Search results
- 1.0544612 - BFÚ 2022 RIV DE eng J - Journal Article
de Paiva, R. E. F. - Peterson, E. J. - Malina, Jaroslav - Zoepfl, M. - Hampton, J. D. - Johnson, W. E. - Graminha, A. - Ourahmane, A. - McVoy, M. A. - Brabec, Viktor - Berners-Price, S.J. - Farrell, N.P.
On the Biology of Werner's Complex.
Angewandte Chemie - International Edition. Roč. 60, č. 31 (2021), s. 17123-17130. ISSN 1433-7851. E-ISSN 1521-3773
R&D Projects: GA ČR(CZ) GC20-14082J
Institutional support: RVO:68081707
Keywords : heparan-sulfate proteoglycan * platinum complexes * cell-surface * dna-binding * entry * recognition
OECD category: Physical chemistry
Impact factor: 16.823, year: 2021
Method of publishing: Open access
https://onlinelibrary.wiley.com/doi/10.1002/anie.202105019
Permanent Link: http://hdl.handle.net/11104/0321449 - 2.0536128 - BFÚ 2021 RIV US eng J - Journal Article
Malina, Jaroslav - Farrell, N.P. - Brabec, Viktor
Substitution-Inert Polynuclear Platinum Complexes Inhibit Reverse Transcription Preferentially in RNA Triplex-Forming Templates.
Inorganic Chemistry. Roč. 59, č. 20 (2020), s. 15135-15143. ISSN 0020-1669. E-ISSN 1520-510X
R&D Projects: GA ČR(CZ) GC20-14082J
Institutional support: RVO:68081707
Keywords : RNA * Triplex-Forming * Substitution-Inert Polynuclear Platinum Complexes
OECD category: Inorganic and nuclear chemistry
Impact factor: 5.165, year: 2020
Method of publishing: Limited access
https://pubs.acs.org/doi/10.1021/acs.inorgchem.0c02070
Permanent Link: http://hdl.handle.net/11104/0313952 - 3.0535937 - BFÚ 2021 RIV DE eng J - Journal Article
Brabec, Viktor - Kašpárková, Jana - Menon, V. - Farrell, N.P.
Polynuclear Platinum Complexes. Structural Diversity and DNA Binding.
Metal Ions in Life Sciences. Metallo-Drugs: Development and Action of Anticancer Agents. - (Sigel, A.; Sigel, H.; Freisinger, E.; Sigel, R.). Roč. 18, č. 2018 (2018), s. 43-68. ISBN 978-3-11-047073-4. ISSN 1559-0836
Institutional support: RVO:68081707
Keywords : interstrand cross-links * pt-ii complex * nf-kappa-b * cell-cycle progression * group domain proteins * dinuclear-platinum * geometric isomerism
OECD category: Pharmacology and pharmacy
Method of publishing: Limited access
https://www.degruyter.com/view/title/518384
Permanent Link: http://hdl.handle.net/11104/0313805 - 4.0510161 - BFÚ 2020 US eng J - Journal Article
Malina, Jaroslav - Čechová, Klára - Farrell, N.P. - Brabec, Viktor
Substitution-Inert Polynuclear Platinum Complexes with Dangling Amines: Condensation/Aggregation of Nucleic Acids and Inhibition of DNA-Related Enzymatic Activities.
Inorganic Chemistry. Roč. 58, č. 10 (2019), s. 6804-6810. ISSN 0020-1669. E-ISSN 1520-510X
Keywords : transcriptional activity * topoisomerase-i * phosphate clamp * molecules * enhancement
Impact factor: 4.825, year: 2019
Method of publishing: Limited access
https://pubs.acs.org/doi/10.1021/acs.inorgchem.9b00254
Permanent Link: http://hdl.handle.net/11104/0300706 - 5.0504519 - BFÚ 2020 RIV DE eng J - Journal Article
Malina, Jaroslav - Farrell, N.P. - Brabec, Viktor
Substitution-Inert Polynuclear Platinum Complexes Act as Potent Inducers of Condensation/Aggregation of Short Single- and Double-Stranded DNA and RNA Oligonucleotides.
Chemistry - A European Journal. Roč. 25, č. 12 (2019), s. 2995-2999. ISSN 0947-6539. E-ISSN 1521-3765
R&D Projects: GA ČR GA16-03517S
Institutional support: RVO:68081707
Keywords : phosphate clamp * recognition * selectivity * length
OECD category: Physical chemistry
Impact factor: 4.857, year: 2019
Method of publishing: Limited access
https://onlinelibrary.wiley.com/doi/abs/10.1002/chem.201806276
Permanent Link: http://hdl.handle.net/11104/0296135 - 6.0502569 - BFÚ 2019 RIV GB eng J - Journal Article
Nováková, Olga - Farrell, N.P. - Brabec, Viktor
Translesion DNA synthesis across double-base lesions derived from cross-links of an antitumor trinuclear platinum compound: primer extension, conformational and thermodynamic studies.
Metallomics. Roč. 10, č. 1 (2018), s. 132-144. ISSN 1756-5901. E-ISSN 1756-591X
R&D Projects: GA ČR GA17-09436S
Institutional support: RVO:68081707
Keywords : group domain proteins * i klenow fragment * polymerase-i * duplex dna
OECD category: Biochemistry and molecular biology
Impact factor: 3.571, year: 2018
Permanent Link: http://hdl.handle.net/11104/0294472 - 7.0502432 - BFÚ 2019 RIV DE eng J - Journal Article
Malina, Jaroslav - Farrell, N.P. - Brabec, Viktor
Substitution-Inert Polynuclear Platinum Complexes That Inhibit the Activity of DNA Polymerase in Triplex-Forming Templates.
Angewandte Chemie - International Edition. Roč. 57, č. 28 (2018), s. 8535-8539. ISSN 1433-7851. E-ISSN 1521-3773
R&D Projects: GA ČR GA16-03517S
Institutional support: RVO:68081707
Keywords : phosphate clamp * selectivity * binding * stabilization
OECD category: Organic chemistry
Impact factor: 12.257, year: 2018
Permanent Link: http://hdl.handle.net/11104/0294372 - 8.0470811 - BFÚ 2017 RIV GB eng J - Journal Article
Brabec, Viktor - Kašpárková, Jana - Kostrhunová, Hana - Farrell, N.P.
Inhibition of nuclear factor kappaB proteins-platinated DNA interactions correlates with cytotoxic effectiveness of the platinum complexes.
Scientific Reports. Roč. 6, AUG2016 (2016), č. článku 28474. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MŠMT(CZ) LH13096
Institutional support: RVO:68081707
Keywords : interstrand cross-links * group domain proteins
Subject RIV: BO - Biophysics
Impact factor: 4.259, year: 2016
Permanent Link: http://hdl.handle.net/11104/0268362 - 9.0386048 - BFÚ 2013 RIV DE eng J - Journal Article
Muchová, T. - Quintal, S.M. - Farrell, N.P. - Brabec, Viktor - Kašpárková, J.
Antitumor bifunctional dinuclear PtII complex BBR3535 forms interduplex DNA cross-links under molecular crowding conditions.
Journal of Biological Inorganic Chemistry. Roč. 17, č. 2 (2012), s. 239-245. ISSN 0949-8257. E-ISSN 1432-1327
R&D Projects: GA MŠMT(CZ) ME10066
Institutional research plan: CEZ:AV0Z50040702
Keywords : antitumor platinum * DNA * calorimetry
Subject RIV: BO - Biophysics
Impact factor: 3.353, year: 2012
Permanent Link: http://hdl.handle.net/11104/0220148 - 10.0373396 - BFÚ 2012 RIV US eng J - Journal Article
Zerzánková, Lenka - Suchánková, T. - Vrána, Oldřich - Farrell, N.P. - Brabec, Viktor
Conformation and recognition of DNA modified by a new antitumor dinuclear PtII complex resistant to decomposition by sulfur nucleophiles.
Biochemical Pharmacology. Roč. 79, č. 2 (2010), s. 112-121. ISSN 0006-2952. E-ISSN 1873-2968
R&D Projects: GA MŠMT(CZ) LC06030; GA AV ČR(CZ) KAN200200651
Keywords : antitumor * dinuclear platinum complex * DNA damage
Subject RIV: BO - Biophysics
Impact factor: 4.889, year: 2010
Permanent Link: http://hdl.handle.net/11104/0206505