Search results
- 1.0574493 - BC 2024 RIV NL eng J - Journal Article
Straková, Petra - Bednář, Petr - Kotouček, J. - Holoubek, Jiří - Fořtová, A. - Svoboda, Pavel - Štefánik, M. - Huvarová, I. - Šimečková, P. - Mašek, J. - Gvozdev, D.A. - Mikhnovets, I.E. - Chistov, A.A. - Nikitin, T.D. - Krasilnikov, M.S. - Ustinov, A. - Alferova, V.A. - Korshun, V.A. - Růžek, Daniel - Eyer, Luděk
Antiviral activity of singlet oxygen-photogenerating perylene compounds against SARS-CoV-2: Interaction with the viral envelope and photodynamic virion inactivation.
Virus Research. Roč. 334, SEPT (2023), č. článku 199158. ISSN 0168-1702. E-ISSN 1872-7492
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:60077344
Keywords : SARS-CoV-2 * Perylene-related compound * Antiviral activity * Membrane * Liposome * Photodynamic inactivation
OECD category: Virology
Impact factor: 5, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S016817022300120X?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0345239File Download Size Commentary Version Access Strakova_2023_VirRes.pdf 1 11.7 MB Publisher’s postprint open-access - 2.0556112 - BFÚ 2023 RIV NL eng J - Journal Article
Šimečková, P. - Pěnčíková, K. - Kováč, O. - Slavík, J. - Parenicova, M. - Vondráček, Jan - Machala, M.
In vitro profiling of toxic effects of environmental polycyclic aromatic hydrocarbons on nuclear receptor signaling, disruption of endogenous metabolism and induction of cellular stress.
Science of the Total Environment. Roč. 815, APR 1 2022 (2022), č. článku 151967. ISSN 0048-9697. E-ISSN 1879-1026
R&D Projects: GA ČR(CZ) GA21-00533S
Institutional support: RVO:68081707
Keywords : pregnane-x-receptor * primary human hepatocytes * aryl-hydrocarbon * estrogen-receptor * mediated activity * hepg2 cells * cross-talk * activation
OECD category: Ecology
Impact factor: 9.8, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0048969721070431?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0339759 - 3.0524868 - ÚFCH JH 2021 RIV CH eng J - Journal Article
Švadláková, T. - Hubatka, F. - Knötigová, P.T. - Kulich, P. - Mašek, J. - Kotouček, J. - Macák, J. - Motola, M. - Kalbáč, Martin - Koláčková, M. - Vaňková, R. - Vicherková, P. - Málková, A. - Šimečková, P. - Volkov, Y. - Prina-Mello, A. - Kratochvílová, Irena - Fiala, Z. - Raška, M. - Krejsek, J. - Turánek, J.
Proinflammatory Effect of Carbon-Based Nanomaterials: In Vitro Study on Stimulation of Inflammasome NLRP3 via Destabilisation of Lysosomes.
Nanomaterials. Roč. 10, č. 3 (2020), č. článku 418. E-ISSN 2079-4991
R&D Projects: GA MŠMT(CZ) EF16_019/0000760; GA MŠMT(CZ) LM2015088; GA MŠMT(CZ) EF16_013/0001821
Grant - others:OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760
Institutional support: RVO:61388955 ; RVO:68378271
Keywords : functionalized graphene oxide * pristine graphene * oxidative stress * nanoplatelets * nanotubes * toxicity * release * single * system * inflammogenicity * graphene platelets * carbon nanotubes * inflammasome NLRP3 * cathepsin B * macrophages * thp-1
OECD category: Physical chemistry; Biophysics (FZU-D)
Impact factor: 5.076, year: 2020
Method of publishing: Open access
Permanent Link: http://hdl.handle.net/11104/0309112File Download Size Commentary Version Access 0524868.pdf 1 2 MB open access Publisher’s postprint open-access - 4.0509040 - ÚPT 2020 RIV US eng J - Journal Article
Knötigová, P.T. - Mašek, J. - Hubatka, F. - Kotouček, J. - Kulich, P. - Šimečková, P. - Bartheldyová, E. - Machala, M. - Švadláková, T. - Krejsek, J. - Vaškovicová, Naděžda - Skoupý, Radim - Krzyžánek, Vladislav - Macaulay, V. - Katzuba, M. - Fekete, Ladislav - Ashcheulov, Petr - Raška, M. - Kratochvílová, Irena - Turánek, J.
Application of Advanced Microscopic Methods to Study the Interaction of Carboxylated Fluorescent Nanodiamonds with Membrane Structures in THP-1 Cells: Activation of Inflammasome NLRP3 as the Result of Lysosome Destabilization.
Molecular Pharmaceutics. Roč. 16, č. 8 (2019), s. 3441-3451. ISSN 1543-8384. E-ISSN 1543-8392
R&D Projects: GA MŠMT(CZ) EF16_019/0000760; GA ČR GA17-15451S; GA MŠMT(CZ) LO1212; GA MŠMT ED0017/01/01
Grant - others:OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760
Institutional support: RVO:68081731 ; RVO:68378271
Keywords : fluorescent nanodiamonds * cell immunopathology * nanodiamond intercellular distribution * inflammation * inflammasome NLRP3 * AFM * TEM * cathodoluminescence
OECD category: Nano-processes (applications on nano-scale); Biophysics (FZU-D)
Impact factor: 4.321, year: 2019
Method of publishing: Limited access
https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.9b00225
Permanent Link: http://hdl.handle.net/11104/0299848 - 5.0394860 - BFÚ 2014 RIV US eng J - Journal Article
Procházková, Jiřina - Kabátková, Markéta - Šmerdová, Lenka - Pachernik, J. - Sýkorová, D. - Kohoutek, J. - Šimečková, P. - Hrubá, E. - Kozubík, Alois - Machala, M. - Vondráček, Jan
Aryl Hydrocarbon Receptor Negatively Regulates Expression of the Plakoglobin Gene (Jup).
Toxicological Sciences. Roč. 134, č. 2 (2013), s. 258-270. ISSN 1096-6080. E-ISSN 1096-0929
R&D Projects: GA ČR(CZ) GA524/09/1337; GA ČR(CZ) GD204/09/H058; GA MŠMT(CZ) EE2.3.30.0030
Grant - others:GA ČR(CZ) GA301/09/1832
Institutional research plan: CEZ:AV0Z50040702
Institutional support: RVO:68081707
Keywords : EMBRYONIC STEM-CELLS * LIVER EPITHELIAL-CELLS * AH RECEPTOR
Subject RIV: BO - Biophysics
Impact factor: 4.478, year: 2013
Permanent Link: http://hdl.handle.net/11104/0223042 - 6.0392604 - BFÚ 2014 RIV DE eng J - Journal Article
Andrysík, Zdeněk (ed.) - Procházková, Jiřina - Kabátková, Markéta - Umannová, Lenka - Šimečková, P. - Kohoutek, J. - Machala, M. - Vondráček, Jan … Total 9 authors
Aryl hydrocarbon receptor-mediated disruption of contact inhibition is associated with connexin43 downregulation and inhibition of gap junctional intercellular communication.
Archives of Toxicology. Roč. 87, č. 3 (2013), s. 491-503. ISSN 0340-5761. E-ISSN 1432-0738
R&D Projects: GA ČR(CZ) GA524/09/1337
Institutional research plan: CEZ:AV0Z50040702
Institutional support: RVO:68081707
Keywords : POLYCYCLIC AROMATIC-HYDROCARBONS * LIVER EPITHELIAL-CELLS * RAT-LIVER * GENE-EXPRESSION
Subject RIV: BO - Biophysics
Impact factor: 5.078, year: 2013
Permanent Link: http://hdl.handle.net/11104/0221434 - 7.0360304 - BFÚ 2012 RIV US eng J - Journal Article
Hamers, T. - Kamstra, J.H. - Cenijn, P.H. - Pěnčíková, K. - Palková, L. - Šimečková, P. - Vondráček, Jan - Andersson, P.L. - Stenberg, M. - Machala, M.
In vitro toxicity profiling of ultrapure non-dioxin-like polychlorinated biphenyl congeners and their relative toxic contribution to PCB mixtures in humans.
Toxicological Sciences. Roč. 121, č. 1 (2011), s. 88-100. ISSN 1096-6080. E-ISSN 1096-0929
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : NDL-PCBs * endocrine disruption * relative toxic potencies
Subject RIV: BO - Biophysics
Impact factor: 4.652, year: 2011
Permanent Link: http://hdl.handle.net/11104/0197885 - 8.0327032 - BFÚ 2010 RIV NL eng J - Journal Article
Šimečková, P. - Vondráček, J. - Procházková, J. - Kozubík, Alois - Krčmář, P. - Machala, M.
2,2', 4,4',5,5'-Hexachlorobiphenyl (PCB 153) induces degradation of adherens junction proteins and inhibits beta-catenin-dependent transcription in liver epithelial cells.
[2,2', 4,4',5,5'-Hexachlorobiphenyl (PCB 153) způsobuje degradaci proteinů tvořících adherentní spoje a inhibuje v jaterních epiteliálních buňkách transkripci kontrolovanou beta-kateninem.]
Toxicology. Roč. 260, 1-3 (2009), s. 104-111. ISSN 0300-483X
R&D Projects: GA ČR(CZ) GA524/06/0517
Grant - others:GA ČR(CZ) GA524/09/1337
Program: GA
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : polychlorinated biphenyls * E-cadherin * beta-catenin
Subject RIV: BO - Biophysics
Impact factor: 3.241, year: 2009
Permanent Link: http://hdl.handle.net/11104/0173940 - 9.0318647 - BFÚ 2009 RIV US eng J - Journal Article
Šimečková, P. - Vondráček, Jan - Andrysík, Zdeněk - Zatloukalová, Jiřina - Krčmář, P. - Kozubík, Alois - Machala, M.
The 2,2',4,4',5,5'-hexachlorobiphenyl-enhanced degradation of connexin 43 involves both proteasomal and lysosomal activities.
[2,2',4,4',5,5'-hexachlorobifenyl (PCB 153) posiluje degradaci konexinu43 prostřednictvím proteazomálních a lysozomálních aktivit.]
Toxicological Sciences. Roč. 107, č. 1 (2009), s. 9-18. ISSN 1096-6080. E-ISSN 1096-0929
R&D Projects: GA ČR(CZ) GA524/06/0517
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : PCBs * connexin * gap junctions
Subject RIV: BO - Biophysics
Impact factor: 4.814, year: 2009
Permanent Link: http://hdl.handle.net/11104/0168005 - 10.0311096 - BFÚ 2009 RIV NL eng J - Journal Article
Kummer, V. - Mašková, J. - Zralý, Z. - Neča, J. - Šimečková, P. - Vondráček, Jan - Machala, M.
Estrogenic activity of environmental polycyclic aromatic hydrocarbons in uterus of immature Wistar rats.
[Estrogenní aktivita environmentálních polycyklických aromatických uhlovodíků v dělohách prepubertálních potkanů kmene Wistar.]
Toxicology Letters. Roč. 180, č. 3 (2008), s. 212-221. ISSN 0378-4274. E-ISSN 1879-3169
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : polycyclic aromatic hydrocarbons * rat immature uterothrophic assay * estrogen receptor
Subject RIV: BO - Biophysics
Impact factor: 3.249, year: 2008
Permanent Link: http://hdl.handle.net/11104/0162800