Search results

  1. 1.
    0368775 - BFÚ 2012 RIV US eng J - Journal Article
    Westendorf, A.F. - Zerzánková, Lenka - Salassa, L. - Sadler, P.J. - Brabec, Viktor - Bednarski, P.J.
    Influence of pyridine versus piperidine ligands on the chemical, DNA binding and cytotoxic properties of light activated trans,trans,trans-[Pt(N3)2(OH)2(NH3)(L)].
    Journal of Inorganic Biochemistry. Roč. 105, č. 5 (2011), s. 652-662. ISSN 0162-0134. E-ISSN 1873-3344
    R&D Projects: GA AV ČR(CZ) IAA400040803; GA ČR(CZ) GD301/09/H004; GA ČR(CZ) GAP301/10/0598
    Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Keywords : platinum azides * cisplatin * photoactivation
    Subject RIV: BO - Biophysics
    Impact factor: 3.354, year: 2011
    Permanent Link: http://hdl.handle.net/11104/0203023
     
     
  2. 2.
    0366089 - BFÚ 2012 RIV DE eng J - Journal Article
    Malina, Jaroslav - Farrell, N.P. - Brabec, Viktor
    DNA interstrand cross-links of an antitumor trinuclear platinum(II) complex: Thermodynamic analysis and chemical probing.
    Chemistry-An Asian Journal. Roč. 6, č. 6 (2011), s. 1566-1574. ISSN 1861-4728. E-ISSN 1861-471X
    R&D Projects: GA MŠMT(CZ) LC06030; GA MŠMT(CZ) ME10066; GA AV ČR(CZ) IAA400040803; GA ČR(CZ) GAP301/10/0598; GA ČR(CZ) GAP205/11/0856
    Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Keywords : calorimetry * DNA damage * interstrand cross-link
    Subject RIV: BO - Biophysics
    Impact factor: 4.500, year: 2011
    Permanent Link: http://hdl.handle.net/11104/0201180
     
     
  3. 3.
    0358135 - BFÚ 2011 RIV GB eng J - Journal Article
    Malina, Jaroslav - Kašpárková, J. - Farrell, N.P. - Brabec, Viktor
    Walking of antitumor bifunctional trinuclear PtII complex on double-helical DNA.
    Nucleic Acids Research. Roč. 39, č. 2 (2011), s. 720-728. ISSN 0305-1048. E-ISSN 1362-4962
    R&D Projects: GA MŠMT(CZ) ME08017; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) IAA400040803; GA MŠMT(CZ) ME10066
    Grant - others:GA MŠk(CZ) LC06030; GA MŠk(CZ) OC09018; GA AV ČR(CZ) KAN200200651
    Program: LC; KA
    Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Keywords : BBR3464 * DNA * cross-link
    Subject RIV: BO - Biophysics
    Impact factor: 8.026, year: 2011
    Permanent Link: http://hdl.handle.net/11104/0196242
     
     
  4. 4.
    0353781 - BFÚ 2011 RIV US eng J - Journal Article
    Kostrhunová, Hana - Vrána, Oldřich - Suchánková, T. - Gibson, D. - Kašpárková, Jana - Brabec, Viktor
    Different features of the DNA binding mode of antitumor cis-amminedichlorido(cyclohexylamine)platinum(II) (JM118) and cisplatin in vitro.
    Chemical Research in Toxicology. Roč. 23, č. 11 (2010), s. 1833-1842. ISSN 0893-228X. E-ISSN 1520-5010
    R&D Projects: GA MŠMT(CZ) ME08017; GA MŠMT(CZ) ME10066; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) IAA400040803; GA ČR(CZ) GAP301/10/0598
    Grant - others:GA MŠk(CZ) LC06030; GA MŠk(CZ) OC09018; GA AV ČR(CZ) KAN200200651
    Program: LC; KA
    Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Keywords : JM118 * DNA bending * DNA-protein cross-linking
    Subject RIV: BO - Biophysics
    Impact factor: 4.148, year: 2010
    Permanent Link: http://hdl.handle.net/11104/0192929
     
     
  5. 5.
    0353777 - BFÚ 2011 RIV US eng J - Journal Article
    Kostrhunová, Hana - Kašpárková, Jana - Gibson, D. - Brabec, Viktor
    Studies on cellular accumulation of satraplatin and its major metabolite JM118 and their interactions with glutathione.
    Molecular Pharmaceutics. Roč. 7, č. 6 (2010), s. 2093-2102. ISSN 1543-8384. E-ISSN 1543-8392
    R&D Projects: GA MŠMT(CZ) ME08017; GA MŠMT(CZ) ME10066; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) IAA400040803; GA ČR(CZ) GAP301/10/0598
    Grant - others:GA MŠk(CZ) LC06030; GA AV ČR(CZ) KAN200200651
    Program: LC; KA
    Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Keywords : JM118 * cellular accumulation * glutathione
    Subject RIV: BO - Biophysics
    Impact factor: 5.400, year: 2010
    Permanent Link: http://hdl.handle.net/11104/0006241
     
     
  6. 6.
    0347441 - BFÚ 2011 RIV US eng J - Journal Article
    Zerzánková, Lenka - Kostrhunová, Hana - Vojtíšková, Marie - Nováková, Olga - Suchánková, T. - Lin, M. - Guo, Z. - Kašpárková, Jana - Brabec, Viktor
    Mechanistic insights into antitumor effects of new dinuclear cis PtII complexes containing aromatic linkers.
    Biochemical Pharmacology. Roč. 80, č. 3 (2010), s. 344-351. ISSN 0006-2952. E-ISSN 1873-2968
    R&D Projects: GA MŠMT(CZ) LC06030; GA MŠMT(CZ) ME08017; GA MŠMT(CZ) ME10066; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) IAA400040803; GA ČR(CZ) GD301/09/H004; GA ČR(CZ) GAP301/10/0598
    Grant - others:GA MŠk(CZ) OC09018; GA AV ČR(CZ) KAN200200651
    Program: KA
    Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Keywords : DNA * platinum * cancer
    Subject RIV: BO - Biophysics
    Impact factor: 4.889, year: 2010
    Permanent Link: http://hdl.handle.net/11104/0188216
     
     
  7. 7.
    0347184 - BFÚ 2011 RIV US eng J - Journal Article
    Kašpárková, Jana - Suchánková, T. - Halámiková, Anna - Zerzánková, Lenka - Vrána, Oldřich - Margiotta, N. - Natile, G. - Brabec, Viktor
    Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring PtII chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligand.
    Biochemical Pharmacology. Roč. 79, č. 4 (2010), s. 552-564. ISSN 0006-2952. E-ISSN 1873-2968
    R&D Projects: GA MŠMT(CZ) LC06030; GA MŠMT(CZ) ME08017; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) 1QS500040581; GA AV ČR(CZ) KAN200200651; GA AV ČR(CZ) IAA400040803; GA AV ČR(CZ) GD301/09/H004
    Grant - others:GA MŠk(CZ) OC09018
    Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Keywords : DNA * platinum * cancer
    Subject RIV: BO - Biophysics
    Impact factor: 4.889, year: 2010
    Permanent Link: http://hdl.handle.net/11104/0188017
     
     
  8. 8.
    0347183 - BFÚ 2011 RIV US eng J - Journal Article
    Biton, A. - Ezra, A. - Kašpárková, Jana - Brabec, Viktor - Yavin, E.
    DNA photocleavage by DNA and DNA-LNA amino acid-dye conjugates.
    Bioconjugate Chemistry. Roč. 21, č. 4 (2010), s. 616-621. ISSN 1043-1802. E-ISSN 1520-4812
    R&D Projects: GA AV ČR(CZ) IAA400040803
    Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Keywords : DNA * photocleavage * triplex forming oligonucleotides
    Subject RIV: BO - Biophysics
    Impact factor: 5.002, year: 2010
    Permanent Link: http://hdl.handle.net/11104/0188016
     
     
  9. 9.
    0347181 - BFÚ 2011 RIV US eng J - Journal Article
    Alkhader, S. - Ezra, A. - Kašpárková, Jana - Brabec, Viktor - Yavin, E.
    A metal-free DNA nuclease based on a cyclic peptide scaffold.
    Bioconjugate Chemistry. Roč. 21, č. 8 (2010), s. 1425-1431. ISSN 1043-1802. E-ISSN 1520-4812
    R&D Projects: GA AV ČR(CZ) IAA400040803; GA MŠMT(CZ) LC06030; GA MŠMT(CZ) ME08017; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) KAN200200651
    Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Keywords : DNA * cleavage * chemical nuclease
    Subject RIV: BO - Biophysics
    Impact factor: 5.002, year: 2010
    Permanent Link: http://hdl.handle.net/11104/0188014
     
     
  10. 10.
    0332052 - BFÚ 2010 RIV GB eng J - Journal Article
    Malina, Jaroslav - Vrána, Oldřich - Brabec, Viktor
    Mechanistic studies of the modulation of cleavage activity of topoisomerase I by DNA adducts of mono- and bi-functional Pt-II complexes.
    [Mechanistická studie modulace štěpící aktivity topoisomerázy I vlivem mono- a bifunkčních aduktů platnatých komplexů na DNA.]
    Nucleic Acids Research. Roč. 37, č. 16 (2009), s. 5432-5442. ISSN 0305-1048. E-ISSN 1362-4962
    R&D Projects: GA MŠMT(CZ) LC06030; GA MŠMT(CZ) ME08017; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) 1QS500040581; GA AV ČR(CZ) KAN200200651; GA AV ČR(CZ) IAA400040803
    Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Keywords : cisplatin * camptothecin * topoisomerase I
    Subject RIV: BO - Biophysics
    Impact factor: 7.479, year: 2009
    Permanent Link: http://hdl.handle.net/11104/0177406
     
     

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