR(CZ) KAN200200651; GA AV ČR(CZ) IAA400040803; GA AV ČR(CZ) GD301/09/H004
Grant - others:GA MŠk(CZ) OC09018
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : DNA * platinum * cancer
Subject RIV: BO - Biophysics
Impact factor: 4.889, year: 2010
Permanent Link: http://hdl.handle.net/11104/0188017 - 8.0347183 - BFÚ 2011 RIV US eng J - Journal Article
Biton, A. - Ezra, A. - Kašpárková, Jana - Brabec, Viktor - Yavin, E.
DNA photocleavage by DNA and DNA-LNA amino acid-dye conjugates.
Bioconjugate Chemistry. Roč. 21, č. 4 (2010), s. 616-621. ISSN 1043-1802. E-ISSN 1520-4812
R&D Projects: GA AV ČR(CZ) IAA400040803
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : DNA * photocleavage * triplex forming oligonucleotides
Subject RIV: BO - Biophysics
Impact factor: 5.002, year: 2010
Permanent Link: http://hdl.handle.net/11104/0188016 - 9.0347181 - BFÚ 2011 RIV US eng J - Journal Article
Alkhader, S. - Ezra, A. - Kašpárková, Jana - Brabec, Viktor - Yavin, E.
A metal-free DNA nuclease based on a cyclic peptide scaffold.
Bioconjugate Chemistry. Roč. 21, č. 8 (2010), s. 1425-1431. ISSN 1043-1802. E-ISSN 1520-4812
R&D Projects: GA AV ČR(CZ) IAA400040803; GA MŠMT(CZ) LC06030; GA MŠMT(CZ) ME08017; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) KAN200200651
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : DNA * cleavage * chemical nuclease
Subject RIV: BO - Biophysics
Impact factor: 5.002, year: 2010
Permanent Link: http://hdl.handle.net/11104/0188014 - 10.0332052 - BFÚ 2010 RIV GB eng J - Journal Article
Malina, Jaroslav - Vrána, Oldřich - Brabec, Viktor
Mechanistic studies of the modulation of cleavage activity of topoisomerase I by DNA adducts of mono- and bi-functional Pt-II complexes.
[Mechanistická studie modulace štěpící aktivity topoisomerázy I vlivem mono- a bifunkčních aduktů platnatých komplexů na DNA.]
Nucleic Acids Research. Roč. 37, č. 16 (2009), s. 5432-5442. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA MŠMT(CZ) LC06030; GA MŠMT(CZ) ME08017; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) 1QS500040581; GA AV ČR(CZ) KAN200200651; GA AV ČR(CZ) IAA400040803
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : cisplatin * camptothecin * topoisomerase I
Subject RIV: BO - Biophysics
Impact factor: 7.479, year: 2009
Permanent Link: http://hdl.handle.net/11104/0177406