Search results
- 1.0580663 - ÚOCHB 2024 RIV jpn P - Patent Document
Slusher, B. - Rais, R. - Majer, Pavel - Tenora, Lukáš - Novotná, Kateřina - Alt, J.
新規なグルタミンアンタゴニストおよびそれらの使用.
[Novel glutamine antagonists and uses thereof.]
2023. Owner: The Johns Hopkins University - Ústav organické chemie a biochemie AV ČR, v. v. i. Date of the patent acceptance: 10.10.2023. Patent Number: JP7358342. Territorial Protection: národní patent v zemi mimo EU ,mezinárodní patentová ochrana dle Smlouvy o patentové spolupráci.
R&D Projects: GA MŠMT LTAUSA18166
Institutional support: RVO:61388963
Keywords : glutamine antagonists * 6-diazo-5-oxo-L-norleucine * prodrug strategies
OECD category: Organic chemistry
https://worldwide.espacenet.com/patent/search/family/065994832/publication/JP7358342B2?q=JP7358342B2
Permanent Link: https://hdl.handle.net/11104/0349426 - 2.0580592 - ÚOCHB 2024 RIV eng P - Patent Document
Slusher, B. - Rais, R. - Majer, Pavel - Tenora, Lukáš - Novotná, Kateřina - Alt, J.
Novel glutamine antagonists and uses thereof.
2022. Owner: The Johns Hopkins University - Ústav organické chemie a biochemie AV ČR, v. v. i. Date of the patent acceptance: 24.08.2022. Patent Number: EP3692015. Territorial Protection: evropský patent podle Evropské patentové úmluvy ,mezinárodní patentová ochrana dle Smlouvy o patentové spolupráci.
R&D Projects: GA MŠMT LTAUSA18166
Institutional support: RVO:61388963
Keywords : glutamine antagonists * 6-diazo-5-oxo-L-norleucine * prodrug strategies
OECD category: Organic chemistry
https://worldwide.espacenet.com/patent/search/family/065994832/publication/EP3692015B1?q=EP3692015B1
Permanent Link: https://hdl.handle.net/11104/0349359 - 3.0580041 - ÚOCHB 2024 RIV eng P - Patent Document
Slusher, B. - Rais, R. - Riggins, G. - Majer, Pavel - Tichý, Tomáš - Vávra, Jan - Jančařík, Andrej - Tenora, Lukáš
Mebendazole prodrugs with enhanced solubility and oral bioavailability.
2023. Owner: The Johns Hopkins University - Ústav organické chemie a biochemie AV ČR, v. v. i. Date of the patent acceptance: 14.09.2023. Patent Number: AU2019216757. Territorial Protection: národní patent v zemi mimo EU ,mezinárodní patentová ochrana dle Smlouvy o patentové spolupráci.
Institutional support: RVO:61388963
Keywords : mebendazole * prodrug * oral bioavailability
OECD category: Medicinal chemistry
https://worldwide.espacenet.com/patent/search/family/067549070/publication/AU2019216757B2?q=AU2019216757B2
Permanent Link: https://hdl.handle.net/11104/0348822 - 4.0577575 - ÚOCHB 2024 RIV eng P - Patent Document
Slusher, B. - Rais, R. - Riggins, G. - Majer, Pavel - Tichý, Tomáš - Vávra, Jan - Jančařík, Andrej - Tenora, Lukáš
Mebendazole prodrugs with enhanced solubility and oral bioavailability.
2023. Owner: The Johns Hopkins University - Ústav organické chemie a biochemie AV ČR, v. v. i. Date of the patent acceptance: 01.08.2023. Patent Number: US11712435. Territorial Protection: národní patent v zemi mimo EU ,mezinárodní patentová ochrana dle Smlouvy o patentové spolupráci.
Institutional support: RVO:61388963
Keywords : mebendazole * prodrug * oral bioavailability
OECD category: Medicinal chemistry
https://worldwide.espacenet.com/patent/search/family/067549070/publication/US11712435B2?q=US11712435B2
Permanent Link: https://hdl.handle.net/11104/0346694 - 5.0566963 - ÚOCHB 2023 RIV eng P - Patent Document
Slusher, B. - Rojas, C. - Thomas, A. G. - Nencka, Radim - Šála, Michal - Hřebabecký, Hubert - Haughey, N.
Small molecule inhibitors of neutral sphingomyelinase 2 (nSMase2) for the treatment of neurodegenerative diseases.
2022. Owner: The Johns Hopkins University - Ústav organické chemie a biochemie AV ČR v. v. i. Date of the patent acceptance: 30.08.2022. Patent Number: US11427590
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : nSMase2 * Alzheimer’s disease * brain penetration
OECD category: Medicinal chemistry
https://worldwide.espacenet.com/patent/search/family/062791143/publication/US11427590B2?q=pn%3DUS11427590B2
Permanent Link: https://hdl.handle.net/11104/0338223 - 6.0559907 - ÚOCHB 2023 RIV eng P - Patent Document
Slusher, B. - Rojas, C. - Thomas, A. G. - Nencka, Radim - Šála, Michal - Hřebabecký, Hubert
Small molecule inhibitors of neutral sphingomyelinase 2 (nSMase2) for the treatment of neurodegenerative diseases.
2022. Owner: The Johns Hopkins University - Ústav organické chemie a biochemie AV ČR v. v. i. Date of the patent acceptance: 14.04.2022. Patent Number: AU2018205277
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : nSMase2 * Alzheimer’s disease * brain penetration
OECD category: Medicinal chemistry
https://worldwide.espacenet.com/patent/search/family/062791143/publication/AU2018205277B2?q=AU2018205277B2
Permanent Link: https://hdl.handle.net/11104/0333032 - 7.0559889 - ÚOCHB 2023 RIV eng P - Patent Document
Slusher, B. - Rais, R. - Krečmerová, Marcela - Tichý, Tomáš - Majer, Pavel - Jančařík, Andrej
Prodrugs of prostate specific membrane antigen (PSMA) inhibitor.
2022. Owner: The Johns Hopkins University - Ústav organické chemie a biochemie AV ČR, v. v. i. Date of the patent acceptance: 10.05.2022. Patent Number: US11325931
Institutional support: RVO:61388963
Keywords : 2-Phosphonomethylpentanedioic acid (2-PMPA) * glutamate carboxypeptidase II * GCPII * PSMA * pivaloyloxymethyl * isopropyloxycarbonyloxymethyl * POM * POC * prodrug
OECD category: Organic chemistry
https://worldwide.espacenet.com/patent/search/family/055264571/publication/US11325931B2?q=US11325931B2
Permanent Link: https://hdl.handle.net/11104/0333018 - 8.0559886 - ÚOCHB 2023 RIV eng P - Patent Document
Slusher, B. - Rais, R. - Krečmerová, Marcela - Tichý, Tomáš - Majer, Pavel - Jančařík, Andrej
Prodrugs of prostate specific membrane antigen (PSMA) inhibitor.
2022. Owner: The Johns Hopkins University - Ústav organické chemie a biochemie AV ČR, v. v. i. Date of the patent acceptance: 12.01.2022. Patent Number: EP3177632
Institutional support: RVO:61388963
Keywords : 2-Phosphonomethylpentanedioic acid (2-PMPA) * glutamate carboxypeptidase II * GCPII * PSMA * pivaloyloxymethyl * isopropyloxycarbonyloxymethyl * POM * POC * prodrug
OECD category: Organic chemistry
https://worldwide.espacenet.com/patent/search/family/055264571/publication/EP3177632B1?q=EP3177632B1
Permanent Link: https://hdl.handle.net/11104/0333015 - 9.0541959 - ÚOCHB 2022 RIV jpn P - Patent Document
Slusher, B. - Rais, R. - Tenora, Lukáš - Majer, Pavel - Jančařík, Andrej
グルタミン類似体のプロドラッグ.
[Prodrugs of glutamine analogs.]
2021. Owner: The Johns Hopkins University. - Ústav organické chemie a biochemie AV ČR, v. v. i. Date of the patent acceptance: 21.04.2021. Patent Number: JP6863981
Institutional support: RVO:61388963
Keywords : 6-diazo-5-oxo-L-norleucine (DON) * prodrugs * cancer
OECD category: Organic chemistry
https://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20210421&DB=&locale=en_EP&CC=JP&NR=6863981B2&KC=B2&ND=5
Permanent Link: http://hdl.handle.net/11104/0319470 - 10.0541954 - ÚOCHB 2022 RIV eng P - Patent Document
Slusher, B. - Rais, R. - Tenora, Lukáš - Majer, Pavel - Jančařík, Andrej
Prodrugs of glutamine analogs.
2021. Owner: The Johns Hopkins University. - Ústav organické chemie a biochemie AV ČR, v. v. i. Date of the patent acceptance: 23.03.2021. Patent Number: US10954257
Institutional support: RVO:61388963
Keywords : 6-diazo-5-oxo-L-norleucine (DON) * prodrugs * cancer
OECD category: Organic chemistry
https://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20210323&DB=&locale=en_EP&CC=US&NR=10954257B2&KC=B2&ND=5
Permanent Link: http://hdl.handle.net/11104/0319466