Search results
- 1.0585603 - ÚOCHB 2025 RIV US eng J - Journal Article
Aubel, M. - Buchel, F. - Heames, B. - Jones, A. - Honc, O. - Bornberg-Bauer, E. - Hlouchová, Klára
High-throughput Selection of Human de novo-emerged sORFs with High Folding Potential.
Genome Biology and Evolution. Roč. 16, č. 4 (2024), č. článku evae069. ISSN 1759-6653. E-ISSN 1759-6653
Research Infrastructure: e-INFRA CZ II - 90254
Institutional support: RVO:61388963
Keywords : evolution * origin * genes
Impact factor: 3.3, year: 2022
Method of publishing: Open access
https://doi.org/10.1093/gbe/evae069
Permanent Link: https://hdl.handle.net/11104/0353293 - 2.0579061 - ÚOCHB 2024 RIV GB eng J - Journal Article
Hlouchová, Klára
Toxin rescue by a random sequence.
Nature Ecology & Evolution. Roč. 7, č. 12 (2023), s. 1963-1964. ISSN 2397-334X. E-ISSN 2397-334X
Institutional support: RVO:61388963
Keywords : random sequences * protein evolution * de novo proteins
OECD category: Biochemistry and molecular biology
Impact factor: 16.8, year: 2022
Method of publishing: Limited access
https://doi.org/10.1038/s41559-023-02252-0
Permanent Link: https://hdl.handle.net/11104/0347937 - 3.0571666 - MBÚ 2024 RIV GB eng J - Journal Article
Heames, B. - Buchel, F. - Aubel, M. - Tretyachenko, V. - Loginov, Dmitry Sergej - Novák, Petr - Lange, A. - Bornberg-Bauer, E. - Hlouchová, Klára
Experimental characterization of de novo proteins and their unevolved random-sequence counterparts.
Nature Ecology & Evolution. Roč. 7, č. 4 (2023), s. 570-580. ISSN 2397-334X. E-ISSN 2397-334X
R&D Projects: GA MŠMT(CZ) ED1.1.00/02.0109
EU Projects: European Commission(XE) 823839 - EPIC-XS
Research Infrastructure: CIISB II - 90127
Institutional support: RVO:61388971 ; RVO:61388963
Keywords : genetic selection * aggregation * prediction * evolution * signal
OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (UOCHB-X)
Impact factor: 16.8, year: 2022
Method of publishing: Open access
https://www.nature.com/articles/s41559-023-02010-2
Permanent Link: https://hdl.handle.net/11104/0343064 - 4.0569403 - ÚOCHB 2024 RIV US eng J - Journal Article
Makarov, M. - Sanchez Rocha, A. C. - Kryštůfek, Robin - Cherepashuk, I. - Dzmitruk, Volha - Charnavets, Tatsiana - Faustino, A. M. - Lebl, Michal - Fujishima, K. - Fried, S. D. - Hlouchová, Klára
Early Selection of the Amino Acid Alphabet Was Adaptively Shaped by Biophysical Constraints of Foldability.
Journal of the American Chemical Society. Roč. 145, č. 9 (2023), s. 5320-5329. ISSN 0002-7863. E-ISSN 1520-5126
R&D Projects: GA MŠMT(CZ) LM2018127; GA MŠMT(CZ) EF18_046/0015974
Institutional support: RVO:61388963 ; RVO:86652036
Keywords : intramolecular aminolysis * peptides * protein
OECD category: Biochemistry and molecular biology
Impact factor: 15, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/jacs.2c12987
Permanent Link: https://hdl.handle.net/11104/0340722 - 5.0559020 - ÚOCHB 2023 RIV GB eng J - Journal Article
Tretyachenko, V. - Vymětal, Jiří - Neuwirthova, T. - Vondrášek, Jiří - Fujishima, K. - Hlouchová, Klára
Modern and prebiotic amino acids support distinct structural profiles in proteins.
Open Biology. Roč. 12, č. 6 (2022), č. článku 220040. E-ISSN 2046-2441
Institutional support: RVO:61388963
Keywords : protein sequence space * protein structure * amino acid alphabet * genetic code evolution * random proteins
OECD category: Biochemistry and molecular biology
Impact factor: 5.8, year: 2022
Method of publishing: Open access
https://doi.org/10.1098/rsob.220040
Permanent Link: https://hdl.handle.net/11104/0332442 - 6.0556783 - ÚOCHB 2023 RIV US eng J - Journal Article
Giacobelli, V. G. - Fujishima, K. - Lepšík, Martin - Tretyachenko, V. - Kadavá, T. - Makarov, M. - Bednárová, Lucie - Novák, Petr - Hlouchová, Klára
In Vitro Evolution Reveals Noncationic Protein-RNA Interaction Mediated by Metal Ions.
Molecular Biology and Evolution. Roč. 39, č. 3 (2022), č. článku msac032. ISSN 0737-4038. E-ISSN 1537-1719
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) ED1.1.00/02.0109
EU Projects: European Commission(XE) 823839 - EPIC-XS
Research Infrastructure: e-INFRA CZ - 90140
Institutional support: RVO:61388963 ; RVO:61388971
Keywords : RNA-protein interaction * genetic code evolution * protein evolution * mRNA-display
OECD category: Biochemistry and molecular biology
Impact factor: 10.7, year: 2022
Method of publishing: Open access
https://doi.org/10.1093/molbev/msac032
Permanent Link: http://hdl.handle.net/11104/0330979File Download Size Commentary Version Access 0556783.pdf 5 982.6 KB Publisher’s postprint open-access
Research data: Mendeley Data - 7.0556704 - ÚOCHB 2023 RIV GB eng J - Journal Article
Fried, S. D. - Fujishima, K. - Makarov, M. - Cherepashuk, I. - Hlouchová, Klára
Peptides before and during the nucleotide world: An origins story emphasizing cooperation between proteins and nucleic acids.
Journal of the Royal Society Interface. Roč. 19, č. 187 (2022), č. článku 20210641. ISSN 1742-5689. E-ISSN 1742-5662
Institutional support: RVO:61388963
Keywords : origins of life * protein evolution * prebiotic polymers * early peptides
OECD category: Biochemistry and molecular biology
Impact factor: 3.9, year: 2022
Method of publishing: Open access
https://doi.org/10.1098/rsif.2021.0641
Permanent Link: http://hdl.handle.net/11104/0330849 - 8.0542938 - ÚOCHB 2022 RIV GB eng J - Journal Article
Tretyachenko, V. - Voráček, V. - Souček, Radko - Fujishima, K. - Hlouchová, Klára
CoLiDe: Combinatorial Library Design tool for probing protein sequence space.
Bioinformatics. Roč. 37, č. 4 (2021), s. 482-489. ISSN 1367-4803. E-ISSN 1460-2059
Institutional support: RVO:61388963
Keywords : algorithms * amino acid sequence * gene library
OECD category: Biochemistry and molecular biology
Impact factor: 6.931, year: 2021
Method of publishing: Open access
https://doi.org/10.1093/bioinformatics/btaa804
Permanent Link: http://hdl.handle.net/11104/0320262 - 9.0541647 - ÚOCHB 2022 RIV US eng J - Journal Article
Makarov, M. - Meng, J. - Tretyachenko, V. - Srb, Pavel - Březinová, A. - Giacobelli, V. G. - Bednárová, Lucie - Vondrášek, Jiří - Dunker, A. K. - Hlouchová, Klára
Enzyme catalysis prior to aromatic residues: Reverse engineering of a dephospho‐CoA kinase.
Protein Science. Roč. 30, č. 5 (2021), s. 1022-1034. ISSN 0961-8368. E-ISSN 1469-896X
Research Infrastructure: CIISB II - 90127
Institutional support: RVO:61388963
Keywords : aromatic amino acids * catalysis evolution * genetic code evolution * protein disorder * protein structure evolution
OECD category: Biochemistry and molecular biology
Impact factor: 6.993, year: 2021
Method of publishing: Limited access
https://doi.org/10.1002/pro.4068
Permanent Link: http://hdl.handle.net/11104/0319182 - 10.0540521 - ÚOCHB 2022 RIV GB eng J - Journal Article
Bornberg-Bauer, E. - Hlouchová, Klára - Lange, A.
Structure and function of naturally evolved de novo proteins.
Current Opinion in Structural Biology. Roč. 68, Jun (2021), s. 175-183. ISSN 0959-440X. E-ISSN 1879-033X
Institutional support: RVO:61388963
Keywords : antifreeze glycoproteins * sequence space * evolution
OECD category: Biochemistry and molecular biology
Impact factor: 7.786, year: 2021
Method of publishing: Limited access
https://doi.org/10.1016/j.sbi.2020.11.010
Permanent Link: http://hdl.handle.net/11104/0318151