Search results
- 1.0335281 - BC 2010 RIV US eng J - Journal Article
Ovat, A. - Muindi, F. - Fagan, C. - Brouner, M. - Hansell, E. - Dvořák, J. - Sojka, Daniel - Kopáček, Petr - McKerrow, J. H. - Caffrey, C. R. - Powers, J. C.
Aza-Peptidyl Michael Acceptor and Epoxide Inhibitors—Potent and Selective Inhibitors of Schistosoma mansoni and Ixodes ricinus Legumains (Asparaginyl Endopeptidases).
Journal of Medicinal Chemistry. Roč. 52, č. 22 (2009), s. 7192-7210. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR GA206/06/0865; GA MŠMT(CZ) LC06009
Institutional research plan: CEZ:AV0Z60220518
Keywords : legumain * IrAE * aza-peptide Michael acceptors
Subject RIV: EC - Immunology
Impact factor: 4.802, year: 2009
Permanent Link: http://hdl.handle.net/11104/0179788 - 2.0333131 - ÚOCHB 2010 RIV US eng J - Journal Article
Horn, Martin - Nussbaumerová, Martina - Šanda, Miloslav - Kovářová, Zuzana - Srba, Jindřich - Franta, Zdeněk - Sojka, Daniel - Bogyo, M. - Caffrey, C. R. - Kopáček, Petr - Mareš, Michael
Hemoglobin digestion in blood-feeding ticks: mapping of multipeptidase pathway by functional proteomics.
Chemistry & Biology. Roč. 16, č. 10 (2009), s. 1053-1063. ISSN 1074-5521
R&D Projects: GA ČR GA206/06/0865; GA AV ČR IAA600960910; GA MŠMT(CZ) LC06009; GA AV ČR KJB400550516
Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z60220518
Keywords : peptidases * active-site probes * hemoglobinolysis * tick digestion * Ixodes ricinus
Subject RIV: CE - Biochemistry
Impact factor: 6.523, year: 2009
Permanent Link: http://hdl.handle.net/11104/0178196 - 3.0318080 - BC 2009 RIV US eng J - Journal Article
Götz, M. G. - James, K. E. - Hansell, E. - Dvořák, J. - Seshaadri, A. - Sojka, Daniel - Kopáček, Petr - McKerrow, J. H. - Caffrey, C. R. - Powers, J. C.
Aza-peptidyl Michael acceptors. A new class of potent and selective inhibitors of asparaginyl endopeptidases (legumains) from evolutionarily diverse pathogens.
[Aza-peptidy Michael Acceptors. Nová třída účinných a selektivních inhibitorů asparaginylových peptidáz (legumainů) z evolučně vzdálených patogenů.]
Journal of Medicinal Chemistry. Roč. 51, č. 9 (2008), s. 2816-2832. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) LC06009; GA ČR GA206/06/0865
Grant - others:The National Institute of Allergy and Infectious Diseases(US) AI053247; National Institute of General Medical Sciences(US) GM54404; National Institute of General Medical Sciences(US) GM61964
Institutional research plan: CEZ:AV0Z60220518
Keywords : legumain * IrAE * aza-peptide Michael acceptors
Subject RIV: ED - Physiology
Impact factor: 4.898, year: 2008
Permanent Link: http://hdl.handle.net/11104/0167567 - 4.0306907 - BC 2008 RIV GB eng J - Journal Article
Sojka, Daniel - Franta, Zdeněk - Horn, Martin - Hajdušek, O. - Caffrey, C. R. - Mareš, Michael - Kopáček, Petr
Profiling of proteolytic enzymes in the gut of the tick Ixodes ricinus reveals an evolutionarily conserved network of aspartic and cysteine peptidases.
[Profil proteolytických enzymů střeva klíštěte Ixodes ricinus odpovídá evolučně konzervovanému komplexu aspartových a cysteinových peptidáz.]
Parasites & Vectors. Roč. 1, - (2008), s. 1-14. ISSN 1756-3305. E-ISSN 1756-3305
R&D Projects: GA ČR GA206/06/0865; GA MŠMT(CZ) LC06009; GA AV ČR KJB400550516; GA ČR GD524/03/H133
Institutional research plan: CEZ:AV0Z60220518; CEZ:AV0Z40550506
Keywords : cathepsin * tick gut * blood digestion
Subject RIV: ED - Physiology
http://www.parasitesandvectors.com/content/1/1/7
Permanent Link: http://hdl.handle.net/11104/0159808 - 5.0087229 - BC 2008 RIV AU eng J - Journal Article
Sojka, Daniel - Hajdušek, Ondřej - Dvořák, J. - Sajid, M. - Franta, Zdeněk - Schneider, E. L. - Craik, C. S. - Vancová, Marie - Burešová, Veronika - Bogyo, M. - Sexton, K. B. - McKerrow, J. H. - Caffrey, C. R. - Kopáček, Petr
IrAE - An asparaginyl endopeptidase (legumain) in the gut of the hard tick Ixodes ricinus.
[IrAE – asparaginylová endopeptidáza (legumain) ve střevě klíštěte Ixodes ricinus.]
International Journal for Parasitology. Roč. 37, č. 7 (2007), s. 713-724. ISSN 0020-7519. E-ISSN 1879-0135
R&D Projects: GA ČR GA206/06/0865; GA AV ČR IAA6022307; GA MŠMT(CZ) LC06009; GA ČR GD524/03/H133
Grant - others:GA MŠk(CZ) FRVŠ 3646/2005; NIH(US) AI35707
Institutional research plan: CEZ:AV0Z60220518
Source of funding: V - Other public resources
Keywords : asparaginyl endopeptidase * tick gut, * blood digestion
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.392, year: 2007
Permanent Link: http://hdl.handle.net/11104/0149128 - 6.0047963 - ÚOCHB 2007 RIV DE eng J - Journal Article
Grunclová, L. - Horn, Martin - Vancová, Marie - Sojka, D. - Franta, Z. - Mareš, Michael - Kopáček, Petr
Two secreted cystatins of the soft tick Ornithodoros moubata: differential expression pattern and inhibitory specificity.
[Dva sekretované cystatiny z klíšťáka Ornithodoros moubata: rozdíly v expresy a inhibiční specifitě.]
Biological Chemistry. Roč. 387, č. 12 (2006), s. 1635-1644. ISSN 1431-6730. E-ISSN 1437-4315
R&D Projects: GA AV ČR(CZ) IAA6022307; GA ČR(CZ) GA206/06/0865; GA MŠMT(CZ) LC06009
Grant - others:FRVŠ(CZ) 524/03/H133
Institutional research plan: CEZ:AV0Z60220518; CEZ:AV0Z40550506
Keywords : cystatin * tick * midgut
Subject RIV: CE - Biochemistry
Impact factor: 2.752, year: 2006
Permanent Link: http://hdl.handle.net/11104/0138721