Search results
- 1.0584811 - BTÚ 2025 RIV GB eng J - Journal Article
Malarikova, D. - Jorda, R. - Kupcová, K. - Senavova, J. - Dolníková, A. - Pokorná, E. - Kazantsev, D. - Nozickova, K. - Sovilj, Dana - Bellanger, C. - Chiron, D. - Anděra, Ladislav - Kryštof, V. - Strnad, Miroslav - Helman, K. - Klánová, M. - Trněný, M. - Havranek, O. - Klener, P.
Cyclin dependent kinase 4/6 inhibitor palbociclib synergizes with BCL2 inhibitor venetoclax in experimental models of mantle cell lymphoma without iRB1/i deletion.
EXP HEMATOL ONCOL. Roč. 13, č. 1 (2024), č. článku 34. E-ISSN 2162-3619
Institutional support: RVO:86652036 ; RVO:61389030
Keywords : cdk4/6 * Cyclin-dependent kinase (CDK) inhibitors * Palbociclib * bcl2 * Venetoclax * rb1 * Mantle cell lymphoma (MCL)
OECD category: Oncology
Impact factor: 10.9, year: 2022
Method of publishing: Open access
https://ehoonline.biomedcentral.com/articles/10.1186/s40164-024-00499-2
Permanent Link: https://hdl.handle.net/11104/0353392 - 2.0579081 - ÚMG 2024 RIV US eng J - Journal Article
Jorda, R. - Havlíček, L. - Peřina, M. - Vojáčková, V. - Pospíšil, T. - Djukic, S. - Škerlová, Jana - Grúz, J. - Renešová, N. - Klener, P. - Řezáčová, P. - Strnad, M. - Kryštof, V.
3,5,7-Substituted Pyrazolo[4,3-id/i]Pyrimidine Inhibitors of Cyclin-Dependent Kinases and Cyclin K Degraders.
Journal of Medicinal Chemistry. Roč. 65, č. 13 (2022), s. 8881-8896. ISSN 0022-2623. E-ISSN 1520-4804
Institutional support: RVO:68378050
Keywords : roscovitine * expression * cell line
OECD category: Biochemistry and molecular biology
Impact factor: 7.3, year: 2022
Method of publishing: Limited access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c02184
Permanent Link: https://hdl.handle.net/11104/0347953 - 3.0579078 - ÚMG 2024 RIV US eng J - Journal Article
Průková, D. - Anděra, Ladislav - Nahácka, Zuzana - Karolová, J. - Svaton, M. - Klánová, M. - Havránek, O. - Soukup, J. - Svobodová, K. - Zemanová, Z. - Tušková, D. - Pokorná, E. - Helman, K. - Forsterova, K. - Pacheco-Blanco, M. - Vočková, P. - Berková, A. - Froňková, E. - Trněný, M. - Klener, P.
Cotargeting of BCL2 with Venetoclax and MCL1 with S63845 Is Synthetically Lethal In Vivo in Relapsed Mantle Cell Lymphoma.
Clinical Cancer Research. Roč. 25, č. 14 (2019), s. 4455-4465. ISSN 1078-0432. E-ISSN 1557-3265
Institutional support: RVO:68378050
Keywords : acute myeloid-leukemia * open-label * cancer * landscape * combination * cytarabine * resistance * apoptosis * overcome * abt-199
OECD category: Biochemistry and molecular biology
Impact factor: 10.107, year: 2019
Method of publishing: Limited access
https://aacrjournals.org/clincancerres/article/25/14/4455/81919/Cotargeting-of-BCL2-with-Venetoclax-and-MCL1-with
Permanent Link: https://hdl.handle.net/11104/0347951 - 4.0574366 - ÚOCHB 2024 RIV US eng J - Journal Article
Břehová, Petra - Řezníčková, E. - Škach, Kryštof - Jorda, R. - Dejmek, Milan - Vojáčková, V. - Šála, Michal - Kovalová, M. - Dračínský, Martin - Dolníková, A. - Strmeň, Timotej - Kinnertová, M. - Chalupský, Karel - Dvořáková, Alexandra - Gucký, T. - Mertlíková-Kaiserová, Helena - Klener, P. - Nencka, Radim - Kryštof, V.
Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2-b]pyridazine Derivatives Identified by Scaffold Hopping.
Journal of Medicinal Chemistry. Roč. 66, č. 16 (2023), s. 11133-11157. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MZd(CZ) NU20-05-00472; GA MŠMT LX22NPO5102
Institutional support: RVO:61388963
Keywords : gene expression * highly potent
OECD category: Oncology
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acs.jmedchem.3c00575
Permanent Link: https://hdl.handle.net/11104/0344703File Download Size Commentary Version Access 10.1021acs.jmedchem.3c00575.pdf 0 7.8 MB Publisher’s postprint open-access - 5.0562052 - ÚEB 2023 RIV US eng J - Journal Article
Jorda, R. - Havlíček, Libor - Peřina, M. - Vojáčková, V. - Pospíšil, T. - Djukic, Stefan - Škerlová, Jana - Grúz, J. - Renešová, N. - Klener, P. - Řezáčová, Pavlína - Strnad, Miroslav - Kryštof, V.
3,5,7-Substituted Pyrazolo[4,3- d]Pyrimidine Inhibitors of Cyclin-Dependent Kinases and Cyclin K Degraders.
Journal of Medicinal Chemistry. Roč. 65, č. 13 (2022), s. 8881-8896. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA ČR(CZ) GA20-25308S
Institutional support: RVO:61389030 ; RVO:61388963
Keywords : Antineoplastic Agents * Cell Line * Cyclin-Dependent Kinases
OECD category: Organic chemistry
Impact factor: 7.3, year: 2022
Method of publishing: Limited access
https://doi.org/10.1021/acs.jmedchem.1c02184
Permanent Link: https://hdl.handle.net/11104/0334472File Download Size Commentary Version Access 2022_Jorda_JOURNAL OF MEDICINAL CHEMISTRY_8881.pdf 3 9 MB Other require - 6.0557905 - ÚMG 2023 RIV US eng J - Journal Article
Klánová, M. - Kazantsev, D. - Pokorná, E. - Zikmund, T. - Karolová, J. - Behounek, M. - Renesova, N. - Sovilj, D. - Kelemen, C. - Helman, K. - Jaksa, R. - Havránek, O. - Anděra, Ladislav - Trněný, M. - Klener, P.
Anti-apoptotic MCL1 Protein Represents Critical Survival Molecule for Most Burkitt Lymphomas and BCL2-negative Diffuse Large B-cell Lymphomas.
Molecular Cancer Therapeutics. Roč. 21, č. 1 (2022), s. 89-99. ISSN 1535-7163. E-ISSN 1538-8514
Institutional support: RVO:68378050
Keywords : gene-expression * elderly-patients * bcl-2 family * venetoclax * chemotherapy * inhibition * mutations * subgroups * abt-199 * dlbcl
OECD category: Oncology
Impact factor: 5.7, year: 2022
Method of publishing: Open access
https://aacrjournals.org/mct/article/21/1/89/675161/Anti-apoptotic-MCL1-Protein-Represents-Critical
Permanent Link: http://hdl.handle.net/11104/0331789 - 7.0554915 - ÚMG 2022 RIV CH eng J - Journal Article
Klener, P. - Sovilj, D. - Renesova, N. - Anděra, Ladislav
BH3 Mimetics in Hematologic Malignancies.
International Journal of Molecular Sciences. Roč. 22, č. 18 (2021), č. článku 10157. E-ISSN 1422-0067
Institutional support: RVO:68378050
Keywords : apoptosis * BH3 mimetics * venetoclax * hematologic malignancies * targeted therapy * resistance * biomarkers
OECD category: Biochemistry and molecular biology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1422-0067/22/18/10157
Permanent Link: http://hdl.handle.net/11104/0329534 - 8.0554659 - BTÚ 2023 RIV US eng J - Journal Article
Klánová, M. - Kazantsev, D. - Pokorná, E. - Zikmund, T. - Karolová, J. - Behounek, M. - Renesova, N. - Sovilj, Dana - Kelemen, Cristina D. - Helman, K. - Jaksa, R. - Havranek, O. - Anděra, Ladislav - Trněný, M. - Klener, P.
Anti-apoptotic MCL1 Protein Represents Critical Survival Molecule for Most Burkitt Lymphomas and BCL2-negative Diffuse Large B-cell Lymphomas.
Molecular Cancer Therapeutics. Roč. 21, č. 1 (2022), s. 89-99. ISSN 1535-7163. E-ISSN 1538-8514
R&D Projects: GA ČR(CZ) GA19-08772S; GA MZd(CZ) NU21-03-00386
Institutional support: RVO:86652036
Keywords : gene-expression * elderly-patients * bcl-2 family * venetoclax * chemotherapy
OECD category: Oncology
Impact factor: 5.7, year: 2022
Method of publishing: Open access
https://aacrjournals.org/mct/article/21/1/89/675161/Anti-apoptotic-MCL1-Protein-Represents-Critical
Permanent Link: http://hdl.handle.net/11104/0331895 - 9.0552542 - ÚMCH 2023 RIV CH eng J - Journal Article
Etrych, Tomáš - Braunová, Alena - Zogala, D. - Lambert, L. - Renesova, N. - Klener, P.
Targeted drug delivery and theranostic strategies in malignant lymphomas.
Cancers (Basel). Roč. 14, č. 3 (2022), č. článku 626. E-ISSN 2072-6694
R&D Projects: GA ČR(CZ) GA19-01417S
Institutional support: RVO:61389013
Keywords : targeted drug delivery * theranostics * lymphoma
OECD category: Polymer science
Impact factor: 5.2, year: 2022
Method of publishing: Open access
https://www.mdpi.com/2072-6694/14/3/626
Permanent Link: http://hdl.handle.net/11104/0327964 - 10.0550596 - BTÚ 2022 RIV CH eng J - Journal Article
Klener, P. - Sovilj, Dana - Renesova, N. - Anděra, Ladislav
BH3 Mimetics in Hematologic Malignancies.
International Journal of Molecular Sciences. Roč. 22, č. 18 (2021), č. článku 10157. E-ISSN 1422-0067
R&D Projects: GA MZd(CZ) NU21-03-00386; GA ČR(CZ) GA19-08772S
Institutional support: RVO:86652036
Keywords : apoptosis * venetoclax * BH3 mimetics * hematologic malignancies
OECD category: Biochemistry and molecular biology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1422-0067/22/18/10157
Permanent Link: http://hdl.handle.net/11104/0326720