Search results

  1. 1.
    0587571 - ÚOCHB 2025 RIV US eng J - Journal Article
    Hadzima, Martin - Faucher, F. F. - Blažková, K. - Yim, J. J. - Guerra, M. - Chen, S. - Woods, E. C. - Park, K. W. - Šácha, Pavel - Šubr, Vladimír - Kostka, Libor - Etrych, Tomáš - Majer, Pavel - Konvalinka, Jan - Bogyo, M.
    Polymer-Tethered Quenched Fluorescent Probes for Enhanced Imaging of Tumor-Associated Proteases.
    ACS Sensors. (2024). ISSN 2379-3694. E-ISSN 2379-3694
    R&D Projects: GA MŠMT LX22NPO5102; GA MŠMT(CZ) EF18_053/0016940; GA MZd(CZ) NU21-08-00280; GA ČR(CZ) GA23-05642S
    Institutional support: RVO:61388963 ; RVO:61389013
    Keywords : fluorescence * imaging * protease * cancer * HPMA copolymer * iBody
    Impact factor: 8.9, year: 2022
    Method of publishing: Open access
    https://doi.org/10.1021/acssensors.4c00912
    Permanent Link: https://hdl.handle.net/11104/0354701
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    10.1021acssensors.4c00912.pdf16 MBPublisher’s postprintopen-access
     
     
  2. 2.
    0587261 - ÚMCH 2025 RIV US eng J - Journal Article
    Castillo Henríquez, L. - Bahloul, B. - Alhareth, K. - Oyoun, F. - Frejková, Markéta - Kostka, Libor - Etrych, Tomáš - Kalshoven, L. - Guillaum, A. - Mignet, N. - Corvis, Y.
    Step-by-step standardization of the bottom-up semi-automated nanocrystallization of pharmaceuticals: a quality by design and design of experiments joint approach.
    Small. Roč. 20, č. 25 (2024), č. článku 2306054. ISSN 1613-6810. E-ISSN 1613-6829
    Grant - others:AV ČR(CZ) CNRS-22-01
    Program: Bilaterální spolupráce
    Institutional support: RVO:61389013
    Keywords : design space * nanocrystals * orthogonal characterization
    OECD category: Polymer science
    Impact factor: 13.3, year: 2022
    Method of publishing: Open access
    https://onlinelibrary.wiley.com/doi/10.1002/smll.202306054
    Permanent Link: https://hdl.handle.net/11104/0354692
     
     
  3. 3.
    0586357 - ÚOCHB 2025 RIV NL eng J - Journal Article
    Zamani, Mohammad Reza - Hadzima, Martin - Blažková, Kristýna - Šubr, Vladimír - Ormsby, Tereza - Celis-Gutierrez, J. - Malissen, B. - Kostka, Libor - Etrych, Tomáš - Šácha, Pavel - Konvalinka, Jan
    Polymer-based antibody mimetics (iBodies) target human PD-L1 and function as a potent immune checkpoint blocker.
    Journal of Biological Chemistry. Roč. 300, č. 6 (2024), č. článku 107325. ISSN 0021-9258. E-ISSN 1083-351X
    R&D Projects: GA MŠMT LX22NPO5102; GA ČR(CZ) GA23-05642S
    Institutional support: RVO:61388963 ; RVO:61389013
    Keywords : antibody mimetic * HPMA copolymer * mmune checkpoint * immunosuppression * immunotherapy * inhibitor * PD-1 * PD-L1 * T-cell * tumor immunology
    Subject RIV: CD - Macromolecular Chemistry (UMCH-V)
    OECD category: Polymer science (UMCH-V)
    Impact factor: 4.8, year: 2022
    Method of publishing: Open access
    https://doi.org/10.1016/j.jbc.2024.107325
    Permanent Link: https://hdl.handle.net/11104/0353904
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    10.1016j.jbc.2024.107325.pdf11.6 MBPublisher’s postprintopen-access
     
     
  4. 4.
    0585892 - ÚMCH 2025 RIV US eng J - Journal Article
    Sansee, A. - Kostka, Libor - Marcalíková, Adéla - Kudláčová, Júlia - Sedlák, František - Kotrchová, Lenka - Šácha, Pavel - Etrych, Tomáš - Kielar, F.
    Iridium-based polymeric multifunctional imaging tools for biochemistry.
    ChemPlusChem. Roč. 89, č. 5 (2024), č. článku e202300647. ISSN 2192-6506. E-ISSN 2192-6506
    R&D Projects: GA ČR(CZ) GA23-05642S; GA MŠMT LX22NPO5102
    Institutional support: RVO:61389013 ; RVO:61388963
    Keywords : HPMA * iridium complex * imaging
    OECD category: Polymer science; Medicinal chemistry (UOCHB-X)
    Impact factor: 3.4, year: 2022
    Method of publishing: Open access
    https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cplu.202300647
    Permanent Link: https://hdl.handle.net/11104/0353702
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    0585892.pdf02.3 MBCC BY LicensePublisher’s postprintopen-access
     
     
  5. 5.
    0583958 - ÚMCH 2025 RIV CH eng J - Journal Article
    Šubr, Vladimír - Kostka, Libor - Plicka, J. - Sedláček, O. - Etrych, Tomáš
    Highly effective synthetic polymer-based blockers of non-specific interactions in immunochemical analyses.
    Polymers. Roč. 16, č. 6 (2024), č. článku 758. E-ISSN 2073-4360
    R&D Projects: GA ČR(CZ) GA23-05642S; GA TA ČR(CZ) TN02000122; GA MŠMT LX22NPO5102
    Institutional support: RVO:61389013
    Keywords : HPMA copolymer * blocker * non-specific interactions
    OECD category: Polymer science
    Impact factor: 5, year: 2022
    Method of publishing: Open access
    https://www.mdpi.com/2073-4360/16/6/758
    Permanent Link: https://hdl.handle.net/11104/0352006
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    0583958.pdf02.2 MBCreative Commons Attribution (CC BY) licensePublisher’s postprintopen-access
     
     
  6. 6.
    0583051 - ÚMCH 2025 RIV US eng J - Journal Article
    Kudláčová, Júlia - Kužílková, D. - Bárta, F. - Brdičková, N. - Vávrová, A. - Kostka, Libor - Hovorka, O. - Kalina, T. - Etrych, Tomáš
    Hybrid macromolecular constructs as a platform for spectral nanoprobes for advanced cellular barcoding in flow cytometry.
    Macromolecular Bioscience. Roč. 24, č. 2 (2024), č. článku 2300306. ISSN 1616-5187. E-ISSN 1616-5195
    R&D Projects: GA MZd(CZ) NU21-08-00280; GA MPO(CZ) FV10370; GA MŠMT LX22NPO5102
    Institutional support: RVO:61389013
    Keywords : antibody-polymer-dye conjugates * cellular barcoding * double fluorescence
    OECD category: Polymer science
    Impact factor: 4.6, year: 2022
    Method of publishing: Open access
    https://onlinelibrary.wiley.com/doi/10.1002/mabi.202300306
    Permanent Link: https://hdl.handle.net/11104/0351049
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    0583051.pdf02.1 MBCC BY 4.0 Deed Attribution 4.0 InternationalPublisher’s postprintopen-access
     
     
  7. 7.
    0580702 - MBÚ 2025 RIV NL eng J - Journal Article
    Kovář, Marek - Šubr, Vladimír - Běhalová, Kateřina - Studenovský, Martin - Starenko, Daniil - Kovářová, Jiřina - Procházková, Petra - Etrych, Tomáš - Kostka, Libor
    Chemosensitization of tumors via simultaneous delivery of STAT3 inhibitor and doxorubicin through HPMA copolymer-based nanotherapeutics with pH-sensitive activation.
    Nanomedicine: Nanotechnology, Biology and Medicine. Roč. 56, February 2024 (2024), s. 102730. ISSN 1549-9634. E-ISSN 1549-9642
    R&D Projects: GA MZd(CZ) NU21-03-00273; GA MŠMT LX22NPO5102
    Institutional support: RVO:61388971 ; RVO:61389013
    Keywords : STAT3 inhibitor * Doxorubicin * HPMA copolymer carrier * pH-sensitive drug * release
    OECD category: Pharmacology and pharmacy; Medicinal chemistry (UMCH-V)
    Impact factor: 5.4, year: 2022
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S1549963423000813
    Permanent Link: https://hdl.handle.net/11104/0349459
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    0580702.pdf15 MBCC BY licensePublisher’s postprintopen-access
    Kovar et al_Nanomedicine.pdf05 MBPublisher’s postprintopen-access
     
     
  8. 8.
    0578323 - ÚMCH 2024 RIV NL eng J - Journal Article
    Pechar, Michal - Král, Vlastimil - Kracíková, Lucie - Androvič, Ladislav - Hrdá, Eliška - Pola, Robert - Pytlíková, Sára - Studenovský, Martin - Kostka, Libor - Šubr, Vladimír - Etrych, Tomáš - Kočková, Olga - Ferreira Mendes, Jessica Marianne - Fábry, Milan - Laga, Richard
    Tumor-specific targeting of polymer drug delivery systems with recombinant proteins bound via tris(nitrilotriacetic acid).
    International Journal of Pharmaceutics. Roč. 648, 15 December (2023), č. článku 123619. ISSN 0378-5173. E-ISSN 1873-3476
    R&D Projects: GA MŠMT LX22NPO5102
    Institutional support: RVO:61389013 ; RVO:61388963
    Keywords : hydrophilic polymers * thermo-responsive polymers * polymer drug delivery system
    OECD category: Polymer science; Biochemistry and molecular biology (UOCHB-X)
    Impact factor: 5.8, year: 2022
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S0378517323010414?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0347753
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    0578323.pdf04.4 MBLicense CC BY 4.0Publisher’s postprintopen-access
     
     
  9. 9.
    0576932 - ÚMCH 2024 RIV NL eng J - Journal Article
    Hrochová, Michaela - Kotrchová, Lenka - Frejková, Markéta - Konefal, Rafal - Gao, S. - Fang, J. - Kostka, Libor - Etrych, Tomáš
    Adaptable polymerization platform for therapeutics with tunable biodegradability.
    Acta Biomaterialia. Roč. 171, November (2023), s. 417-427. ISSN 1742-7061. E-ISSN 1878-7568
    R&D Projects: GA MZd(CZ) NU21-03-00273; GA MŠMT LX22NPO5102
    Grant - others:AV ČR(CZ) MSM200502104; AV ČR(CZ) JSPS-22-01
    Program: Program na podporu mezinárodní spolupráce začínajících výzkumných pracovníků; Bilaterální spolupráce
    Institutional support: RVO:61389013
    Keywords : HPMA * RAFT polymerization * drug delivery
    OECD category: Polymer science
    Impact factor: 9.7, year: 2022
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S174270612300538X?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0346312
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    0576932.pdf12.3 MBCC BY LicensePublisher’s postprintopen-access
     
     
  10. 10.
    0565337 - ÚMCH 2024 RIV NL eng J - Journal Article
    Kostka, Libor - Kotrchová, Lenka - Randárová, Eva - Ferreira, C. A. - Malátová, Iva - Lee, H. J. - Olson, A. P. - Engle, J. W. - Kovář, Marek - Cai, W. - Šírová, Milada - Etrych, Tomáš
    Evaluation of linear versus star-like polymer anti-cancer nanomedicines in mouse models.
    Journal of Controlled Release. Roč. 353, January (2023), s. 549-562. ISSN 0168-3659. E-ISSN 1873-4995
    R&D Projects: GA MŠMT LX22NPO5102; GA MŠMT(CZ) LTAUSA18083
    Grant - others:AV ČR(CZ) MSM200502104
    Program: Program na podporu mezinárodní spolupráce začínajících výzkumných pracovníků
    Institutional support: RVO:61389013 ; RVO:61388971
    Keywords : drug delivery * cancer * polymeric carriers
    OECD category: Polymer science; Pharmacology and pharmacy (MBU-M)
    Impact factor: 10.8, year: 2022
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S0168365922008148?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0336896
    FileDownloadSizeCommentaryVersionAccess
    0565337.pdf08 MBCreative Commons Attribution 4.0 International License (CC BY)Publisher’s postprintopen-access
     
     

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