Search results
- 1.0572870 - BTÚ 2024 RIV NL eng J - Journal Article
Bielcikova, Z. - Štursa, Jan - Křížová, L. - Dong, L. - Špaček, J. - Hlousek, S. - Vocka, M. - Rohlenová, Kateřina - Bartosova, O. - Černý, V. - Padrta, T. - Pesta, M. - Michálek, P. - Hubáčková, Soňa - Kološtová, K. - Pospíšilová, E. - Bobek, V. - Klezl, P. - Zobalová, Renata - Endaya, Berwini - Rohlena, Jakub - Petruzelka, L. - Werner, Lukáš - Neužil, Jiří
Mitochondrially targeted tamoxifen in patients with metastatic solid tumours: an open-label, phase I/Ib single-centre trial.
ECLINICALMEDICINE. Roč. 57, MAR 2023 (2023), č. článku 101873. E-ISSN 2589-5370
Institutional support: RVO:86652036
Keywords : Phase I * Ib clinical trial * Cancer * Mitochondrially targeted tamoxifen * Renal cell carcinoma
OECD category: General and internal medicine
Impact factor: 15.1, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S2589537023000500?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0343476 - 2.0571547 - BTÚ 2024 RIV US eng J - Journal Article
Dong, L. - Rohlena, Jakub - Zobalová, Renata - Nahácka, Zuzana - Rodriguez, A. - Berridge, M. V. V. - Neužil, Jiří
Mitochondria on the move: Horizontal mitochondrial transfer in disease and health.
Journal of Cell Biology. Roč. 222, č. 3 (2023), č. článku e202211044. ISSN 0021-9525. E-ISSN 1540-8140
R&D Projects: GA ČR(CZ) GA20-05942S; GA ČR(CZ) GX21-04607X; GA ČR(CZ) GA22-34507S; GA ČR(CZ) GA22-34507S; GA MZd(CZ) NU22-08-00160
Institutional support: RVO:86652036
Keywords : MESENCHYMAL STEM-CELLS * MULTIPOTENT STROMAL CELLS * TUNNELING NANOTUBES
OECD category: Cell biology
Impact factor: 7.8, year: 2022
Method of publishing: Open access
https://rupress.org/jcb/article/222/3/e202211044/213873/Mitochondria-on-the-move-Horizontal-mitochondrial
Permanent Link: https://hdl.handle.net/11104/0343553 - 3.0556526 - BTÚ 2023 RIV GB eng J - Journal Article
Štemberková-Hubáčková, Soňa - Zobalová, Renata - Dubišová, Maria - Šmigová, J. - Dvořáková, Šárka - Kořínková, Klára - Ezrová, Zuzana - Endaya, Berwini - Blažková, Kristýna - Vlčák, Erik - Brisudová, Petra - Le, Dan-Diem Thi - Juhás, Štefan - Rosel, D. - Kelemen, Daniela Cristina - Sovilj, Dana - Vačurová, Eliška - Čajka, Tomáš - Filimonenko, Vlada - Dong, L. - Anděra, Ladislav - Hozák, Pavel - Brabek, J. - Bielcikova, Z. - Štursa, Jan - Werner, Lukáš - Neužil, Jiří
Simultaneous targeting of mitochondrial metabolism and immune checkpoints as a new strategy for renal cancer therapy.
Clinical and Translational Medicine. Roč. 12, č. 3 (2022), č. článku e645. ISSN 2001-1326. E-ISSN 2001-1326
R&D Projects: GA ČR(CZ) GA20-05942S; GA ČR(CZ) GX21-04607X; GA ČR(CZ) GA18-02550S; GA ČR(CZ) GA19-08772S; GA MZd NU21-03-00195; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT LTC19048; GA MŠMT(CZ) LO1609; GA MŠMT(CZ) EF16_013/0001775
Grant - others:AV ČR(CZ) StrategieAV21/18
Program: StrategieAV
Institutional support: RVO:86652036 ; RVO:68378050 ; RVO:67985904 ; RVO:67985823
Keywords : Mitochondrially targeted tamoxifen * Renal cancer * Immunotherapy
OECD category: Pathology
Impact factor: 10.6, year: 2022
Method of publishing: Open access
https://onlinelibrary.wiley.com/doi/10.1002/ctm2.645
Permanent Link: http://hdl.handle.net/11104/0331774 - 4.0535784 - BTÚ 2021 RIV CH eng J - Journal Article
Dong, L. - Gopalan, V. - Holland, O. - Neužil, Jiří
Mitocans Revisited: Mitochondrial Targeting as Efficient Anti-Cancer Therapy.
International Journal of Molecular Sciences. Roč. 21, č. 21 (2020), č. článku 7941. E-ISSN 1422-0067
Institutional support: RVO:86652036
Keywords : alpha-tocopheryl succinate * overcoming drug-resistance * cervical-cancer cells * glutamine-metabolism * mitochondrial targeting
OECD category: Biochemistry and molecular biology
Impact factor: 5.924, year: 2020
Method of publishing: Open access
https://www.mdpi.com/1422-0067/21/21/7941
Permanent Link: http://hdl.handle.net/11104/0313739 - 5.0520704 - BTÚ 2020 RIV US eng J - Journal Article
Hubáčková, Soňa - Davidová, Eliška - Rohlenová, Kateřina - Štursa, Jan - Werner, Lukáš - Anděra, Ladislav - Dong, L. - Terp, M. G. - Hodný, Zdeněk - Ditzel, H. J. - Rohlena, Jakub - Neužil, Jiří
Selective elimination of senescent cells by mitochondrial targeting is regulated by ANT2.
Cell Death and Differentiation. Roč. 26, č. 2 (2019), s. 276-290. ISSN 1350-9047. E-ISSN 1476-5403
R&D Projects: GA ČR(CZ) GA18-02550S; GA ČR(CZ) GA17-07635S; GA ČR GA15-02203S; GA ČR GA16-22823S; GA ČR GA17-20904S; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT(CZ) LM2015062
Institutional support: RVO:86652036 ; RVO:68378050
Keywords : oncogene-induced senescence * cellular senescence * oxidative stress * dna-damage
OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (UMG-J)
Impact factor: 10.717, year: 2019
Method of publishing: Open access
https://www.nature.com/articles/s41418-018-0118-3
Permanent Link: http://hdl.handle.net/11104/0305395 - 6.0504151 - BTÚ 2020 RIV US eng J - Journal Article
Bajziková, Martina - Kovářová, Jaromíra - Coelho, Ana R. - Boukalová, Štěpána - Oh, S. - Rohlenová, Kateřina - Švec, David - Hubáčková, Soňa - Endaya, B. - Judasová, Kateřina - Bezawork-Geleta, A. - Klučková, Katarína - Chatre, L. - Zobalová, Renata - Nováková, Anna - Váňová, Kateřina - Ezrová, Zuzana - Maghzal, G. J. - Novais, Silvia Magalhaes - Olsinova, M. - Krobová, Linda - An, Y. J. - Davidová, Eliška - Nahácka, Zuzana - Sobol, Margaryta - Cunha-Oliveira, T. - Sandoval-Acuna, Cristian - Strnad, Hynek - Zhang, T. - Huynh, T. - Serafim, T. L. - Hozák, Pavel - Sardao, V. A. - Koopman, W. J. H. - Ricchetti, M. - Oliveira, P. J. - Kolář, František - Kubista, Mikael - Truksa, Jaroslav - Dvořáková-Hortová, Kateřina - Pacak, K. - Gürlich, R. - Stocker, R. - Zhou, Y. - Berridge, M.V. - Park, S. - Dong, L. - Rohlena, Jakub - Neužil, Jiří
Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells.
Cell Metabolism. Roč. 29, č. 2 (2019), s. 399-416. ISSN 1550-4131. E-ISSN 1932-7420
R&D Projects: GA ČR GA15-02203S; GA ČR GA16-12719S; GA ČR GA17-20904S; GA ČR GA16-22823S; GA ČR(CZ) GA16-12816S; GA ČR(CZ) GA18-11275S; GA ČR(CZ) GA18-02550S; GA MZd(CZ) NV16-31604A; GA MZd(CZ) NV17-30138A; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) LM2015062; GA ČR(CZ) GJ18-24753Y; GA MŠMT(CZ) EF16_013/0001775
Institutional support: RVO:86652036 ; RVO:67985823 ; RVO:68378050
Keywords : ELECTRON-TRANSPORT CHAIN * PANCREATIC-CANCER * MITOCHONDRIA
OECD category: Cell biology; Physiology (including cytology) (FGU-C); Cell biology (UMG-J)
Impact factor: 21.567, year: 2019
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S1550413118306466?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0295861 - 7.0474448 - BTÚ 2018 RIV GB eng J - Journal Article
Bezawork-Geleta, A. - Rohlena, Jakub - Dong, L. - Pacak, K. - Neužil, Jiří
Mitochondrial Complex II: At the Crossroads.
Trends in Biochemical Sciences. Roč. 42, č. 4 (2017), s. 312-325. ISSN 0968-0004. E-ISSN 1362-4326
R&D Projects: GA ČR GA15-02203S; GA ČR(CZ) GA16-12719S; GA ČR GA17-20904S; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:86652036
Keywords : GASTROINTESTINAL STROMAL TUMORS * SUCCINATE-DEHYDROGENASE ACTIVITY * ALPHA-TOCOPHERYL SUCCINATE
OECD category: Cell biology
Impact factor: 15.678, year: 2017
Permanent Link: http://hdl.handle.net/11104/0271499 - 8.0469007 - BTÚ 2017 RIV US eng J - Journal Article
Boukalová, Štěpána - Štursa, J. - Werner, L. - Ezrová, Zuzana - Černý, Jiří - Bezawork-Geleta, A. - Pecinová, Alena - Dong, L. - Drahota, Zdeněk - Neužil, Jiří
Mitochondrial Targeting of Metformin Enhances Its Activity against Pancreatic Cancer.
Molecular Cancer Therapeutics. Roč. 15, č. 12 (2016), s. 2875-2886. ISSN 1535-7163. E-ISSN 1538-8514
R&D Projects: GA ČR GA15-02203S; GA MZd(CZ) NV16-31604A; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:86652036 ; RVO:67985823
Keywords : ELECTRON-TRANSPORT CHAIN * RESPIRATORY COMPLEX-II * SUCCINATE
Subject RIV: FD - Oncology ; Hematology; EB - Genetics ; Molecular Biology (FGU-C)
Impact factor: 5.764, year: 2016
Permanent Link: http://hdl.handle.net/11104/0266913 - 9.0468544 - BTÚ 2017 RIV US eng J - Journal Article
Bezawork-Geleta, A. - Dong, L. - Rohlena, Jakub - Neužil, Jiří
The Assembly Factor SDHAF2 Is Dispensable for Flavination of the Catalytic Subunit of Mitochondrial Complex II in Breast Cancer Cells.
Journal of Biological Chemistry. Roč. 291, č. 41 (2016), s. 21414-21420. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR GA15-02203S; GA ČR(CZ) GA16-22823S; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:86652036
Keywords : cancer biology * mitochondrial respiratory chain complex * SUCCINATE-UBIQUINONE OXIDOREDUCTASE
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 4.125, year: 2016
Permanent Link: http://hdl.handle.net/11104/0266364 - 10.0459271 - BTÚ 2017 RIV GB eng J - Journal Article
Yan, B. - Dong, L. - Neužil, Jiří
Mitochondria: An intriguing target for killing tumour-initiating cells.
Mitochondrion. Roč. 26, JAN 2016 (2016), s. 86-93. ISSN 1567-7249. E-ISSN 1872-8278
R&D Projects: GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:86652036
Keywords : Tumour-initiating cells * ALPHA-TOCOPHERYL SUCCINATE * Therapeutic resistance * Mitochondria
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.704, year: 2016
Permanent Link: http://hdl.handle.net/11104/0259500